Volume 13 Supplement 1

Challenges in malaria research: Core science and innovation

Meeting abstracts

Publication of this supplement has not been supported by sponsorship.

Challanges in malaria research: Core science and innovation.

Oxford, UK22-24 September 2014

Concatenated PDF 13S1

Page 1 of 3

Phenotypic divergence among the members of the African malaria mosquitoes and strategies of persistence throughout the dry season

Authors: Tovi Lehmann, Adama Dao, Alpha S Yaro, Diana L Huestis, Moussa Diallo, Seydou Timbiné, Yaya Kassogué, Alpha Adamou, Adama I Traoré and Djibril Samaké

Citation: Malaria Journal 2014 13(Suppl 1):O2

Content type: Oral presentation Published on: 22 September 2014
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Mechanisms of reproductive isolation between incipient species in the Anopheles gambiae species complex

Authors: Roch Dabiré, Simon Sawadogo, Abdoulaye Diabaté, Hyacinthe Toé, Pierre Kengne, Ali Ouari, Carlo Costantini, Clement Gouagna, Cedric Pennetier, Frederic Simard, Thierry Baldet, Tovi Lehman and Gabriella Gibson

Citation: Malaria Journal 2014 13(Suppl 1):O4

Content type: Oral presentation Published on: 22 September 2014
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Assessing the impact of vector control interventions by measuring their effectiveness - what has been done in Madagascar

Authors: Thomas Kesteman, Milijaona Randrianarivelojosia, Patrice Piola and Christophe Rogier

Citation: Malaria Journal 2014 13(Suppl 1):O5

Content type: Oral presentation Published on: 22 September 2014
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The ins and outs of sporozoite biology in the dermis

Authors: Christine Hopp and Photini Sinnis

Citation: Malaria Journal 2014 13(Suppl 1):O6

Content type: Oral presentation Published on: 22 September 2014
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Can we stop malaria parasites in the skin?

Authors: Ross Douglas, Miriam Ester, Janina Hellmann and Friedrich Frischknecht

Citation: Malaria Journal 2014 13(Suppl 1):O7

Content type: Oral presentation Published on: 22 September 2014
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The role of genetics in the variable clinical response to different forms of malaria

Authors: David Weatherall

Citation: Malaria Journal 2014 13(Suppl 1):O8

Content type: Oral presentation Published on: 22 September 2014
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Malaria 2050: from science to strategy; from evidence to eradication

Authors: Richard Feachem

Citation: Malaria Journal 2014 13(Suppl 1):O9

Content type: Oral presentation Published on: 22 September 2014
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Review of the interactions between G6PD deficiency and primaquine therapy for malaria control and elimination

Authors: Rosalind Howes

Citation: Malaria Journal 2014 13(Suppl 1):O11

Content type: Oral presentation Published on: 22 September 2014
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Establishing a unique specimen repository with characterized G6PD enzyme activity for the development of new G6PD point-of-care tests

Authors: Maria Kahn, Nicole LaRue, Jeffrey Wellhausen, Sampa Pal and Gonzalo J Domingo

Citation: Malaria Journal 2014 13(Suppl 1):O12

Content type: Oral presentation Published on: 22 September 2014
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Epistasis and the sensitivity of phenotypic screens for beta thalassaemia

Authors: Bridget Penman, Sunetra Gupta and David Weatherall

Citation: Malaria Journal 2014 13(Suppl 1):O13

Content type: Oral presentation Published on: 22 September 2014
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Challenges in malaria modeling

Authors: F Ellis McKenzie

Citation: Malaria Journal 2014 13(Suppl 1):O14

Content type: Oral presentation Published on: 22 September 2014
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Modeling to inform strategies for malaria eradication

Authors: Steven E Kern

Citation: Malaria Journal 2014 13(Suppl 1):O15

Content type: Oral presentation Published on: 22 September 2014
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Age-shifting in malaria incidence upon cessation of interventions: a simulation study

Authors: Peter Pemberton-Ross, Katya Galactionova, Tom Smith and Melissa Penny

Citation: Malaria Journal 2014 13(Suppl 1):O16

Content type: Oral presentation Published on: 22 September 2014
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Modeling the spatio-temporal dynamics of malaria parasite population genetics

Authors: Edward Wenger, Joshua Proctor and Philip Eckhoff

Citation: Malaria Journal 2014 13(Suppl 1):O17

Content type: Oral presentation Published on: 22 September 2014
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Science and innovation in malaria diagnostics

Authors: Sanjeev Krishna

Citation: Malaria Journal 2014 13(Suppl 1):O19

Content type: Oral presentation Published on: 22 September 2014
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Persistent sub-microscopic parasitaemia after ACT treatment of African children

Authors: Colin Sutherland

Citation: Malaria Journal 2014 13(Suppl 1):O20

Content type: Oral presentation Published on: 22 September 2014
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Disentangling malaria anaemia

Authors: Kathrin Schuldt, Jennifer Evans, Julia Lenzen, Christa Ehmen, Birgit Muntau, Jurgen Sievertsen, Yeetey Enuameh, Kingsley Osei-Kwakye, Ernest Cudjoe Opoku, Edmund NL Browne, Rolf Horstmann and Christian Timmann

Citation: Malaria Journal 2014 13(Suppl 1):O21

Content type: Oral presentation Published on: 22 September 2014
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Plasmodium vivax Duffy binding protein: understanding targets of protective immunity

Authors: John H Adams, Miriam T George, Francis B Ntumngia, Jesse Schloegel, Samantha J Barnes and Amy M McHenry

Citation: Malaria Journal 2014 13(Suppl 1):O22

Content type: Oral presentation Published on: 22 September 2014
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Overcoming challenges to discover drugs for liver stages of Plasmodium vivax

Authors: Dennis E Kyle

Citation: Malaria Journal 2014 13(Suppl 1):O23

Content type: Oral presentation Published on: 22 September 2014
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Dynamics of P. vivax clones in a cohort of children with or without primaquine treatment at baseline

Authors: Rahel Wampfler, Leanne Robinson, Natalie Hofmann, Andreea Waltmann, Inoni Betuela, Mariabeth Silkey, Peter Siba, Tom Smith, Ivo Mueller and Ingrid Felger

Citation: Malaria Journal 2014 13(Suppl 1):O24

Content type: Oral presentation Published on: 22 September 2014
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Therapeutic disruption of Plasmodium vivax infected red cell deformability

Authors: Rou Zhang, Wenn-Chyau Lee, Benoit Malleret, Rossarin Suwanarusk, Ming Dao, Cindy Chu, Chwee Teck Lim, Laurent Renia, Francois Nosten and Bruce Russell

Citation: Malaria Journal 2014 13(Suppl 1):O25

Content type: Oral presentation Published on: 22 September 2014
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Measuring malaria transmission reduction en route to elimination

Authors: Richard W Steketee

Citation: Malaria Journal 2014 13(Suppl 1):O26

Content type: Oral presentation Published on: 22 September 2014
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Are investments in malaria control saving the lives of children? Challenges in using all-cause child mortality for measuring the impact of malaria control programs

Authors: Thomas Eisele

Citation: Malaria Journal 2014 13(Suppl 1):O27

Content type: Oral presentation Published on: 22 September 2014
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Insecticide-treated nets (ITNs) in Africa 2000-2016: coverage, system efficiency and future needs for achieving international targets

Authors: Samir Bhatt and Peter Gething

Citation: Malaria Journal 2014 13(Suppl 1):O29

Content type: Oral presentation Published on: 22 September 2014
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Towards a multi-antigen multi-stage malaria vaccine

Authors: Adrian VS Hill, Sumi Biswas, Simon Draper, Thomas Rampling and Arturo Reyes-Sandoval

Citation: Malaria Journal 2014 13(Suppl 1):O31

Content type: Oral presentation Published on: 22 September 2014
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Methods, markers and mechanisms for protective immunity in the controlled human malaria infection model

Authors: Robert Sauerwein

Citation: Malaria Journal 2014 13(Suppl 1):O32

Content type: Oral presentation Published on: 22 September 2014
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Controlled human malaria infection in Kenyan adults: A safe model that could accelerate assessment of novel drugs and vaccines in malaria endemic populations

Authors: Susanne Hodgson, Elizabeth Juma, Amina Salim, Charles Magiri, Domtila Kimani, Daniel Njenga, Alfred Muia, Andrew Cole, Caroline Ogwang, Peter Billingsley, Eric James, Kim Lee Sim, Thomas Rampling, Adrian Hill, Faith Osier, Simon Draper…

Citation: Malaria Journal 2014 13(Suppl 1):O33

Content type: Oral presentation Published on: 22 September 2014
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Progress with PfSPZ Vaccine, a radiation attenuated Plasmodium falciparum sporozoite vaccine

Authors: Peter Billingsley, B Kim Lee Sim, Eric James, Thomas Richie, Seif Shekalaghe, Sara Healy, Mahamadou Sissoko, Benjamin Mordmueller, Julie Ledgerwood, Barney Graham, Patrick Duffy, Robert Seder, Kirsten Lyke, Judith Epstein, Pedro Alonso, Salim Abdullah…

Citation: Malaria Journal 2014 13(Suppl 1):O34

Content type: Oral presentation Published on: 22 September 2014
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Drugs for malaria elimination: what do we have now and what do we need?

Authors: Dennis Shanks

Citation: Malaria Journal 2014 13(Suppl 1):O35

Content type: Oral presentation Published on: 22 September 2014
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A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel spiroindolone KAE609, to assess the safety, tolerability and pharmacokinetics in healthy adult volunteers

Authors: Joel Leong, Ruobing Li, Jay Prakash Jain, Gilbert Lefèvre, Baldur Magnusson, Thierry Diagana and Peter Pertel

Citation: Malaria Journal 2014 13(Suppl 1):O37

Content type: Oral presentation Published on: 22 September 2014
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Relevance of K13 mutations for malaria control and elimination program

Authors: Frédéric Ariey

Citation: Malaria Journal 2014 13(Suppl 1):O40

Content type: Oral presentation Published on: 22 September 2014
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Genomic analyses of complex P. vivax infections

Authors: Ernest Chan, Didier Menard, John Barnwell, Peter Zimmerman and David Serre

Citation: Malaria Journal 2014 13(Suppl 1):O41

Content type: Oral presentation Published on: 22 September 2014
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Multi-agent modeling and simulation of Plasmodium falciparum dynamics considering sulfadoxine-pyrimethamine resistance and environmental factors

Authors: Daniela Zaffalon Gomez, Andrés Olarte Dussan, Vladimir Corredor Espinel and Hernando Diaz Morales

Citation: Malaria Journal 2014 13(Suppl 1):O42

Content type: Oral presentation Published on: 22 September 2014
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Preliminary evidence from microsatellite and 2La inversion polymorphism suggests DDT resistance drives genetic differentiation between populations of Anopheles gambiae s.s. in South West Nigeria

Authors: Adedapo O Adeogun, Kehinde OK Popoola, Lizette L Koekemoer, Basil D Brooke, Adedayo O Oduola and Samson T Awolola

Citation: Malaria Journal 2014 13(Suppl 1):P1

Content type: Poster presentation Published on: 22 September 2014
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The clinical burden of microscopically patent and sub-microscopic P. falciparum and P. vivax malaria in pregnancy in Indonesia

Authors: Rukhsana Ahmed, Puji PB Asih, Rintis Noviyanti, Ismail EP Rozy, Leily Triyanti, Rita Marleta, Feiko ter Kuile and Din Syafruddin

Citation: Malaria Journal 2014 13(Suppl 1):P2

Content type: Poster presentation Published on: 22 September 2014
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Malnutrition influences tumor necrotic factor-alpha (TNF-α) response among Plasmodium falciparum (Pf) malaria patients in Nigeria

Authors: Olusola Ajibaye, Akiniyi Osuntoki, Bassey Orok, Bamidele Iwalokun, Nneka Egbuna, Yetunde Olukosi, Olugbenga Aina, Hilary Okoh, Chimere Agomo, Vera Enya, Oladayo Faneye, Samuel Akindele, Olutope Akinnibosun, Kolapo Oyebola, Sunday Adenekan and Albert Ebuehi

Citation: Malaria Journal 2014 13(Suppl 1):P3

Content type: Poster presentation Published on: 22 September 2014
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Development of novel vaccine candidates and challenge models for Plasmodium vivax

Authors: Eduardo Alves, Ahmed Salman, Chris Janse, Shahid Khan, Adrian Hill and Arturo Reyes-Sandoval

Citation: Malaria Journal 2014 13(Suppl 1):P4

Content type: Poster presentation Published on: 22 September 2014
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Consistent mapping of government malaria records across a changing territory delimitation

Authors: Ricardo Andrade-Pacheco, Martin Mubangizi, John Quinn and Neil D Lawrence

Citation: Malaria Journal 2014 13(Suppl 1):P5

Content type: Poster presentation Published on: 22 September 2014
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Development of a pediatric formulation for treatment of P. falciparum malaria: Coartem^® (artemether-lumefantrine) Dispersible

Authors: Quique Bassat, Bernhards Ogutu, Abdoulaye DJimde, Kirstin Stricker and Kamal Hamed

Citation: Malaria Journal 2014 13(Suppl 1):P7

Content type: Poster presentation Published on: 22 September 2014
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A qualitative study exploring health seeking behaviour and cultural beliefs of mothers in paediatric malaria treatment decision-making process in Ile-Ife, South-West Nigeria

Authors: Ibrahim S Bello and Satwinder Rehal

Citation: Malaria Journal 2014 13(Suppl 1):P9

Content type: Poster presentation Published on: 22 September 2014
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Reliability of Rapid Diagnostic Tests in the diagnosis of malaria amongst children in two communities in South West Nigeria

Authors: Ibrahim S Bello, Jerome B Elusiyan, Babatunde I Awokola, Akinjide O Ogundokun, Bridget Omisore, Olanrewaju Oyegbade, Samuel Anu Olowookere, Emmanuel Akintunde Abioye-Kuteyi and Joseph O Elujoba

Citation: Malaria Journal 2014 13(Suppl 1):P10

Content type: Poster presentation Published on: 22 September 2014
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Sex, power and drugs: the murky world of malaria parasite mitochondria

Authors: Giancarlo Biagini

Citation: Malaria Journal 2014 13(Suppl 1):P11

Content type: Poster presentation Published on: 22 September 2014
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Controlled human malaria infections using aseptic, purified cryopreserved Plasmodium falciparum sporozoites administered by needle and syringe

Authors: Peter Billingsley, B Kim Lee Sim, Else Bijker, Meta Roestenberg, Kirsten Lyke, Matthew Laurens, Benjamin Mordmueller, Patricia Gomez, Seif Shekalaghe, Susanne Hodgson, Adrian Hill, Elizabeth Juma, Bernhards Ogutu, Bertrand Lell, Pedro Alonso, Salim Abdullah…

Citation: Malaria Journal 2014 13(Suppl 1):P12

Content type: Poster presentation Published on: 22 September 2014
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Differential activity of novel gametocytocidal compounds: drug mode-of-action and ex vivo efficacy

Authors: Lyn-Marie Birkholtz, Didier LeRoy, Janette Reader, Mariette Botha, Dalu Mancama and Theresa L Coetzer

Citation: Malaria Journal 2014 13(Suppl 1):P13

Content type: Poster presentation Published on: 22 September 2014
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Development of an in vitro Plasmodium parasite killing assay for the evaluation of cell-mediated immune responses following vaccination with pre-erythrocytic malaria vaccine candidates

Authors: Carly M Bliss, Ahmed M Salman, Rhea J Longley, Shahid M Khan, Chris J Janse, Adrian VS Hill and Katie J Ewer

Citation: Malaria Journal 2014 13(Suppl 1):P14

Content type: Poster presentation Published on: 22 September 2014
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High frequency of submicroscopic gametocyte carriage after the treatment of uncomplicated malaria with ACTs

Authors: Marielle Karine Bouyou-Akotet, DP Mawili-Mboumba, R Nikiema Ndong, E Kendjo, Brigitte Charron, Valérie Lameyre and Maryvonne Kombila

Citation: Malaria Journal 2014 13(Suppl 1):P15

Content type: Poster presentation Published on: 22 September 2014
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Humoral immunogenicity of ChAd63_MVA ME-TRAP vaccination in African infants and children

Authors: Georgina Bowyer, Muhammed O Afolabi, Carly M Bliss, Alfred B Tiono, Abdoulie Drammeh, Issa Nébié, Ya Jankey Jagne, Jean Baptiste Yaro, Egeruan B Imoukhuede, Katie L Flanagan, Beate Kampman, Nicola Viebig, Sodiomon B Sirima, Kalifa Bojang, Adrian VS Hill and Katie J Ewer

Citation: Malaria Journal 2014 13(Suppl 1):P16

Content type: Poster presentation Published on: 22 September 2014
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An immunoproteomic approach reveals a different pattern of non-infected erythrocyte membrane protein recognition by antibodies from non-anemic and anemic patients with patent Plasmodium vivax infection

Authors: Luiza Mourao, Maira Pucci, Zelia Almeida, Rosiane Pereira, Cor Jesus Fontes, Marcus Lacerda, Marcelo Bemquerer and Erika Braga

Citation: Malaria Journal 2014 13(Suppl 1):P17

Content type: Poster presentation Published on: 22 September 2014
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Aspidosperma species (Apocynaceae) as sources of antimalarials: from the in vitro antiplasmodial activity of extracts to pre-clinical toxicological studies for the development of efficient and safe antimalarial phytomedicines

Authors: Alaide Braga de Oliveira, Renata Cristina de Paula, Maria Fani Dolabela, Fabiola Rocha, Fabiana Gomes, Giovanny Garavito, Geraldo Célio Brandão, Fúlvio Mendes and Ricardo Tabach

Citation: Malaria Journal 2014 13(Suppl 1):P18

Content type: Poster presentation Published on: 22 September 2014
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A comparison of the duration of post-treatment protection of artemether-lumefantrine, dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated malaria

Authors: Michael T Bretscher, Jamie T Griffin, Pierre Hugo, Mark Baker, Azra Ghani and Lucy Okell

Citation: Malaria Journal 2014 13(Suppl 1):P19

Content type: Poster presentation Published on: 22 September 2014
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Challenges in malaria research: Core science and innovation

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