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Open Access Highly Accessed Review

Sustainable malaria control: transdisciplinary approaches for translational applications

Lyn-Marie Birkholtz1, Riana Bornman2, Walter Focke3, Clifford Mutero24 and Christiaan de Jager2*

Author Affiliations

1 Department of Biochemistry, University of Pretoria, Private Bag x20, Pretoria, Gauteng, South Africa, 0028

2 University of Pretoria Centre for Sustainable Malaria Control (UP CSMC), University of Pretoria, Private Bag x323, Pretoria, Gauteng, South Africa, 0001

3 Department of Chemical Engineering, University of Pretoria, Private Bag x20, Pretoria, Gauteng, South Africa, 0028

4 International Centre of Insect Physiology and Ecology, P.O. Box 30772, Nairobi, Kenya, 00100

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Malaria Journal 2012, 11:431  doi:10.1186/1475-2875-11-431

Published: 26 December 2012

Abstract

With the adoption of the Global Malaria Action Plan, several countries are moving from malaria control towards elimination and eradication. However, the sustainability of some of the approaches taken may be questionable. Here, an overview of malaria control and elimination strategies is provided and the sustainability of each in context of vector- and parasite control is assessed. From this, it can be concluded that transdisciplinary approaches are essential for sustained malaria control and elimination in malaria-endemic communities.

Keywords:
Plasmodium; Anopheles; DDT; Vector control; Anti-malarial drugs