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51.

518
Accesses

Research   Open Access Highly Accessed

Patterns of anti-malarial drug treatment among pregnant women in Uganda

Laura R Sangaré, Noel S Weiss, Paula E Brentlinger, Barbra A Richardson, Sarah G Staedke, Mpungu S Kiwuwa, Andy Stergachis Malaria Journal 2011, 10:152 (6 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Overuse of anti-malarial drugs, especially ones that are no longer recommended, undermines malaria control efforts by fueling the spread of drug resistance and delaying appropriate treatment of non-malarial febrile illnesses. Improved diagnostic capacity is essential to ultimately improving the management of malaria-like symptoms during pregnancy and appropriate use of currently available anti-malarials.

52.

513
Accesses

Review   Open Access Highly Accessed

Determinants of relapse periodicity in Plasmodium vivax malaria

Nicholas J White Malaria Journal 2011, 10:297 (11 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A review describing current and, more importantly, past (and forgotten) understanding of the biology of relapse in P. vivax malaria. It provides a welcome treasure trove of citations to that older literature, in addition to putting forth an interesting new hypothesis worthy of testing, i.e., activation of hypnozoites by febrile illness.

53.

510
Accesses

Research   Open Access

A member of the Plasmodium falciparum PHIST family binds to the erythrocyte cytoskeleton component band 4.1

Lindsay A Parish, Deborah W Mai, Matthew L Jones, Erika L Kitson, Julian C Rayner Malaria Journal 2013, 12:160 (11 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Identification of a novel interaction between the erythrocyte Band 4.1 protein and a P. falciparum component from the PHIST family of proteins. The paper should be of interest to groups working on the parasite "exportome".

54.

504
Accesses

Research   Open Access

Providing open access data online to advance malaria research and control

Catherine L Moyes, William H Temperley, Andrew J Henry, Clara R Burgert, Simon I Hay Malaria Journal 2013, 12:161 (16 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

A description of the construction of the Malaria Atlas Project's online data portal. It usefully details the data and associated products that the MAP team has made accessible to the global malaria community.

55.

494
Accesses

Review   Open Access Highly Accessed

Mathematical models of malaria - a review

Sandip Mandal, Ram Sarkar, Somdatta Sinha Malaria Journal 2011, 10:202 (21 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A timely review article that aims to assess the current state of the malaria modelling field, predominantly focusing on mathematical (rather than statistical) models.

56.

485
Accesses

Research   Open Access Highly Accessed

Treatment of fevers prior to introducing rapid diagnostic tests for malaria in registered drug shops in Uganda

Anthony K Mbonye, Sham Lal, Bonnie Cundill, Kristian Schultz Hansen, Siân Clarke, Pascal Magnussen Malaria Journal 2013, 12:131 (16 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

In this setting, the proportion of malaria patients receiving appropriate ACT treatment at drug shops was low. This was due to the practice of presumptive treatment, inadequate training on malaria management and lack of knowledge that ACT was the recommended first-line treatment for malaria.

57.

476
Accesses

Research   Open Access Highly Accessed

Gender differences in the use of insecticide-treated nets after a universal free distribution campaign in Kano State, Nigeria: post-campaign survey results

Ashley E Garley, Elizabeth Ivanovich, Erin Eckert, Svetlana Negroustoueva, Yazoume Ye Malaria Journal 2013, 12:119 (10 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

It is clear that ITN strategies not only need to address the difference in uptake between ¿sex¿ but also among other gender inequalities, such as adolescent boys, who seem to have a lower use of ITNs than any other group.

58.

472
Accesses

Reviewer acknowledgement   Open Access Highly Accessed

Reviewer acknowledgement

Marcel Hommel Malaria Journal 2013, 12:83 (17 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

59.

476
Accesses

Research   Open Access Highly Accessed

Morphological features and differential counts of Plasmodium knowlesi parasites in naturally acquired human infections

Kim-Sung Lee, Janet Cox-Singh, Balbir Singh Malaria Journal 2009, 8:73 (21 April 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The morphological resemblance of early trophozoites of P. knowlesi to P. falciparum and later erythrocytic stages to P. malariae makes it extremely difficult to identify P. knowlesi infections by microscopy alone. This is the first, extensive description of the various stages of the parasite as seen in stained blood films.

60.

470
Accesses

Research   Open Access Highly Accessed

A mathematical model of the impact of present and future malaria vaccines

Edward A Wenger, Philip A Eckhoff Malaria Journal 2013, 12:126 (15 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A mathematical modelling exercise to evaluate the impact of a vaccine with properties like RTS,S across a range of transmission settings and in the presence of other interventions. The model makes sensible assumptions, and it is explained in terms that are reasonably easy for a non-expert to grasp.

61.

468
Accesses

Review   Open Access Highly Accessed

Human malarial disease: a consequence of inflammatory cytokine release

Ian A Clark, Alison C Budd, Lisa M Alleva, William B Cowden Malaria Journal 2006, 5:85 (10 October 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Malariologists tend to think that the pathophysiology of malaria is unique. This thought-provoking review shows that much can be learned from events described with other pathogens and that falciparum malaria is primarily an inflammatory cytokine-driven disease. In particular, the inability of mitochondria, through the effects of inflammatory cytokines, to utilise available oxygen may play a crucial role.

62.

465
Accesses

Research   Open Access

'A mate or a meal' – Pre-gravid behaviour of female Anopheles gambiae from the islands of São Tomé and Príncipe, West Africa

J Derek Charlwood, Joao Pinto, Carla A Sousa, Conceicao Ferreira, Vincenso Petrarca, Virgilio do E Rosario Malaria Journal 2003, 2:9 (7 May 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Much is still unknown about the ecology of malaria vectors. This paper gives a thoughtful account of the first days of imaginal bionomics of the mosquito female.

63.

459
Accesses

Research   Open Access

Limited sequence polymorphisms of four transmission-blocking vaccine candidate antigens in Plasmodium vivax Korean isolates

Jung-Mi Kang, Hye-Lim Ju, Sung-Ung Moon, Pyo-Yun Cho, Young-Yil Bahk, Woon-Mok Sohn, Yun-Kyu Park, Seok Cha, Tong-Soo Kim, Byoung-Kuk Na Malaria Journal 2013, 12:144 (30 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Malaria transmission-blocking vaccines have been regarded as useful strategy towards malaria elimination. In this study, genetic diversity of four candidate antigens(Pvs25, Pvs28, Pvs48/45, and PvWARP) were analysed in Korean isolates. Limited sequence polymorphisms of these candidate antigens provide baseline information for developing an effective vaccine malaria based on these antigens.

64.

458
Accesses

Research   Open Access Highly Accessed

Artemisinin resistance in rodent malaria - mutation in the AP2 adaptor μ-chain suggests involvement of endocytosis and membrane protein trafficking

Gisela Henriques, Axel Martinelli, Louise Rodrigues, Katarzyna Modrzynska, Richard Fawcett, Douglas R Houston, Sofia T Borges, Umberto d’Alessandro, Halidou Tinto, Corine Karema, Paul Hunt, Pedro Cravo Malaria Journal 2013, 12:118 (5 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In the rodent malaria parasite Plasmodium chabaudi, an increased artemisinin-resistant phenotype occurs along with a mutation in a functional element of the AP2 adaptor protein complex. This suggests that endocytosis and trafficking of membrane proteins may be involved, generating new insights into possible mechanisms of resistance.

65.

449
Accesses

Research   Open Access Highly Accessed

A dynamic model of some malaria-transmitting anopheline mosquitoes of the Afrotropical region. II. Validation of species distribution and seasonal variations

Torleif M Lunde, Meshesha Balkew, Diriba Korecha, Teshome Gebre-Michael, Fekadu Massebo, Asgeir Sorteberg, Bernt Lindtjørn Malaria Journal 2013, 12:78 (25 February 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Validation of a mathematical model described earlier. Overall, the model gives a realistic representation of seasonal and year-to-year variability in mosquito densities and it can accurately predict the distribution of An. gambiae s.s. and An. arabiensis in sub-Saharan Africa. It may be used for seasonal and long-term predictions of changes in the burden of malaria.

66.

448
Accesses

Case study   Open Access Highly Accessed

Experience and challenges from clinical trials with malaria vaccines in Africa

Grace Mwangoka, Bernhards Ogutu, Beverly Msambichaka, Tutu Mzee, Nahya Salim, Shubis Kafuruki, Maxmillian Mpina, Seif Shekalaghe, Marcel Tanner, Salim Abdulla Malaria Journal 2013, 12:86 (4 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The paper provides an important insight from an African research centre about lessons learned after an era of clinical trials experience. It touches upon very important issues such as sustainability of capacity built, among others.

67.

441
Accesses

Research   Open Access Highly Accessed

Plants traditionally prescribed to treat tazo (malaria) in the eastern region of Madagascar

Milijaona Randrianarivelojosia, Valérie T Rasidimanana, Harison Rabarison, Peter K Cheplogoi, Michel Ratsimbason, Dulcie A Mulholland, Philippe Mauclère Malaria Journal 2003, 2:25 (24 July 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This is a useful contribution to the study of Madagascan medicinal plants, which shows care and sensitivity in collecting the ethnobotanical data.

68.

443
Accesses

Case study   Open Access Highly Accessed

Progress towards malaria elimination in Sabang Municipality, Aceh, Indonesia

Herdiana Herdiana, Anis Fuad, Puji BS Asih, Siti Zubaedah, Risalia Reni Arisanti, Din Syafruddin, Hari Kusnanto, Maria Endang Sumiwi, Titik Yuniarti, Ali Imran, Rahmadyani Rahmadyani, Muhammad Yani, Rita Kusriastuti, Siti Nadia Tarmizi, Ferdinand J Laihad, William A Hawley Malaria Journal 2013, 12:42 (30 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

An important article outlining the progress made towards malaria elimination in Sabang municipality, Aceh, Indonesia. The details of this article will serve as an example to much of the rest of Indonesia, as well as the rest of SE Asia.

69.

440
Accesses

Research   Open Access Highly Accessed

Intermittent preventive treatment of malaria during pregnancy: a qualitative study of knowledge, attitudes and practices of district health managers, antenatal care staff and pregnant women in Korogwe District, North-Eastern Tanzania

Godfrey Mubyazi, Paul Bloch, Mathias Kamugisha, Andrew Kitua, Jasper Ijumba Malaria Journal 2005, 4:31 (20 July 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The paper provides a qualitative analysis of the programmatic issues faced when implementing IPT during pregnancy, from both provider and user perspectives. Of particular interest is the Tanzanian experience of the specific link made between SP-IPT and Steven Johnson¿s Syndrome by pregnant women, which is unique and has been one of the most important barriers to the effective uptake of ITP, as a result of media spin. The paper highlights the need for much greater attention to awareness creation among pregnant women, which is all too often an afterthought to the delivery of IPT.

70.

441
Accesses

Research   Open Access Highly Accessed

Prospective malaria control using entomopathogenic fungi: comparative evaluation of impact on transmission and selection for resistance

Penelope A Lynch, Uwe Grimm, Matthew B Thomas, Andrew F Read Malaria Journal 2012, 11:383 (22 November 2012)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

The authors compare the effectiveness of entomopathogenic fungi as a biological control tool with conventional pesticides by means of a model that consists of a mosquito feeding component and a mosquito population component.

71.

433
Accesses

Review   Open Access Highly Accessed

Costs and cost-effectiveness of malaria control interventions - a systematic review

Michael T White, Lesong Conteh, Richard Cibulskis, Azra C Ghani Malaria Journal 2011, 10:337 (3 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

This paper covers a systematic review on the costs and cost-effectiveness of malaria control interventions. The interventions covered include insecticide-treated bed nets Indoor residual spraying and Intermittent preventative treatment, diagnostic testing and appropriate treatment.

72.

435
Accesses

Opinion   Open Access Highly Accessed

Entomological surveillance of behavioural resilience and resistance in residual malaria vector populations

Nicodem J Govella, Prosper P Chaki, Gerry F Killeen Malaria Journal 2013, 12:124 (11 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

In this opinion piece, the authors indicate that caution should be exercised before over-interpreting most existing reports of increased frequency of behavioural traits which enable mosquitoes to evade fatal contact with insecticides: this may simply be the result of suppressing the most behaviourally vulnerable of the vector taxa that constituted the original transmission system.

73.

432
Accesses

Commentary   Open Access

Fulani show decreased susceptibility to Plasmodium falciparum infection versus Mossi: data from a community-wide screening and treatment of asymptomatic carriers in Burkina Faso

Alfred B Tiono, Sodiomon B Sirima, Kamal Hamed Malaria Journal 2013, 12:163 (16 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

This study confirmed that, in the same environment, individuals belonging to the Fulani ethnic group have a lower susceptibility to Plasmodium falciparum infection than Mossi individuals.

74.

430
Accesses

Research   Open Access

The decline of malaria in Finland – the impact of the vector and social variables

Lena Hulden, Larry Hulden Malaria Journal 2009, 8:94 (7 May 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Indigenous malaria in Finland faded out evenly in the whole country over the past 200 years with limited or no counter-measures or medication. It appears that malaria in Finland was basically a social disease and that malaria trends were strongly linked to changes in human behaviour.

75.

421
Accesses

Research   Open Access Highly Accessed

Reliable enumeration of malaria parasites in thick blood films using digital image analysis

John A Frean Malaria Journal 2009, 8:218 (23 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

This paper describes the definition and evaluation of a computer-based imaging algorithm for enumeration of malaria parasites in thick films. While still a long way to go from routine use, the accuracy afforded by the technique may be relevant for clinical studies of vaccines or drugs

76.

413
Accesses

Meeting report   Open Access Highly Accessed

Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of September 2012 meeting

WHO Malaria Policy Advisory Committee and Secretariat Malaria Journal 2012, 11:424 (19 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This article provides a summary of the discussions, conclusions and recommendations from the second meeting of the WHO Malaria Policy Advisory Committee

77.

411
Accesses

Review   Open Access Highly Accessed

Best practices for an insecticide-treated bed net distribution programme in sub-Saharan eastern Africa

Alexis R Sexton Malaria Journal 2011, 10:157 (8 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This review assessed literature on recent insecticide-treated bed net distribution programmes throughout sub-Saharan Eastern Africa. Forty-two studies were identified and reviewed. Studies revealed consistent inequities between urban and rural populations; which were most effectively alleviated through a free insecticide-treated bed net delivery and distribution framework

78.

407
Accesses

Research   Open Access Highly Accessed

Changes in malaria morbidity and mortality in Mpumalanga Province, South Africa (2001- 2009): a retrospective study

Lindokuhle Ngomane, Christiaan de Jager Malaria Journal 2012, 11:19 (13 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This paper provides an interesting descriptive review of nine years (eight malaria seasons) of routine malaria data from Mpumalanga Province, South Africa.

79.

407
Accesses

Research   Open Access Highly Accessed

A dynamic model of some malaria-transmitting anopheline mosquitoes of the Afrotropical region. I. Model description and sensitivity analysis

Torleif Markussen Lunde, Diriba Korecha, Eskindir Loha, Asgeir Sorteberg, Bernt Lindtjørn Malaria Journal 2013, 12:28 (23 January 2013)

Abstract | Provisional PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This study highlights some of the assumptions commonly used when constructing mosquito-malaria models and presents a realistic model of Anopheles gambiae s.s. and Anopheles arabiensis, and their interaction. The authors make a case that this new mosquito model, OMaWa, may improve the understanding of vector dynamics, which in turn can be used to better understand the dynamics of malaria.

80.

407
Accesses

Research   Open Access Highly Accessed

Successful field trial of attractive toxic sugar bait (ATSB) plant-spraying methods against malaria vectors in the Anopheles gambiae complex in Mali, West Africa

Günter C Müller, John C Beier, Sekou F Traore, Mahamoudou B Toure, Mohamed M Traore, Sekou Bah, Seydou Doumbia, Yosef Schlein Malaria Journal 2010, 9:210 (21 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This study in Mali shows that even a single application of ATSB can substantially decrease malaria vector population densities and longevity. It is likely that ATSB methods can be used as a new powerful tool for the control of malaria vectors, particularly since this approach is highly effective for mosquito control, technologically simple, inexpensive, and environmentally safe.

81.

406
Accesses

Review   Open Access Highly Accessed

Management of imported malaria in Europe

Helena H Askling, Fabrice Bruneel, Gerd Burchard, Francesco Castelli, Peter L Chiodini, Martin P Grobusch, Rogelio Lopez-Vélez, Margaret Paul, Eskild Petersen, Corneliu Popescu, Michael Ramharter, Patricia Schlagenhauf, on behalf of the European Society for Clinical Microbiology and Infectious Diseases Study Group on Clinical Parasitology Malaria Journal 2012, 11:328 (17 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A very comprehensive review on imported malaria and recommendation for its management.

82.

399
Accesses

Research   Open Access

Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model

Jérome Dormoi, Sébastien Briolant, Camille Desgrouas, Bruno Pradines Malaria Journal 2013, 12:127 (15 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Evaluation of methylene blue (MB) alone, atorvastatin (AVA) alone, and MB plus AVA in mice infected with the Plasmodium berghei ANKA strain.The in vitro synergism observed between MB and AVA suggests a potential for combination therapy.

83.

403
Accesses

Research   Open Access Highly Accessed

Malaria epidemiology in Lihir Island, Papua New Guinea

Oriol Mitjà, Raymond Paru, Billy Selve, Inoni Betuela, Peter Siba, Elisa De Lazzari, Quique Bassat Malaria Journal 2013, 12:98 (15 March 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Report on malaria epidemiology on Lihir Island, PNG, before and after a malaria control intervention carried out by the local gold mining company. An integrated vector control intervention was put in place in the villages within the mining area only.

84.

398
Accesses

Opinion   Open Access Highly Accessed

Malaria in infants aged less than six months - is it an area of unmet medical need?

Umberto D’Alessandro, David Ubben, Kamal Hamed, Serign Jawo Ceesay, Joseph Okebe, Makie Taal, Eugene Kaman Lama, Moussa Keita, Lamine Koivogui, Alain Nahum, Kalifa Bojang, Aja Adam Jagne Sonko, Honorat Francis Lalya, Bernard Brabin Malaria Journal 2012, 11:400 (2 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Review covering several issue relating to malaria in young infants, including difficulties in diagnosing the infection in this age group, uncertainty as to the burden of disease in young infants, and optimal treatment and prevention (currently anti-malarial use in this age group is current ¿off-label¿).

85.

400
Accesses

Research   Open Access Highly Accessed

Rapid diagnostic tests for molecular surveillance of Plasmodium falciparum malaria -assessment of DNA extraction methods and field applicability

Ulrika Morris, Berit Aydin-Schmidt, Delér Shakely, Andreas Mårtensson, Louise Jörnhagen, Abdullah S Ali, Mwinyi I Msellem, Max Petzold, José P Gil, Pedro E Ferreira, Anders Björkman Malaria Journal 2013, 12:106 (19 March 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

The paper compares different methods for extracting genomic DNA from used malaria RDTs for subsequent molecular analysis. Overall, the study provides useful information for those undertaking epidemiological studies and carrying out surveillance of anti-malarial resistance.

86.

394
Accesses

Case study   Open Access Highly Accessed

Misclassification of Plasmodium infections by conventional microscopy and the impact of remedial training on the proficiency of laboratory technicians in species identification

Peter Obare, Bernhards Ogutu, Mohammed Adams, James Sande Odera, Ken Lilley, David Dosoo, Christine Adhiambo, Seth Owusu-Agyei, Fred Binka, Elizabeth Wanja, Jacob Johnson Malaria Journal 2013, 12:113 (27 March 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

The major problem related to microscopy for malaria diagnosis is the quality of the training of microscopists. This work explores misclassifications of four Plasmodium species by conventional microscopy in relation to the proficiency of microscopists and morphological characteristics of the parasites on Giemsa-stained blood films.

87.

393
Accesses

Research   Open Access

Effect of malaria in pregnancy on foetal cortical brain development: a longitudinal observational study

Marcus J Rijken, Merel de Wit, Eduard JH Mulder, Suporn Kiricharoen, Noaeni Karunkonkowit, Tamalar Paw, Gerard HA Visser, Rose McGready, François H Nosten, Lourens R Pistorius Malaria Journal 2012, 11:222 (2 July 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The authors studied brain development, using a portable ultrasound machine and a 3D ultrasound transducer, in foetuses of mothers with treated malaria as compared to control mother without malaria. They were not able to found significant differences in terms of supratentorial brain volume or delay in sulcation.

88.

391
Accesses

Research   Open Access Highly Accessed

Prevalence of congenital malaria in high-risk Ghanaian newborns: a cross-sectional study

Christabel C Enweronu-Laryea, George O Adjei, Benjamin Mensah, Nancy Duah, Neils B Quashie Malaria Journal 2013, 12:17 (11 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A very interesting study of two populations of newborns - one in a neonatal intensive care unit, the other studied during the first week of life. The paper was able to address an important question: how often are newborns at risk of dying from congenital malaria? The answer is, rarely.

89.

387
Accesses

Opinion   Open Access Highly Accessed

Roll Back Malaria? The scarcity of international aid for malaria control

Vasant Narasimhan, Amir Attaran Malaria Journal 2003, 2:8 (15 April 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

This provocative paper outlines how the failure of governments and funding agencies to honour the promises of financial support of the Abuja Declaration risks ultimately to have a negative impact on the RBM programme.

90.

382
Accesses

Review   Open Access Highly Accessed

Primaquine in vivax malaria: an update and review on management issues

Deepika Fernando, Chaturaka Rodrigo, Senaka Rajapakse Malaria Journal 2011, 10:351 (12 December 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Paper reviews the published literature on the use of primaquine as an agent for prophylaxis and radical cure. The detailed section on G6PD deficiency as a barrier for mass administration of primaquine and the section on the use of primaquine with blood schizontocidals other than chloroquine is useful.

91.

380
Accesses

Research   Open Access

Evaluation of the 2011 long-lasting, insecticide-treated net distribution for universal coverage in Togo

Elizabeth R Stevens, Abigail Aldridge, Yawo Degbey, Akou Pignandi, Monique A Dorkenoo, Justin Hugelen-Padin Malaria Journal 2013, 12:162 (16 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Description of a largely successful campaign to distribute LLINs to all age-groups across Togo. The authors conclude that even though the campaign was unable to achieve the universal coverage target, it rapidly increased overall coverage and was far better than previous campaigns that targeted only pregnant women and under fives.

92.

367
Accesses

Review   Open Access Highly Accessed

Challenges in using geographic information systems (GIS) to understand and control malaria in Indonesia

Neil G Sipe, Pat Dale Malaria Journal 2003, 2:36 (4 November 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Most studies on the use of GIS for malaria control have been performed in Africa and the application of the technique in Indonesia raised important issues. This comprehensive review looks at the limitations of GIS and how best to solve various problems to make this approach more user-friendly.

93.

367
Accesses

Methodology   Open Access Highly Accessed

A new double-antibody sandwich ELISA targeting Plasmodium falciparum aldolase to evaluate anti-malarial drug sensitivity

Lucienne Tritten, Hugues Matile, Reto Brun, Sergio Wittlin Malaria Journal 2009, 8:226 (12 October 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In their paper, the authors report the use of a newly developed aldolase ELISA for drug sensitivity testing in P. falciparum. The new assay adds to the panel of available ELISA-based malaria drug sensitivity assays.

94.

367
Accesses

Research   Open Access Highly Accessed

Community knowledge, attitudes and practices (KAP) on malaria in Swaziland: A country earmarked for malaria elimination

Khumbulani W Hlongwana, Musawenkosi LH Mabaso, Simon Kunene, Dayanandan Govender, Rajendra Maharaj Malaria Journal 2009, 8:29 (19 February 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Despite fair knowledge of malaria in Swaziland, there is a need for improving the availability of information through the preferred community channels, such as the traditional community district meetings or tinkhundlas. There is documented evidence suggesting that as the level transmission and disease decreases, so does the perception about the importance of malaria control activities.

95.

364
Accesses

Methodology   Open Access Highly Accessed

Estimating malaria parasite density: assumed white blood cell count of 10,000/μl of blood is appropriate measure in Central Ghana

Dennis Adu-Gyasi, Mohammed Adams, Sabastina Amoako, Emmanuel Mahama, Maxwell Nsoh, Seeba Amenga-Etego, Frank Baiden, Kwaku Asante, Sam Newton, Seth Owusu-Agyei Malaria Journal 2012, 11:238 (23 July 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Analysis of the use of an assumed WBC count compared to the actual WBC for estimating parasitaemia in children aged 0-5 years in Ghana. Questioning the accuracy of this widely used method for estimating malaria parasitaemia is an important research topic since it is commonly used to guide important policy and practice decisions.

96.

358
Accesses

Research   Open Access Highly Accessed

Malaria in pregnant women in an area with sustained high coverage of insecticide-treated bed nets

Abdunoor M Kabanywanyi, John R MacArthur, Wilma A Stolk, J Dik F Habbema, Hassan Mshinda, Peter B Bloland, Salim Abdulla, S Patrick Kachur Malaria Journal 2008, 7:133 (21 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This study of a group of pregnant women who have not taken IPTp with SP during their pregnancy shows that malaria remains a problem even in an area with high bed net coverage.

97.

355
Accesses

Research   Open Access Highly Accessed

Detection of malaria parasites by nested PCR in south-eastern, Iran: Evidence of highly mixed infections in Chahbahar district

Sedigheh Zakeri, Sohaila Najafabadi, Ahmad Zare, Navid Djadid Malaria Journal 2002, 1:2 (8 February 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

98.

354
Accesses

Commentary   Open Access Highly Accessed

Discourse on malaria elimination: where do forcibly displaced persons fit in these discussions?

Holly A Williams, Heiko Hering, Paul Spiegel Malaria Journal 2013, 12:121 (10 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

The paper discusses the important issue of displaced persons in malaria control - a thought provoking document.

99.

355
Accesses

Review   Open Access Highly Accessed

Statics and dynamics of malaria infection in Anopheles mosquitoes

David L Smith, F Ellis McKenzie Malaria Journal 2004, 3:13 (4 June 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This theoretical and mathematical review provides a new look at the Ross-Macdonald models, the basis of malaria epidemiology. The models describe the processes that drive malaria transmission, mainly from an entomological perspective, and they are, therefore, particularly useful to evaluate intervention programmes that reduce transmission.

100.

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Methodology   Open Access Highly Accessed

Optimization of flow cytometric detection and cell sorting of transgenic Plasmodium parasites using interchangeable optical filters

Ivan A Vorobjev, Kathrin Buchholz, Prashant Prabhat, Kenneth Ketman, Elizabeth S Egan, Matthias Marti, Manoj T Duraisingh, Natasha S Barteneva Malaria Journal 2012, 11:312 (5 September 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

This manuscript providesinteresting and useful information for all those malaria researchers who use transfected (especially GFP) parasites, in that it provides some information on how to improve the flow cytometric detection of these parasites.

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