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| Editor-in-Chief: Marcel Hommel, University of Liverpool
Latest supplement
Volume 8 Suppl 1
Reviews
Latest articles
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Research
Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells
Nadine Fievet, Stefania Varani, Samad Ibitokou, Valerie Briand, Stephanie Louis, Rene-Xavier Perrin, Achille Massougbodji, Anne Hosmalin, Marita Troye-Blomberg, Philippe Deloron
Malaria Journal 2009, 8:251 (5 November 2009)
[Abstract] [Provisional PDF]
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The findings support the view that placental parasitization is significantly associated with partial maturation of different dendritic cell subsets and also to slightly increased responses to TLR9 ligand in cord blood
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Research
Comparison of Plasmodium falciparum allelic frequency distribution in different endemic settings by high-resolution genotyping
Sonja Schoepflin, Francesca Valsangiacomo, Enmoore Lin, Benson Kiniboro, Ivo Mueller, Ingrid Felger
Malaria Journal 2009, 8:250 (30 October 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]
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A description of allele frequencies of two polymorphic P. falciparum surface antigens from two sites of varying transmission intensity, Papua New Guinea and Tanzania. It confirms previous reports of a higher mean multiplicity of infection and increased genetic diversity in areas of higher endemicity.
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Research
Human Plasmodium knowlesi infections in young children in central Vietnam
Peter Van den Eede, Hong Nguyen Van, Chantal Van Overmeir, Indra Vythilingam, Thang Ngo Duc, Le Xuan Hung, Hung Nguyen Manh, Jozef Anné, Umberto D'Alessandro, Annette Erhart
Malaria Journal 2009, 8:249 (30 October 2009)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]
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Three of 95 samples from Vietnamese people believed to be infected with P. malariae were also positive for P. knowlesi by PCR. These findings extend the number of countries in Southeast Asia with reports of human P. knowlesi infections.
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Research
Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts
Wim Van Bortel, Vu Duc Chinh, Dirk Berkvens, Niko Speybroeck, Ho Dinh Trung, Marc Coosemans
Malaria Journal 2009, 8:248 (29 October 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]
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This paper describes the results of experimental hut trials to investigate the efficacy of a variety of insecticide-treated nets. The local vector population is partially resistant to multiple pyrethroid insecticides and so the rational behind the study was to determine whether the nets were still effective against resistant mosquitoes.
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Research
The malaria candidate vaccine liver stage antigen-3 is highly conserved in Plasmodium falciparum isolates from diverse geographical areas
Eric Prieur, Pierre Druilhe
Malaria Journal 2009, 8:247 (29 October 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]
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The paper compares the sequences of LSA-3 from four geographical areas and found LSA-3 to be a highly conserved antigen. This finding further supports the usefulness of LSA-3 as a pre-erythrocytic stage vaccine candidate.
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Plasmodium life-cycle and natural history of malaria
This animation, which illustrates, in six short sequences, the various stages of the life-cycle of the malaria parasite in the human host and in its mosquito vector, has been conceived by Professors Christophe Rogier et Marcel Hommel.
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