- Marcel Hommel, University of Liverpool
ResearchDescribes anti-malarial activity of tigecycline, a new derivative of tetracycline class of antibiotics, showing promising activityin vitro and in vivo in combination with CQ.
ResearchAn interesting study which contributes to better understanding of biological and epidemiological aspects of malaria infection in chimpanzees.Research provides evidence that susceptibility to malaria infection increases during chimpanzee pregnancy and addresses a substantial question on chimpanzee populations' fitness and conservation.
MethodologyDevelopment of a flow cytometry assay to quantify infected red cells in the presence of leukocytes and capable of discriminating between life/dead cells. The authors show that the assay does better than previously developed assays when it comes to discriminating early ring stages from uninfected red cells.
ResearchComparaison of he accuracy of malaria diagnosis by microscopy with real-time PCR. Based on SYBR Green PCR: a high frequency of mixed P. falciparum/P. vivax infections and P. ovale infections was observed that had been missed by microscopy.
ResearchCompares the antibody levels to two recombinant P. falciparum antigens (MSP1-19 and PF13, the DBL1a domain of PfEMP1 variant PF13-0003) using standard ELISA and the multiplex Magpix-Luminex assay.
ResearchThe paper describes a study of the radical curative activity of mirincamycin, a clindamycin analog, in the P. cynomolgi-rhesus monkey model. While causal prophylactic activity was observed in the mouse model, radical curative activity was not observed in small test groups of primates.
Aims & scope
Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialities involved in this very broad discipline, from the bench to the bedside and to the field. Malaria Journal offers a fast publication schedule while maintaining rigorous peer-review; this is achieved by managing the whole of the publication process electronically, from submission to peer-review.
Malaria Journal 2014, 13:400
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Volume 13 Suppl 1 (22 September 2014)
Oxford, UK. 22-24 September 2014