Case report
Invasive Aspergillus fumigatus infection after Plasmodium falciparum malaria in an immuno-competent host: Case report and review of literature
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* Corresponding author: Isabella Eckerle isabella.eckerle@med.uni-heidelberg.de
1 Section Clinical Tropical Medicine, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Heidelberg, Germany
2 Internal Medicine IV, University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
3 Department of Pulmonology and Critical Care Medicine, Thoraxklinik, Amalienstraße 5, 69126 Heidelberg, Germany
4 Institute of Pathology, University Heidelberg, Im Neuenheimer Feld 220/221, 69120, Heidelberg, Germany
Malaria Journal 2009, 8:167 doi:10.1186/1475-2875-8-167
Published: 20 July 2009Abstract
Invasive fungal infection is rarely reported in association with malaria, even though malaria-associated inhibition of phagocyte function is a well-known condition. Invasive aspergillosis is frequently found in severely immuno-compromised patients but not in healthy individuals. Here, a case of pulmonary invasive aspergillosis in a previously healthy patient with severe P. falciparum malaria is presented, who was successfully treated with voriconazol and caspofungin. This is the first survival of malaria-associated invasive aspergillosis.