Additional file 1.

Comparison of the effects of three anti-PMN monoclonal antibodies. (A) Peripheral blood parasitaemia in 3 different NOD/SCID mice treated either with NIMP-R14 (plain circle, dotted line), RB6-8C5 (open circle) or 1A8 (black square) monoclonal antibody at 10 mg/kg. Black arrows represent injection of HuRBC + clo-clip and one of the three anti-PMN antibodies. (B) Peritoneal blood parasitaemia obtained in the NOD/SCID mice treated with different anti-PMN. (C) Percentages of CD11b⁺ Ly-6G⁺ PMN in mouse peripheral blood following repeated administration of the anti-PMN monoclonal antibodies.

Format: PDF Size: 1.5MB Download file

This file can be viewed with: Adobe Acrobat Reader

Arnold et al. Malaria Journal 2010 9:197   doi:10.1186/1475-2875-9-197