Figure 3.

Cellular responses to wildtype-MSP1₁₉ antigen and the two variants with four amino acid substitutions. 27+31+34+43 and 15+27+31+43 MSP1₁₉ variants in 5 individuals of different ages and malaria exposure. OM21 and OM08 had clinical presentation but the others did not. The stimulation indices (SI) for the 27+31+34+43 (dotted boxes) and 15+27+31+43 (shaded box) variants were significantly higher than the SI for the WT-MSP1₁₉ antigen (clear boxes).