Table 3 |
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|
Efficacy of antimicrobial preservation of the artemisinin-derivative reconstituted suspensions |
|||||||||
| pH wet suspension |
Preservative |
P. aeruginosa |
S. aureus |
E. coli |
C. albicans |
Z. rouxii |
A. niger |
Ph. Eur. requirements |
|
|
|
|||||||||
| Artenam® |
4.50 |
Sorbic acid |
- |
- |
- |
- |
- |
- |
Conforms |
| Gvither® |
4.30 |
MP/PP |
- |
- |
- |
- |
- |
- |
Conforms |
| Artesiane® |
5.43 |
MP/PP |
- |
- |
- |
- |
- |
+ |
Does not conform |
| Alaxin® |
4.40 |
MP/PP |
- |
+ |
- |
- |
- |
+ |
Does not conform |
| Artexin® |
5.90 |
Benzoic acid |
+ |
- |
+ |
- |
- |
- |
Does not conform |
| Santecxin® |
5.55 |
Benzoic acid |
+ |
- |
+ |
+ |
+ |
+ |
Does not conform |
| Cotecxin® |
not tested |
Chlorbutanol? |
- |
- |
+ |
+ |
+ |
+ |
Does not conform |
|
|
|||||||||
|
+ = positive for the tested microorganisms, - = negative for the tested microorganisms MP = methylparaben, PP = propylparaben |
|||||||||
|
Atemnkeng et al. Malaria Journal 2007 6:12 doi:10.1186/1475-2875-6-12 |
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