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	1. 2822 Accesses	Commentary It is time to rethink tactics in the fight against malaria Laurence Slutsker, S Kachur Malaria Journal 2013, 12:140 (24 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary On world malaria day, renowned malariologists from CDC discuss dangers and resilience, despite successful control in many areas, and how we may need to rethink our strategy in order to defeat the parasite.
	2. 1980 Accesses	Research Urbanization and the global malaria recession Andrew J Tatem, Peter W Gething, David L Smith, Simon I Hay Malaria Journal 2013, 12:133 (17 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Article that adds significant quantitative information to our understanding of the association of malaria and urbanization worldwide.
	3. 1656 Accesses	Review Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria Jane Achan, Ambrose O Talisuna, Annette Erhart, Adoke Yeka, James K Tibenderana, Frederick N Baliraine, Philip J Rosenthal, Umberto D'Alessandro Malaria Journal 2011, 10:144 (24 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary This review of quinine is useful, because the drug still plays an important role in the treatment of malaria.
	4. 1538 Accesses	Review Review of key knowledge gaps in glucose-6-phosphate dehydrogenase deficiency detection with regard to the safe clinical deployment of 8-aminoquinoline treatment regimens: a workshop report Lorenz von Seidlein, Sarah Auburn, Fe Espino, Dennis Shanks, Qin Cheng, James McCarthy, Kevin Baird, Catherine Moyes, Rosalind Howes, Didier Ménard, Germana Bancone, Ari Winasti-Satyahraha, Lasse S Vestergaard, Justin Green, Gonzalo Domingo, Shunmay Yeung, Ric Price Malaria Journal 2013, 12:112 (27 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A review based on the conclusions of an important meeting looking at the knowledge gaps in G6PD deficiency with regards to the safe implementation of 8 - aminoquinolines.
	5. 1531 Accesses	Research Impact of malaria during pregnancy on pregnancy outcomes in a Ugandan prospective cohort with intensive malaria screening and prompt treatment Pierre De Beaudrap, Eleanor Turyakira, Lisa J White, Carolyn Nabasumba, Benon Tumwebaze, Atis Muehlenbachs, Philippe J Guérin, Yap Boum, Rose McGready, Patrice Piola Malaria Journal 2013, 12:139 (24 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Malaria in pregnancy is a major public health problem in endemic areas of sub-Saharan Africa and has important consequences on birth outcome. In this study, the timing, parasitaemia level and number of peripherally-detected malaria infections, but not the presence of fever, were associated with adverse birth outcomes. Hence, prompt malaria detection and treatment should be offered to pregnant women, with increased focus on mothers living in remote areas.
	6. 1505 Accesses	Case study Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination Carlos J Chaccour, Kevin C Kobylinski, Quique Bassat, Teun Bousema, Chris Drakeley, Pedro Alonso, Brian D Foy Malaria Journal 2013, 12:153 (7 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A topic of high importance to the vector control community and reflects recent discussions on the current challenges in malaria prevention and control ¿ specifically, development of new tools for niche transmission settings (i.e., outdoors) where current interventions, such as ITNs and IRS may not be effective.
	7. 1305 Accesses	Research Early parasitological response following artemisinin-containing regimens: a critical review of the literature Debashish Das, Ric N Price, Delia Bethell, Philippe J Guerin, Kasia Stepniewska Malaria Journal 2013, 12:125 (19 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A literature review of prospective clinical trials of artemisinin combination therapy trials with the aim of determining the incidence persistent parasitaemia after treatment. Although crude, the proportion of patients remaining parasitaemic on D3 has been proposed as a marker possibly signalling the presence of resistance to the artemisinin component of ACT therapy. This is the first published large review of its kind.
	8. 1177 Accesses	Review A review of malaria vaccine clinical projects based on the WHO rainbow table Lauren Schwartz, Graham V Brown, Blaise Genton, Vasee S Moorthy Malaria Journal 2012, 11:11 (9 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary This review succeeds in its primary objective in presenting the most comprehensive review and, of necessity, is broad and goes into much more depth than might be expected. As such it complements the WHO spreadsheet, and is a valuable companion document.
	9. 1172 Accesses	Research Development of a population suppression strain of the human malaria vector mosquito, Anopheles stephensi Osvaldo Marinotti, Nijole Jasinskiene, Aniko Fazekas, Sarah Scaife, Guoliang Fu, Stefanie T Mattingly, Karissa Chow, David M Brown, Luke Alphey, Anthony A James Malaria Journal 2013, 12:142 (26 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary The study uses a female-specific gene promoter back engineered from Aedes aegypti for the Indian urban malaria vector Anopheles stephensi. The technology uses an antibiotic-repressible lethal factor to produce a sex-specific flightless transgene phenotype.
	10. 1128 Accesses	Research Clinical performance of an automated reader in interpreting malaria rapid diagnostic tests in Tanzania Seif Shekalaghe, Marcela Cancino, Caroline Mavere, Omar Juma, Ali Mohammed, Salim Abdulla, Santiago Ferro Malaria Journal 2013, 12:141 (24 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Paper reporting the performance of an automated malaria RDT reader with a network 'cloud' connectivity. The Deki reader is as good as an experienced visual read and can add to the issue of misinterpretation of RDT results by providing a novel mechanism for quality assurance.
	11. 1124 Accesses	Research Over-diagnosis of malaria by microscopy in the Kilombero Valley, Southern Tanzania: an evaluation of the utility and cost-effectiveness of rapid diagnostic tests Kelly Harchut, Claire Standley, Andrew Dobson, Belia Klaassen, Clotilde Rambaud-Althaus, Fabrice Althaus, Katarzyna Nowak Malaria Journal 2013, 12:159 (10 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Presumptive treatment used to be recommended by WHO, on the assumption that it is safer to treat non-malarial patients with anti-malarials than missing a true case of malaria. With a reduced incidence of malaria, a much increased cost of treatment and the realization of the risks of not identifying the true cause of febrile illness, there is now greater emphasis on accurate biological diagnosis. This study shows the advantages of using RDTs compared to poor quality microscopy.
	12. 1005 Accesses	Research A new world malaria map: Plasmodium falciparum endemicity in 2010 Peter W Gething, Anand P Patil, David L Smith, Carlos A Guerra, Iqbal RF Elyazar, Geoffrey L Johnston, Andrew J Tatem, Simon I Hay Malaria Journal 2011, 10:378 (20 December 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The paper represents a Herculean effort to provide an updated map of the global distribution of malaria, based on three key malariometric indices PfPR, PfEIR and PfRC and represents a unique contribution.
	13. 1001 Accesses	Research Malaria resurgence: a systematic review and assessment of its causes Justin M Cohen, David L Smith, Chris Cotter, Abigail Ward, Gavin Yamey, Oliver J Sabot, Bruno Moonen Malaria Journal 2012, 11:122 (24 April 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary There is a need for practical solutions to the operational and financial threats facing malaria elimination programmes if we are to avoid repeating the mistakes of the past, which saw the resurgence of malaria in disease free areas.
	14. 946 Accesses	Research Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission Bernadette J Huho, Gerard F Killeen, Heather M Ferguson, Adriana Tami, Christian Lengeler, J Derek Charlwood, Aniset Kihonda, Japhet Kihonda, S Patrick Kachur, Thomas A Smith, Salim MK Abdulla Malaria Journal 2012, 11:118 (18 April 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A study of the impact of artesunate/SP use on oocyst/sporozoite carriage in mosquitoes. It is not unexpected that in an area of intense malaria transmission, with presumed large numbers of asymptomatic gametocyte carriers, that ACT does not result in a marked reduction in transmission indices. Whilst the result in not unexpected the methodology is thorough and is likely to be useful to others.
	15. 928 Accesses	Reviewer acknowledgement Reviewer acknowledgement Marcel Hommel Malaria Journal 2013, 12:83 (17 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	16. 896 Accesses	Research High level of resistance in the mosquito Anopheles gambiae to pyrethroid insecticides and reduced susceptibility to bendiocarb in north-western Tanzania Natacha Protopopoff, Johnson Matowo, Robert Malima, Reginald Kavishe, Robert Kaaya, Alexandra Wright, Philippa A West, Immo Kleinschmidt, William Kisinza, Franklin W Mosha, Mark Rowland Malaria Journal 2013, 12:149 (2 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A report of bioassay data and kdr frequencies for An gambiae, which clearly demonstrate the presence of pyrethroid resistance.
	17. 884 Accesses	Research Five years of malaria control in the continental region, Equatorial Guinea Andrea M Rehman, Andrea G Mann, Christopher Schwabe, Michael R Reddy, Irina Roncon Gomes, Michel A Slotman, Lee Yellott, Abrahan Matias, Adalgisa Caccone, Gloria Nseng Nchama, Immo Kleinschmidt Malaria Journal 2013, 12:154 (7 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary The findings that both LLINs and IRS offer individual protection, after adjusting for indicators of socio-economic status, are consistent with the literature. This study corroborates previous findings that the combination of the LLINs and IRS offers greater protection than either intervention alone.
	18. 878 Accesses	Methodology The parasite clearance curve NJ White Malaria Journal 2011, 10:278 (22 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The author presents a clear and concise introduction to the parasite clearance curve, which is important in determining the therapeutic response to anti-malarials, particularly artemisinin derivatives. Given the recent reports of emerging artemisinin resistance in Western Cambodia, this is a very timely report.
	19. 842 Accesses	Research Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine Margaret E McCoy, Hannah E Golden, Tais APF Doll, Yongkun Yang, Stephen A Kaba, Peter Burkhard, David E Lanar Malaria Journal 2013, 12:136 (22 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary An important paper describing aspects of the mechanism of action for a traditional malaria vaccine (CSP) delivered in the context of a novel and exciting platform (self-assembling protein nanoparticle).
	20. 838 Accesses	Research Community perceptions on the secondary health benefits established by malaria vaccine trials (RTS,S phase 2 and phase 3) at the Korogwe site in North Eastern Tanzania Edwin A Liheluka, John P Lusingu, Rachel N Manongi Malaria Journal 2013, 12:157 (8 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary This study explored the community perceptions on the secondary health benefits of a malaria vaccine trial at the Korogwe site in Tanzania.
	21. 832 Accesses	Opinion Made in Europe: will artemisinin resistance emerge in French Guiana? Mathieu Nacher, Philippe J Guérin, Magalie Demar-Pierre, Félix Djossou, François Nosten, Bernard Carme Malaria Journal 2013, 12:152 (4 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary In their opinion piece, the authors outline the current malaria control strategy in French Guiana and the challenges associated with treating and controlling malaria in a setting that is constrained by European regulations and the inaccessibility of a large proportion of the population affected by malaria in the region.
	22. 830 Accesses	Reviews Plant-based insect repellents: a review of their efficacy, development and testing Marta Maia, Sarah J Moore Malaria Journal 2011, 10(Suppl 1):S11 (15 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 820 Accesses	Research Community-directed educational intervention for malaria elimination in Bhutan: quasi-experimental study in malaria endemic areas of Sarpang district Tashi Tobgay, Deki Pem, Ugyen Dophu, Shyam P Dumre, Kesara Na-Bangchang, Cristina E Torres Malaria Journal 2013, 12:132 (17 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary The findings from this study corroborate that community-directed interventions can be utilized as an effective means for improving knowledge, attitude and practice in the malaria-endemic areas of Bhutan.
	24. 821 Accesses	Research Physical condition of Olyset(R) nets after five years of utilization in rural western Kenya Paola Mejia, Hailay Teklehaimanot, Yihenew Tesfaye, Awash Teklehaimanot Malaria Journal 2013, 12:158 (10 May 2013) Abstract \| Provisional PDF \| PubMed
	25. 803 Accesses	Research Treatment of fevers prior to introducing rapid diagnostic tests for malaria in registered drug shops in Uganda Anthony K Mbonye, Sham Lal, Bonnie Cundill, Kristian Schultz Hansen, Siân Clarke, Pascal Magnussen Malaria Journal 2013, 12:131 (16 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary In this setting, the proportion of malaria patients receiving appropriate ACT treatment at drug shops was low. This was due to the practice of presumptive treatment, inadequate training on malaria management and lack of knowledge that ACT was the recommended first-line treatment for malaria.