Table 2

Laboratory markers of malaria disease severity


n (%)







Pre
Post
PR* [95% CI]
chi-squared
p-value

Slide-positive (N = 386)
205 (80.4)
63 (48.1)
1.67 [1.39–2.02]
<0.0001
Suspected malaria, no slide results available (N = 51)
32 (11.1)
19 (12.7)
0.88 [0.52–1.50]
0.64
High parasitaemia (N = 268)
116 (56.6)
22 (34.9)
1.62** [1.11–2.38]
0.004
Severe anemia, slide-positive admissions (N = 161)
21 (18.9)
4 (8.0)
2.47** [0.84–7.24]
0.08
Severe anemia, all hospitalizations (N = 307)
23 (15.3)
6 (3.8)
3.85** [1.60–9.25]
0.001
No hemoglobin result (N = 244)
172 (53.4)
72 (31.4)
1.70 [1.37–2.11]
<0.0001

Results for laboratory-definable markers of disease severity: admission haemoglobin and admission peripheral parasitaemia are shown. For parasitaemia, percents are recorded as proportion of pre-intervention, post-intervention, or total admissions for malaria for which a slide result was available. For low vs. high (3+-4+) parasitaemia, percents are recorded as proportion of total slide-positive malaria admissions. For missing data, percentages are recorded as proportion of total malaria admissions for which slide results were unavailable. Severe anemia is defined as ≤ 5 g/dl. * Prevalence ratio comparing the proportion in the pre-intervention period to the proportion in the post-intervention period. ** adjusted for age using three categories (<1 year; 1–5 years; > 5 years)

Sievers et al. Malaria Journal 2008 7:167   doi:10.1186/1475-2875-7-167

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