- Marcel Hommel, University of Liverpool
ResearchProteins secreted from the rhoptry in merozoites are associated with the formation of tight junctions and parasitophorous vacuoles during invasion of erythrocytes and are stored within the rhoptry neck or bulb. This study analysed the antigenicity and immunogenicity of PvRALP1, suggesting that PvRALP1 may be immunogenic in humans and might play an important role during invasion of P. vivax parasites.
ReviewThe hyper-reactive malarial splenomegaly syndrome is caused by a chronic antigenic stimulation derived from the malaria parasite and is a leading cause of massive splenomegaly in malaria-endemic countries. This systematic review of the literature focuses on case definition, epidemiology and management.
ResearchA comprehensive field study of the effects of a prototype push-pull system, whereby spatial repellents are used in combination with outdoor baited traps. The intervention was evaluated using an experimental hut methodology to test proof-of-principle for the strategy against two natural vector populations in Belize, Central America.
ResearchThe aim of this study was to assess the effects of paradoxical sleep deprivation and sleep rebound on Plasmodium chabaudi infection in mice. Paradoxical sleep deprivation is damaging to the immune system and leads to an increased level and increased severity.
Case studyControlled human malaria infection models are a critical component in the development of vaccines, drugs and diagnostics for the disease. They speed the development of products, aid in downselecting ineffective and unsafe products, and expand the understanding of the immunology of malaria. It was important getting this established in Kenya.
ResearchResearchers challenge the bromeliad malaria paradigm that argues that P. vivax persists at low prevalence in the Atlantic Forest ecosystem due to life history of the parasite and the bionomics of the dominant mosquito vector in the region. The data the authors present contributes towards a better understanding of this system.
Aims & scope
Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialities involved in this very broad discipline, from the bench to the bedside and to the field. Malaria Journal offers a fast publication schedule while maintaining rigorous peer-review; this is achieved by managing the whole of the publication process electronically, from submission to peer-review.
Malaria Journal 2015, 14:177
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Edited by: Dr. Susanna Hausmann Muela, Dr. Julian Eckl
Published: 24 April 2015
Every day is Malaria Day
Published: 23 April 2015
Last updated: 24 April 2015