- Marcel Hommel, University of Liverpool
ResearchIn vitro and in vivo antiplasmodial activities of Himatanthus articulatus, as well as the toxicity assessment of its crude ethanolic extract.
ResearchAt a time where donors, researchers and policy-makers claim that ACT has significantly contributed to the decline of malaria in Africa, a finding that less than 25% of those prescribing and distributing ACT in Sudan know what they are doing, is alarming and, obviously, needs to be improved.
ResearchSporozoite immunization of animals and humans under a chemo-prophylactic cover of chloroquine efficiently induces sterile protection against malaria. In humans, this is strikingly more efficient than immunization with radiated attenuated sporozoites and the authors hypothesized that this might be partially due to chloroquine. The data do not provide evidence for a direct beneficial effect of chloroquine.
ResearchDetailed molecular analysis of the pfcrt, pfmdr1 and pfNHE alleles in samples from children being followed in the Mother-Offspring Malaria study in Muheza, Tanzania in 2003-2006.
ResearchSplenic response of Saimiri sciureus monkeys to infection with Plasmodium falciparum infection. During the acute phase of infection, splenic disarray with disorganized germinal centres was observed. During convalescence, spleens of the chloroquine-treated animals showed white pulp hyperplasia with extensive lymphocyte activation.
ResearchThis study aimed at determining the active pharmaceutical ingredient content of anti-malarial medicines available in Malawi with respect to the manufacturers¿ label claim and pharmacopoeia specifications. Results show the presence of both excessive and insufficient artemisinin-based and non-artemisinin-based ingredients, pointing to poor adherence to GMP and improper handling during storage or distribution.
Aims & scope
Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialities involved in this very broad discipline, from the bench to the bedside and to the field. Malaria Journal offers a fast publication schedule while maintaining rigorous peer-review; this is achieved by managing the whole of the publication process electronically, from submission to peer-review.