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	1. 1717 Accesses	Review Malaria in South America: a drug discovery perspective Luiza R Cruz, Thomas Spangenberg, Marcus VG Lacerda, Timothy NC Wells Malaria Journal 2013, 12:168 (24 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A summary of current malaria research from the viewpoint of focusing on work affecting South America and carried out by workers in South American countries. This calls to attention the many contributions from that continent and the section presenting natural products work is the most complete in the literature.
	2. 1447 Accesses	Review Designing the next generation of medicines for malaria control and eradication Jeremy N Burrows, Rob Hooft van Huijsduijnen, Jörg J Möhrle, Claude Oeuvray, Timothy NC Wells Malaria Journal 2013, 12:187 (6 June 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary This paper provides an outline definition of the ideal and minimally acceptable characteristics of the types of clinical candidate molecule which are needed in various situations, both as monotherapy and combination therapy.
	3. 1266 Accesses	Research Community knowledge and perceptions about indoor residual spraying for malaria prevention in Soroti district, Uganda: a cross-sectional study Michael Ediau, Juliet N Babirye, Nazarius M Tumwesigye, Joseph KB Matovu, Simba Machingaidze, Olico Okui, Rhoda K Wanyenze, Peter Waiswa Malaria Journal 2013, 12:170 (27 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Knowledge about IRS is inadequate and negative perceptions about its use are prominent especially among the rural and less educated individuals. To ensure householders¿ cooperation and participation in the IRS programme, adequate community mobilization and sensitization is needed prior to use of IRS for effective malaria control.
	4. 1265 Accesses	Review Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria Jane Achan, Ambrose O Talisuna, Annette Erhart, Adoke Yeka, James K Tibenderana, Frederick N Baliraine, Philip J Rosenthal, Umberto D'Alessandro Malaria Journal 2011, 10:144 (24 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary This review of quinine is useful, because the drug still plays an important role in the treatment of malaria.
	5. 1067 Accesses	Commentary It is time to rethink tactics in the fight against malaria Laurence Slutsker, S Kachur Malaria Journal 2013, 12:140 (24 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary On world malaria day, renowned malariologists from CDC discuss dangers and resilience, despite successful control in many areas, and how we may need to rethink our strategy in order to defeat the parasite.
	6. 1038 Accesses	Research Routine parallel diagnosis of malaria using microscopy and the malaria rapid diagnostic test SD 05FK60: the experience of Médecins Sans Frontières in Myanmar Cara S Kosack, Wint Naing, Erwan Piriou, Leslie Shanks Malaria Journal 2013, 12:167 (21 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary In field conditions in Myanmar, the malaria RDT described performed consistent with other reports. The test detected malaria caused by P. vivax/P. malariae to a lesser extent than P. falciparum infection.
	7. 1034 Accesses	Research Characterizing PvARP, a novel Plasmodium vivax antigen Darwin A Moreno-Pérez, Ambar Saldarriaga, Manuel A Patarroyo Malaria Journal 2013, 12:165 (20 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Characterization of the P. vivax asparagine-rich protein (PvARP) by a straightforward approach using molecular biology and immunochemistry assays. The reactivity with sera from individuals infected with P. vivax indicates that it contains epitopes that are target of antibody response generated during natural exposure.
	8. 953 Accesses	Research Both infected and uninfected mosquitoes are attracted toward malaria infected birds Stéphane Cornet, Antoine Nicot, Ana Rivero, Sylvain Gandon Malaria Journal 2013, 12:179 (3 June 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Feeding behaviour of Plasmodium relictum-infected and non-infected Culex pipiens mosquitoes. The authors developed a convenient model for such research.
	9. 904 Accesses	Research Epidemiology of Plasmodium infections in Flores Island, Indonesia using real-time PCR Maria MM Kaisar, Taniawati Supali, Aprilianto E Wiria, Firdaus Hamid, Linda J Wammes, Erliyani Sartono, Adrian JF Luty, Eric AT Brienen, Maria Yazdanbakhsh, Lisette van Lieshout, Jaco J Verweij Malaria Journal 2013, 12:169 (24 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary This study provides a very useful addition to the growing body of evidence on the importance of asymptomatic carriers of malaria in hypo- to meso-endemic settings.
	10. 883 Accesses	Review A review of malaria vaccine clinical projects based on the WHO rainbow table Lauren Schwartz, Graham V Brown, Blaise Genton, Vasee S Moorthy Malaria Journal 2012, 11:11 (9 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary This review succeeds in its primary objective in presenting the most comprehensive review and, of necessity, is broad and goes into much more depth than might be expected. As such it complements the WHO spreadsheet, and is a valuable companion document.
	11. 852 Accesses	Methodology The parasite clearance curve NJ White Malaria Journal 2011, 10:278 (22 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The author presents a clear and concise introduction to the parasite clearance curve, which is important in determining the therapeutic response to anti-malarials, particularly artemisinin derivatives. Given the recent reports of emerging artemisinin resistance in Western Cambodia, this is a very timely report.
	12. 810 Accesses	Research A new world malaria map: Plasmodium falciparum endemicity in 2010 Peter W Gething, Anand P Patil, David L Smith, Carlos A Guerra, Iqbal RF Elyazar, Geoffrey L Johnston, Andrew J Tatem, Simon I Hay Malaria Journal 2011, 10:378 (20 December 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The paper represents a Herculean effort to provide an updated map of the global distribution of malaria, based on three key malariometric indices PfPR, PfEIR and PfRC and represents a unique contribution.
	13. 789 Accesses	Research Providing open access data online to advance malaria research and control Catherine L Moyes, William H Temperley, Andrew J Henry, Clara R Burgert, Simon I Hay Malaria Journal 2013, 12:161 (16 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A description of the construction of the Malaria Atlas Project's online data portal. It usefully details the data and associated products that the MAP team has made accessible to the global malaria community.
	14. 770 Accesses	Research A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China Duo-quan Wang, Zhi-gui Xia, Shui-sen Zhou, Xiao-nong Zhou, Ru-bo Wang, Qing-feng Zhang Malaria Journal 2013, 12:164 (17 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A paper that highlights the problem of insecticide resistance in malaria vectors in China.
	15. 769 Accesses	Research G6PD deficiency in Plasmodium falciparum and Plasmodium vivax malaria-infected Cambodian patients Nimol Khim, Christophe Benedet, Saorin Kim, Sim Kheng, Sovannaroth Siv, Rithea Leang, Soley Lek, Sinuon Muth, Nguon Chea, Char Chuor, Socheat Duong, Alexandra Kerleguer, Pety Tor, Pheaktra Chim, Lydie Canier, Benoit Witkowski, Walter RJ Taylor, Didier Ménard Malaria Journal 2013, 12:171 (28 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Reports the results of survey of G6PD deficiency, anaemia and haemoglobinopathies in malaria patients in Cambodia. The issue of G6PD deficiency is highly relevant in countries such as Cambodia, faced with the need to use primaquine to effectively deal with vivax malaria and to reduce transmission of falciparum, but where anxiety among doctors and nurses of primaquine-induced severe haemolysis in patients with G6PD deficiency is widespread.
	16. 740 Accesses	Research Submicroscopic Plasmodium falciparum malaria and low birth weight in an area of unstable malaria transmission in Central Sudan Amal H Mohammed, Magdi M Salih, Elhassan M Elhassan, Ahmed A Mohmmed, Salah E Elzaki, Badria B El-Sayed, Ishag Adam Malaria Journal 2013, 12:172 (28 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary An interesting and difficult-to-obtain data set from a case-control study of the relationship between Plasmodium falciparum infection during pregnancy and low birth weight in the delivered babies. This is important in view of the current controversy regarding the importance of submicroscopic infections on birth weight. This is a relevant issue as countries consider changing antenatal care policies from intermittent preventive treatment of malaria in pregnancy to intermittent screening and treatment of malaria in pregnancy.
	17. 734 Accesses	Reviews Plant-based insect repellents: a review of their efficacy, development and testing Marta Maia, Sarah J Moore Malaria Journal 2011, 10(Suppl 1):S11 (15 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18. 735 Accesses	Research Natural Plasmodium infection in monkeys in the state of Rondônia (Brazilian Western Amazon) Maisa S Araújo, Mariluce R Messias, Marivaldo R Figueiró, Luiz Herman S Gil, Christian M Probst, Newton M Vidal, Tony H Katsuragawa, Marco A Krieger, Luiz H Pereira da Silva, Luiz S Ozaki Malaria Journal 2013, 12:180 (3 June 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Describes a PCR-based survey of Plasmodium infections in monkeys in Rondonia. Nearly 200 monkey blood samples were screened with 18S rRNA based primers designed for this study, and some individual samples were followed up with more detailed amplification and sequencing. The data adds information to our understanding of simian Plasmodium in the Amazon.
	19. 725 Accesses	Research Hyperendemic malaria transmission in areas of occupation-related travel in the Peruvian Amazon Benjamin S Parker, Maribel Paredes Olortegui, Pablo Peñataro Yori, Karin Escobedo, David Florin, Silvia Rengifo Pinedo, Roldan Cardenas Greffa, Luis Capcha Vega, Hugo Rodriguez Ferrucci, William K Pan, Cesar Banda Chavez, Joseph M Vinetz, Margaret Kosek Malaria Journal 2013, 12:178 (31 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary The article identifies the primary vector and potential for transmission along a riverine system, as well as exportation of malaria to hypoendemic regions of the Iquitos area. The data confirm the focal nature of malaria transmission in the region and describe some of the factors that account for this pattern.
	20. 713 Accesses	Case study Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination Carlos J Chaccour, Kevin C Kobylinski, Quique Bassat, Teun Bousema, Chris Drakeley, Pedro Alonso, Brian D Foy Malaria Journal 2013, 12:153 (7 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A topic of high importance to the vector control community and reflects recent discussions on the current challenges in malaria prevention and control ¿ specifically, development of new tools for niche transmission settings (i.e., outdoors) where current interventions, such as ITNs and IRS may not be effective.
	21. 711 Accesses	Methodology Environmentally friendly tool to control mosquito populations without risk of insecticide resistance: the Lehmann's funnel entry trap Abdoulaye Diabaté, Etienne Bilgo, Roch K Dabiré, Fréderic Tripet Malaria Journal 2013, 12:196 (10 June 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary This study presents the results of the use of a funnel entry trap as an alternative tool to control mosquitoes. The development of novel control tools is highly needed and the study is a proof a concept of the use of the trap.
	22. 704 Accesses	Research Polymorphism of the parasite lactate dehydrogenase gene from Plasmodium vivax Korean isolates Hyun-Il Shin, Jung-Yeon Kim, Won-Ja Lee, Youngjoo Sohn, Sang-Wook Lee, Yoon-Joong Kang, Hyeong-Woo Lee Malaria Journal 2013, 12:166 (21 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Parasite lactate dehydrogenase (pLDH) is widely used in rapid diagnostic tests: the genetic variation of Korean isolates was analysed. The fact that the pLDH genes of 19 isolates of P. vivax were identical, except for one for SNP at nucleotide 456 indicates that this gene is relatively stable.
	23. 692 Accesses	Research Malaria and protective behaviours: is there a malaria trap? Jean-Claude Berthélemy, Josselin Thuilliez, Ogobara Doumbo, Jean Gaudart Malaria Journal 2013, 12:200 (13 June 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary This paper is about the theoretical existence of a malaria trap as well as the implications of this for the distribution of insecticide-treated nets. -
	24. 676 Accesses	Methodology A novel live-dead staining methodology to study malaria parasite viability Erica M Pasini, Denise van den Ierssel, Henri J Vial, Clemens HM Kocken Malaria Journal 2013, 12:190 (7 June 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary The authors used various dyes of different commercial sources to stain malaria parasites with the aim to differentially distinguish live from dead parasites. An underlying objective is to apply this technique in testing drug sensitivity of malaria parasite and to be used as a tool for checking quality of the long term culture of P. vivax.
	25. 637 Accesses	Research Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission Bernadette J Huho, Gerard F Killeen, Heather M Ferguson, Adriana Tami, Christian Lengeler, J Derek Charlwood, Aniset Kihonda, Japhet Kihonda, S Patrick Kachur, Thomas A Smith, Salim MK Abdulla Malaria Journal 2012, 11:118 (18 April 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A study of the impact of artesunate/SP use on oocyst/sporozoite carriage in mosquitoes. It is not unexpected that in an area of intense malaria transmission, with presumed large numbers of asymptomatic gametocyte carriers, that ACT does not result in a marked reduction in transmission indices. Whilst the result in not unexpected the methodology is thorough and is likely to be useful to others.