Table 2

Concentration of preservative(s) in dry suspensions after reconstitution

Product/Manufacturer
Active ingredient/Dose
Preservative(s) identified
% preservative found
Normal value in H2O+ (%)

Artenam®* Arenco, Belgium
Artemether 180 mg/60 ml
Sorbic acid
0.27
0.20
Gvither® GVS Labs, India
Artemether 300 mg/100 ml
Methylparaben
0.18
0.08


Propylparaben
0.06
0.02
Artesiane® Dafra, Belgium
Artemether 300 mg/100 ml
Methylparaben
0.08
0.08


Propylparaben
0.02
0.02
Alaxin® GVS Labs, India
Dihydroartemisinin 160 mg/80 ml
Methylparaben
0.09
0.08


Propylparaben
0.01
0.02
Artexin® Sphinx Pharma, Kenya
Dihydroartemisinin 160 mg/80 ml
Benzoic acid
0.15
0.10
Santecxin® Shsj, China
Dihydroartemisinin 160 mg/80 ml
Benzoic acid
0.03
0.10
Cotecxin®, Jiaxing Nanhu Pharma, China
Dihydroartemisinin 160 mg/80 ml
Chlorbutanol?
Not tested
0.50

* Semi-industrial batch, + Source: Martindale (The Complete Drug Reference) 1999.

Atemnkeng et al. Malaria Journal 2007 6:12   doi:10.1186/1475-2875-6-12