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51.

13484
Accesses

Research   Open Access Highly Accessed

The challenges of changing national malaria drug policy to artemisinin-based combinations in Kenya

Abdinasir A Amin, Dejan Zurovac, Beth B Kangwana, Joanne Greenfield, Dorothy N Otieno, Willis S Akhwale, Robert W Snow Malaria Journal 2007, 6:72 (29 May 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A narrative description of the process of anti-malarial drug policy change, financing and implementation in Kenya has been structured to capture the timing of events, the difficulties and hurdles faced and the resolutions reached to the final implementation of a new treatment policy. The article examines why it took over 32 months from announcing a drug policy change to completing early implementation.

52.

13372
Accesses

Case study   Open Access Highly Accessed

Impact of home-based management of malaria on health outcomes in Africa: a systematic review of the evidence

Heidi Hopkins, Ambrose Talisuna, Christopher JM Whitty, Sarah G Staedke Malaria Journal 2007, 6:134 (8 October 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Home-based management of malaria, which involves presumptively treating febrile children with pre-packaged antimalarial drugs distributed by members of the community, is promoted as a major strategy to improve prompt delivery of effective malaria treatment in Africa. Of 1,069 potentially relevant publications identified, only six studies were identified as meeting inclusion criteria. Heterogeneity of the evaluations, including variability in study design, precluded meta-analysis and overall results were mixed.

53.

13324
Accesses

Research   Open Access Highly Accessed

Factors associated with use and non-use of mosquito nets owned in Oromia and Amhara Regional States, Ethiopia

Carol A Baume, Richard Reithinger, Sara Woldehanna Malaria Journal 2009, 8:264 (23 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The authors present important and original in-depth information on the reasons for use and non-use of ITNs. Such information is timely and of relevance to malaria control programmes throughout the region

54.

13306
Accesses

Research   Open Access Highly Accessed

Decorticate, decerebrate and opisthotonic posturing and seizures in Kenyan children with cerebral malaria

Richard Idro, Godfrey Otieno, Steven White, Anderson Kahindi, Greg Fegan, Bernhards Ogutu, Sadik Mithwani, Kathryn Maitland, Brian GR Neville, Charles RJC Newton Malaria Journal 2005, 4:57 (7 December 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A retrospective analysis of 15,506 children admitted to Kilifi District Hospital over a three-year period, showed that 426 had cerebral malaria and that abnormal motor posturing was a common clinical feature in this group of children. The authors consider a number of potential aetiologies for the three forms of posturing observed and conclude the raised intracranial pressure and retinal signs, especially in older children, may be important.

55.

13164
Accesses

Methodology   Open Access Highly Accessed

Low sensitivity of nested PCR using Plasmodium DNA extracted from stained thick blood smears: an epidemiological retrospective study among subjects with low parasitaemia in an endemic area of the Brazilian Amazon region

Kézia KG Scopel, Cor JF Fontes, Álvaro C Nunes, Maria Horta, Érika M Braga Malaria Journal 2004, 3:8 (31 March 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The extraction of DNA from fixed and stained blood films is a useful methodology for retrospective PCR studies. Here, the method is used to look at the incidence of mixed infections in a population.

56.

13155
Accesses

Review   Open Access Highly Accessed

A review of malaria vaccine clinical projects based on the WHO rainbow table

Lauren Schwartz, Graham V Brown, Blaise Genton, Vasee S Moorthy Malaria Journal 2012, 11:11 (9 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This review succeeds in its primary objective in presenting the most comprehensive review and, of necessity, is broad and goes into much more depth than might be expected. As such it complements the WHO spreadsheet, and is a valuable companion document.

57.

13040
Accesses

Case study   Open Access Highly Accessed

A community-based health education programme for bio-environmental control of malaria through folk theatre (Kalajatha) in rural India

Susanta K Ghosh, Rajan R Patil, Satyanarayan Tiwari, Aditya P Dash Malaria Journal 2006, 5:123 (15 December 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Impact evaluation of a health education initiative, based on traditional folk theatre, explaining malaria and its control, particularly through the use of larvivorous fish used in the area

58.

13040
Accesses

Research   Open Access Highly Accessed

Severe falciparum malaria in Gabonese children: clinical and laboratory features

Arnaud Dzeing-Ella, Pascal C Nze Obiang, Rose Tchoua, Timothy Planche, Béatrice Mboza, Monique Mbounja, Ulrich Muller-Roemer, Joseph Jarvis, Eric Kendjo, Edouard Ngou-Milama, Peter G Kremsner, Sanjeev Krishna, Maryvonne Kombila Malaria Journal 2005, 4:1 (9 January 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A large scale clinical study of severe malaria in children, performed in a hospital setting in Gabon, confirms many of the features described elsewhere, showing that the highest case fatality rates were in cases with hyperlactataemia and cerebral malaria. The authors suggest that early and appropriate diagnostic, classification and treatment of malaria may help to reduce the mortality.

59.

13016
Accesses

Research   Open Access Highly Accessed

Gains in awareness, ownership and use of insecticide-treated nets in Nigeria, Senegal, Uganda and Zambia

Carol A Baume, M Celeste Marin Malaria Journal 2008, 7:153 (7 August 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A mix of increased demand, strengthened commercial sector, reduced taxes and tariffs, and programmes making ITNs available at reduced prices resulted in impressive gains in awareness, ownership, and use of nets. None of the four countries reached the ambitious Abuja targets, but they made substantial progress towards them.

60.

13005
Accesses

Commentary   Open Access Highly Accessed

An online operational rainfall-monitoring resource for epidemic malaria early warning systems in Africa

Emily Grover-Kopec, Mika Kawano, Robert W Klaver, Benno Blumenthal, Pietro Ceccato, Stephen J Connor Malaria Journal 2005, 4:6 (21 January 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Rainfall is one of the major factors triggering epidemics in warm semi-arid and desert-fringe areas. Consequently, rainfall monitoring forms one of the essential elements for the development of integrated Malaria Early Warning Systems for sub-Saharan Africa. The paper presents a new monitoring interface that enables the user to interpret rainfall data. These resources are available at no cost to the user and are updated on a routine basis.

61.

12977
Accesses

Review   Open Access Highly Accessed

World Antimalarial Resistance Network (WARN) III: Molecular markers for drug resistant malaria

Christopher V Plowe, Cally Roper, John W Barnwell, Christian T Happi, Hema H Joshi, Wilfred Mbacham, Steven R Meshnick, Kefas Mugittu, Inbarani Naidoo, Ric N Price, Robert W Shafer, Carol H Sibley, Colin J Sutherland, Peter A Zimmerman, Philip J Rosenthal Malaria Journal 2007, 6:121 (6 September 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The review describes previous successes on using molecular markers of drug resistance and lessons learned. A standardized global database of molecular markers of drug resistance linking up with databases containing in vivo efficacy trial results, in vitro and pharmacokinetic studies could form an essential resource to guide policy makers in choice of first line antimalarial drugs, drugs for intermittent preventive treatment (IPT) and prophylactic drugs for travellers.

62.

12952
Accesses

Research   Open Access Highly Accessed

A steep decline of malaria morbidity and mortality trends in Eritrea between 2000 and 2004: the effect of combination of control methods

Peter M Nyarango, Tewolde Gebremeskel, Goitom Mebrahtu, Jacob Mufunda, Usman Abdulmumini, Andom Ogbamariam, Andrew Kosia, Andemariam Gebremichael, Disanayike Gunawardena, Yohannes Ghebrat, Yahannes Okbaldet Malaria Journal 2006, 5:33 (24 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The National Malaria Control Programme in Eritrea is rightly considered to be one of the major success stories to come out of the recent efforts to scale up malaria control using a combination of control methods. The programme has, over a short period, dramatically increased control measures in most of the endemic and epidemic areas in the country.

63.

12915
Accesses

Research   Open Access Highly Accessed

Impact of national malaria control scale-up programmes in Africa: magnitude and attribution of effects

Richard W Steketee, Carlos C Campbell Malaria Journal 2010, 9:299 (27 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

After over 5 years of intense intervention scale-up, the present paper puts together some data from a number of sub-Saharan countries to document impact on morbidity and mortality.

64.

12894
Accesses

Research   Open Access Highly Accessed

The epidemiology of malaria in adults in a rural area of southern Mozambique

Alfredo Mayor, John J Aponte, Carole Fogg, Francisco Saúte, Brian Greenwood, Martinho Dgedge, Clara Menendez, Pedro L Alonso Malaria Journal 2007, 6:3 (17 January 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The role of adults and semi-immunity in the epidemiology of malaria is still imperfectly know. This study looks at a cohort of adults having reached a stage of non-sterile, protective immunity, but still presenting occasional symptoms, including diarrhoea and headaques

65.

12885
Accesses

Methodology   Open Access Highly Accessed

A new ELISA kit which uses a combination of Plasmodium falciparum extract and recombinant Plasmodium vivax antigens as an alternative to IFAT for detection of malaria antibodies

Cecile Doderer, Aurelie Heschung, Phillippe Guntz, Jean-Pierre Cazenave, Yves Hansmann, Alexandre Senegas, Alexander W Pfaff, Tamer Abdelrahman, Ermanno Candolfi Malaria Journal 2007, 6:19 (21 February 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Serology does not have a place in the diagnosis of clinical malaria, but it is the best option for the eliminating contaminated units of blood in a blood banking context. While ELISA is one of the most promising serological tests for the purpose and this study provides the first reasonable evidence that ELISA replacement of IFAT for malaria serodiagnosis may be advantageous.

66.

12692
Accesses

Review   Open Access Highly Accessed

A database of antimalarial drug resistance

Carol Sibley, Pascal Ringwald Malaria Journal 2006, 5:48 (15 June 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Currently, there is no publically-accessible, central database that contains information on the levels of resistance to antimalaria drugs in different countries. The authors of this review outline the potential role of such a database for an informed utlization of drugs and they describe what would be required to create it.

67.

12546
Accesses

Research   Open Access Highly Accessed

Use of antenatal care, maternity services, intermittent presumptive treatment and insecticide treated bed nets by pregnant women in Luwero district, Uganda

Mpungu S Kiwuwa, Patrobas Mufubenga Malaria Journal 2008, 7:44 (1 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This paper nicely describes through a community-based study the uptake of ANC services and malaria control measures in pregnant women of one district in Uganda.

68.

12501
Accesses

Research   Open Access Highly Accessed

Successful field trial of attractive toxic sugar bait (ATSB) plant-spraying methods against malaria vectors in the Anopheles gambiae complex in Mali, West Africa

Günter C Müller, John C Beier, Sekou F Traore, Mahamoudou B Toure, Mohamed M Traore, Sekou Bah, Seydou Doumbia, Yosef Schlein Malaria Journal 2010, 9:210 (21 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This study in Mali shows that even a single application of ATSB can substantially decrease malaria vector population densities and longevity. It is likely that ATSB methods can be used as a new powerful tool for the control of malaria vectors, particularly since this approach is highly effective for mosquito control, technologically simple, inexpensive, and environmentally safe.

69.

12434
Accesses

Research   Open Access Highly Accessed

The heat shock protein 90 of Plasmodium falciparum and antimalarial activity of its inhibitor, geldanamycin

Rajinder Kumar, Alla Musiyenko, Sailen Barik Malaria Journal 2003, 2:30 (15 September 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Hsp90 appears to be expressed at all stages of development in malaria parasites and the paper shows that the anticancer drug geldanamycin is equally effective against all stages of chloroquine-resistant and chloroquine-sensitive parasites, and that the two agents act synergistically.

70.

12390
Accesses

Research   Open Access Highly Accessed

Placental malaria and low birth weight in pregnant women living in a rural area of Burkina Faso following the use of three preventive treatment regimens

Alfred B Tiono, Alphonse Ouedraogo, Edith C Bougouma, Amidou Diarra, Amadou T Konaté, Issa Nébié, Sodiomon B Sirima Malaria Journal 2009, 8:224 (7 October 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Intermittent preventive treatment with SP has shown clear superiority in reducing adverse outcomes at delivery, as compared with intermittent preventive treatment with CQ and classical chemoprophylaxis with CQ.

71.

12233
Accesses

Research   Open Access Highly Accessed

A simulation model of African Anopheles ecology and population dynamics for the analysis of malaria transmission

Jean-Marc O Depinay, Charles M Mbogo, Gerry Killeen, Bart Knols, John Beier, John Carlson, Jonathan Dushoff, Peter Billingsley, Henry Mwambi, John Githure, Abdoulaye M Toure, F Ellis McKenzie Malaria Journal 2004, 3:29 (30 July 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A process-driven model of malaria transmission which allows a better understanding of the mechanisms underlying Anopheles population dynamics.

72.

12222
Accesses

Opinion   Open Access Highly Accessed

Mosquitoes and transmission of malaria parasites – not just vectors

Richard EL Paul, Mawlouth Diallo, Paul T Brey Malaria Journal 2004, 3:39 (8 November 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Using historical datasets, from three different studies, the paper formulates hypotheses regarding transmission dynamics, suggesting that it is the mosquito bite itself which controls the onset of gametocytogenesis in the vertebrate host and, thus, kick-starts transmission at the beginning of the rainy season.

73.

12106
Accesses

Commentary   Open Access Highly Accessed

Improving epidemic malaria planning, preparedness and response in Southern Africa

Joaquim DaSilva, Brad Garanganga, Vonai Teveredzi, Sabine M Marx, Simon J Mason, Stephen J Connor Malaria Journal 2004, 3:37 (22 October 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Report on the first Southern Africa Regional Epidemiology Outlook Forum, held in Harare, Zimbabwe, September 2004. The report comments on major issues discussed at the meeting and the final recommendations.

74.

12049
Accesses

Research   Open Access Highly Accessed

The unexpected importance of mosquito oviposition behaviour for malaria: non-productive larval habitats can be sources for malaria transmission

Arnaud Menach, F Ellis McKenzie, Antoine Flahault, David L Smith Malaria Journal 2005, 4:23 (13 May 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A mathematical model exploring the egg laying behaviour of mosquito females and its implications on malaria epidemiology in various scenarios.

75.

12025
Accesses

Methodology   Open Access Highly Accessed

Detection of knockdown resistance (kdr) mutations in Anopheles gambiae: a comparison of two new high-throughput assays with existing methods

Chris Bass, Dimitra Nikou, Martin J Donnelly, Martin S Williamson, Hilary Ranson, Amanda Ball, John Vontas, Linda M Field Malaria Journal 2007, 6:111 (13 August 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The presence of kdr mutations has been monitored using a variety of molecular techniques. In this study, two new high-throughput assays were developed and compared with four established techniques

76.

11999
Accesses

Research   Open Access Highly Accessed

Plasmodium vivax trophozoites insensitive to chloroquine

Wesley W Sharrock, Rossarin Suwanarusk, Usa Lek-Uthai, Michael D Edstein, Varakorn Kosaisavee, Thomas Travers, Anchalee Jaidee, Kanlaya Sriprawat, Ric N Price, François Nosten, Bruce Russell Malaria Journal 2008, 7:94 (27 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A study that provides important data about the action of chloroquine in Plasmodium vivax and highlights the fundamental differences with Plasmodium falciparum.

77.

11975
Accesses

Research   Open Access Highly Accessed

Landscape determinants and remote sensing of anopheline mosquito larval habitats in the western Kenya highlands

Emmanuel Mushinzimana, Stephen Munga, Noboru Minakawa, Li Li, Chen-chieh Feng, Ling Bian, Uriel Kitron, Cindy Schmidt, Louisa Beck, Guofa Zhou, Andrew K Githeko, Guiyun Yan Malaria Journal 2006, 5:13 (16 February 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A study which examines the landscape determinants of anopheline mosquito larval habitats and usefulness of remote sensing in identifying these habitats in western Kenya highlands, an area which has experienced several major malaria epidemics during the past two decades.

78.

11954
Accesses

Research   Open Access Highly Accessed

Evaluation of Olyset™ insecticide-treated nets distributed seven years previously in Tanzania

Adriana Tami, Godfrey Mubyazi, Alison Talbert, Hassan Mshinda, Stéphane Duchon, Christian Lengeler Malaria Journal 2004, 3:19 (29 June 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Olyset nets and PermaNets are the only two long-lasting insecticidal nets currently available. This retrospective study shows that Olyset nets are popular, durable and with a much longer insecticide persistence than ordinary polyester nets. ITN programmes in rural malaria-endemic areas have shown that the re-treatment of nets faces numerous logistic problems and that a switch to long-lasting insecticidal nets represents, therefore, a very attractive option.

79.

11941
Accesses

Research   Open Access Highly Accessed

Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand

Dinora Lopes, Kanchana Rungsihirunrat, Fátima Nogueira, Aree Seugorn, José Gil, Virgilio E do Rosário, Pedro Cravo Malaria Journal 2002, 1:12 (14 October 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

This should appear in MY BMC if you have Infectious Diseases as your subject. It has a man_interest of 2

80.

11887
Accesses

Research   Open Access Highly Accessed

A randomized trial of artemether-lumefantrine versus mefloquine-artesunate for the treatment of uncomplicated multi-drug resistant Plasmodium falciparum on the western border of Thailand

Robert Hutagalung, Lucy Paiphun, Elizabeth A Ashley, Rose McGready, Alan Brockman, Kaw L Thwai, Pratap Singhasivanon, Thomas Jelinek, Nicholas J White, François H Nosten Malaria Journal 2005, 4:46 (22 September 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A comparative study of the efficacy and tolerability of two artemisinin combination therapies which are very useful for treatment of P. falciparum malaria multidrug-resistant in Asia. These two ACTs are, currently, the best treatment for non-severe falciparum malaria and this trial provides base-line data for future longitudinal surveillance of efficacy.

81.

11846
Accesses

Research   Open Access Highly Accessed

Paracheck-Pf® accuracy and recently treated Plasmodium falciparum infections: is there a risk of over-diagnosis?

Todd D Swarthout, Helen Counihan, Raphael Senga, Ingrid van den Broek Malaria Journal 2007, 6:58 (16 May 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Though the RDT is as sensitive as microscopy in detecting true malaria cases, low specificity resulted in a high frequency of false-positive results. This was aggravated by a duration of RDT false-positivity after effective treatment that was significantly longer than reported by the manufacturer. Presence of false positive results show the need to avoid clinicians inappropriately focusing on malaria, not identifying the true cause of illness and providing unnecessary treatment.

82.

11837
Accesses

Research   Open Access Highly Accessed

Anti-malarial activities of Andrographis paniculata and Hedyotis corymbosa extracts and their combination with curcumin

Kirti Mishra, Aditya P Dash, Bijay K Swain, Nrisingha Dey Malaria Journal 2009, 8:26 (12 February 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The study investigates the possible anti-malarial activity of extracts from two ancient medicinal plants, which are used in Asia to treat fever. Both extracts show promising activity, especially when combined.

83.

11812
Accesses

Research   Open Access Highly Accessed

Ethnobotanical study of some of mosquito repellent plants in north-eastern Tanzania

Eliningaya J Kweka, Franklin Mosha, Asanterabi Lowassa, Aneth M Mahande, Jovin Kitau, Johnson Matowo, Michael J Mahande, Charles P Massenga, Filemoni Tenu, Emmanuel Feston, Ester E Lyatuu, Michael A Mboya, Rajabu Mndeme, Grace Chuwa, Emmanuel A Temu Malaria Journal 2008, 7:152 (7 August 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The use of plant repellents against nuisance biting insects is common and has a potential role as a complementary measure for malaria vector control. The essential oils of Ocimum suave and Ocimum kilimandscharicum were evaluated in this paper.

84.

11699
Accesses

Review   Open Access Highly Accessed

Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space?

Lyn-Marie Birkholtz, Olivier Bastien, Gordon Wells, Delphine Grando, Fourie Joubert, Vinod Kasam, Marc Zimmermann, Philippe Ortet, Nicolas Jacq, Nadia Saïdani, Sylvaine Roy, Martin Hofmann-Apitius, Vincent Breton, Abraham I Louw, Eric Maréchal Malaria Journal 2006, 5:110 (17 November 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A review of the different tools and strategies that have recently been developed to process the huge amount of data produced by the X-omic projects. This includes the comparison of protein sequences, high throughput reconstruction of molecular phylogenies, representation of biological processes, methods to integrate X-omic generated data following drug treatments and in silico prediction of protein structure and identification of specific ligand.

85.

11686
Accesses

Research   Open Access Highly Accessed

Characterisation and expression of a PP1 serine/threonine protein phosphatase (PfPP1) from the malaria parasite, Plasmodium falciparum: demonstration of its essential role using RNA interference

Rajinder Kumar, Brian Adams, Anja Oldenburg, Alla Musiyenko, Sailen Barik Malaria Journal 2002, 1:5 (26 April 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

86.

11677
Accesses

Research   Open Access Highly Accessed

A theoretical approach to predicting the success of genetic manipulation of malaria mosquitoes in malaria control

Christophe Boëte, Jacob C Koella Malaria Journal 2002, 1:3 (25 February 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

87.

11668
Accesses

Research   Open Access

Cellular immune response to Plasmodium falciparum after pregnancy is related to previous placental infection and parity

Nadine Fievet, Germaine Tami, Bertrand Maubert, Marlène Moussa, Ian K Shaw, Michel Cot, Anthony A Holder, Gérard Chaouat, Philippe Deloron Malaria Journal 2002, 1:16 (26 November 2002)

Abstract | Full text | PDF | PubMed

88.

11664
Accesses

Commentary   Open Access Highly Accessed

Malaria prophylaxis policy for travellers from Europe to the Indian Sub Continent

RH Behrens, Z Bisoffi, A Björkman, J Gascon, C Hatz, T Jelinek, F Legros, N Mühlberger, TropNetEurop, P Voltersvik Malaria Journal 2006, 5:7 (1 February 2006)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A group of specialists in travel medicine, representative of various European institutions, propose that the policy of non-selective prescribing of chemoprophylaxis for visitors to India, Pakistan, Bangladesh and Sri Lanka should be dropped. The group consensus was that the likelihood of severe adverse events of regularly used prophylactic agents are significantly higher than the risk of acquiring malaria in these four countries.

89.

11612
Accesses

Methodology   Open Access Highly Accessed

Isolation of Plasmodium berghei ookinetes in culture using Nycodenz density gradient columns and magnetic isolation

Victoria Carter, Hazel C Cable, B Ann Underhill, Jackie Williams, Hilary Hurd Malaria Journal 2003, 2:35 (3 November 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A methodology paper comparing two techniques for isolating malaria ookinetes from culture.

90.

11529
Accesses

Research   Open Access Highly Accessed

Malaria resurgence: a systematic review and assessment of its causes

Justin M Cohen, David L Smith, Chris Cotter, Abigail Ward, Gavin Yamey, Oliver J Sabot, Bruno Moonen Malaria Journal 2012, 11:122 (24 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

There is a need for practical solutions to the operational and financial threats facing malaria elimination programmes if we are to avoid repeating the mistakes of the past, which saw the resurgence of malaria in disease free areas.

91.

11450
Accesses

Research   Open Access Highly Accessed

Larvicidal activity of neem oil (Azadirachta indica) formulation against mosquitoes

Virendra K Dua, Akhilesh C Pandey, Kamaraju Raghavendra, Ashish Gupta, Trilochan Sharma, Aditya P Dash Malaria Journal 2009, 8:124 (8 June 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Description of the effect of a neem oil formulation, shown to be effective in controlling mosquito larvae in different breeding sites under natural field conditions. Claimed to be an eco-friendly larvicide, which could be used as an additional tool for malaria control.

92.

11403
Accesses

Research   Open Access Highly Accessed

Endemic malaria: an 'indoor' disease in northern Europe. Historical data analysed

Lena Huldén, Larry Huldén, Kari Heliövaara Malaria Journal 2005, 4:19 (25 April 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Cold climate malaria is no longer a major problem today, but it produced devastating epidemics in the past. This historical account, based on good quality records from Finland, makes an important contribution to our knowledge. It also makes one paradoxical observation, that transmission was more likely to have been indoors in winter than outdoors in summer.

93.

11282
Accesses

Research   Open Access Highly Accessed

Initial evidence of reduction of malaria cases and deaths in Rwanda and Ethiopia due to rapid scale-up of malaria prevention and treatment

Mac Otten, Maru Aregawi, Wilson Were, Corine Karema, Ambachew Medin, Worku Bekele, Daddi Jima, Khoti Gausi, Ryuichi Komatsu, Eline Korenromp, Daniel Low-Beer, Mark Grabowsky Malaria Journal 2009, 8:14 (14 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Initial evidence indicates that the combination of mass distribution of LLIN to all children below five years and nationwide distribution of ACT in the public sector was associated with substantial declines of in-patient malaria cases and deaths in Rwanda and Ethiopia. Clinic-based data was a useful tool for local monitoring of the impact of malaria programmes.

94.

11282
Accesses

Research   Open Access Highly Accessed

Large-scale malaria survey in Cambodia: Novel insights on species distribution and risk factors

Sandra Incardona, Sirenda Vong, Lim Chiv, Pharath Lim, Sina Nhem, Rithy Sem, Nimol Khim, Socheat Doung, Odile Mercereau-Puijalon, Thierry Fandeur Malaria Journal 2007, 6:37 (27 March 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A good insight into the malaria situation in Cambodia, in particular the patchy situation at the district and even the village level. The malaria risk factors identified for both falciparum and vivax malaria lead to recommendations for improving malaria control throughout South-East Asia.

95.

11238
Accesses

Research   Open Access Highly Accessed

Inequalities in purchase of mosquito nets and willingness to pay for insecticide-treated nets in Nigeria: Challenges for malaria control interventions

Obinna Onwujekwe, Kara Hanson, Julia Fox-Rushby Malaria Journal 2004, 3:6 (16 March 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A socio-economic study of the potential inequity that may result from ITN distribution and marketing strategies based on user charges.

96.

11198
Accesses

Research   Open Access

Sex-specific and blood meal-induced proteins of Anopheles gambiae midguts: analysis by two-dimensional gel electrophoresis

GI Prévot, C Laurent-Winter, F Rodhain, C Bourgouin Malaria Journal 2003, 2:1 (11 February 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

97.

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Methodology   Open Access Highly Accessed

Improved isolation of murine hepatocytes for in vitro malaria liver stage studies

Lígia A Gonçalves, Ana M Vigário, Carlos Penha-Gonçalves Malaria Journal 2007, 6:169 (20 December 2007)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Primary hepatocyte cultures are a valuable tool for the understanding of cellular and molecular phenomena occurring during malaria liver stage. This paper describes an improved procedure for the isolation of hepatocytes which allows a reproducible preparation of primary hepatocytes with consistent cell yields and controlled purity.

98.

11165
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Methodology   Open Access Highly Accessed

Computer vision for microscopy diagnosis of malaria

F Boray Tek, Andrew G Dempster, Izzet Kale Malaria Journal 2009, 8:153 (13 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Improving malaria diagnostics by computer-assisted microscopy is close to becoming reality: this paper emphasizes the hopes and problems that are encountered with pattern recognition analysis of blood films.

99.

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Commentary   Open Access Highly Accessed

Battling the malaria iceberg with chloroquine in India

Vinod P Sharma Malaria Journal 2007, 6:105 (7 August 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The continuation of an outdated drug in the treatment of P. falciparum is counterproductive in fighting drug-resistant malaria. A switchover to ACT in the treatment of all P. falciparum cases, a ban on artemisinin monotherapy and an effective vector control (treated nets/efficient insecticide spraying) would be a rational approach to malaria control in India.

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Case report   Open Access Highly Accessed

Congenital malaria with atypical presentation: A case report from low transmission area in India

Neena Valecha, Sunita Bhatia, Sadhna Mehta, Sukla Biswas, Aditya P Dash Malaria Journal 2007, 6:43 (13 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The case emphasizes the importance of considering the diagnosis of malaria even in infants in low transmission area, who may not present with typical symptoms of malaria

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