In the widely-used mouse model of cerebral malaria (CM), infecting C57BL/6 mice with P. berghei ANKA parasites, the authors describe measurements of three proteins belonging to the complement-system in the brain and in the serum of mice with different degrees of severity of neurological symptoms and uninfected controls.
Re-emergence of malaria in the Anhui Province of China. This paper applies GIS and modern mapping techniques to analyse the spatial distribution of cases in the province.
The maps provide valuable information for selective vector control in Mali and may serve as a decision support tool for the basis for future malaria control strategies including genetically manipulated mosquitoes.
The antigens expressed at the surface of infected cells are critical virulence factors. The particular domain structure and sequence of each PfEMP1 determines its host-molecule binding phenotype. Whether binding occurs to host receptors in the brain or in other tissues is one of the factors that determine disease outcome. The data in this paper contribute to existing evidence.
The publication of the Trager and Jensen paper in 1976 has been of undoubted importance in contributing to a massive expansion in research on human malaria. This paper makes a theoretical analysis of some of the features of in vitro cultures.
