- Marcel Hommel, University of Liverpool
- Elizabeth Ashley, Mahidol Oxford Tropical Medicine Research Unit
- Ulrike Fillinger, London School of Hygiene and Tropical Medicine
- Simon Hay, IHME, University of Washington
- Caroline Jones, London School of Hygiene & Tropical Medicine
- Didier Leroy, Medicines for Malaria Venture
- Georges Snounou, Universite Pierre & Marie Curie
- Marcel Tanner, Swiss Tropical Institute
ResearchDescribes the optimization of a colourimetric LAMP assay. The assay was tested on samples originating in different endemic settings with different species compositions, and also tested in a field setting in Malaysia. Even if not strictly-speaking high throughput and/or field applicable, the methodology is an important addition to the battery of sensitive diagnostic tools that will be needed.
ResearchThe mechanism and timing of commitment to gametocytogenesis is still not fully elucidated. The characterization of PfGEXP5 as a marker for early ring stage parasites committed to the sexual development pathway as detailed in this paper will make a useful addition to the small battery of markers currently available and will be a valuable tool with which to study gametocyte biology in the laboratory and field.
ResearchA study involving 13,299 subjects from 10 sites in Africa and Asia, genotyped for 178 SNPs and tested for association with antibodies to four malarial antigens and total IgE levels. The authors' most significant finding is to identify an association between sickle cell trait and reduced antibody concentrations to blood-stage antigens.
ResearchThe relationship between LLIN integrity and efficacy needs to be understood in order to guide LLIN distribution policy. Badly torn nets that still contain insecticide have still the potential to reduce malaria transmission. This paper contains very interesting results regarding the interplay of hole area, hole size, and resistance in vector populations on the efficacy of LLINs.
ResearchDescribes prescription practice of anti-malarial treatments in second level health care in Uganda. Data were collected through a reinforced surveillance system with the aim to highlight whether prescription practice had changed after the Ugandan Ministry of Health adopted two new WHO recommendations: the replacement of presumptive treatment with a parasitological diagnosis, and the replacement of intravenous quinine with intravenous artesunate.
ResearchA further validation of 6 Plasmodium vivax genotyping markers. The authors show that, depending on the type of marker used for P. vivax analysis, a considerable amplification bias is observed, which may compromise the characterization of multi-clonal P. vivax infections.
Aims & scope
Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialities involved in this very broad discipline, from the bench to the bedside and to the field. Malaria Journal offers a fast publication schedule while maintaining rigorous peer-review; this is achieved by managing the whole of the publication process electronically, from submission to peer-review.
Malaria Journal 2015, 14:289
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Edited by: Dr. Julian Eckl, Dr. Susanna Hausmann Muela
Published: 24 April 2015
Last updated: 24 June 2015
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Published: 23 April 2015
Last updated: 24 April 2015