Malaria Journal | All articles

Submit a manuscript Register Contact us Follow
BioMed Central Follow
@malariajournal Support

Explore Malaria Journal

Advertisement

Articles

Supplements

Display/download options Articles per page: 25 | 50 | 100

Display options

Editor's summary Citation

Download options

Send
To

	All
		Research Dose–response tests and semi-field evaluation of lethal and sub-lethal effects of slow release pyriproxyfen granules (Sumilarv^®0.5G) for the control of the malaria vectors Anopheles gambiae sensu lato Oscar Mbare, Steven W Lindsay, Ulrike Fillinger Malaria Journal 2013, 12:94 (14 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Research has shown that larviciding can be an effective tool for integrated malaria vector control, but the uptake of this intervention has been hampered by the need to re-apply larvicides frequently. There is a need to explore persistent, environmentally friendly larvicides for malaria vector control and the efficacy of a 0.5% pyriproxyfen granule was assessed here for the control of major malaria vectors in sub-Saharan Africa.
		Research Imported malaria in Finland 2003-2011: prospective nationwide data with rechecked background information Heli Siikamäki, Pia Kivelä, Outi Lyytikäinen, Anu Kantele Malaria Journal 2013, 12:93 (14 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A prospective nationwide survey of imported malaria in Finland, where compliance data was double-checked.
		Research Ultrasonographic renal sizes, cortical thickness and volume in Nigerian children with acute falciparum malaria Omolola M Atalabi, Adebola E Orimadegun, Ademola J Adekanmi, Olusegun O Akinyinka Malaria Journal 2013, 12:92 (13 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary An ultrasonographic report of the changes in kidney volume in Nigerian children with complicated and uncomplicated malaria.
		Research Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase Natpasit Chaianantakul, Rachada Sirawaraporn, Worachart Sirawaraporn Malaria Journal 2013, 12:91 (12 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A study comparing the activities of P falciparum DHFR and TS proteins expressed with amino acid deletions from the N-terminal of the junction region of the bifunctional and single proteins in attempts to define the minimum functional area of the junction.
		Research Deforestation, agriculture and farm jobs: a good recipe for Plasmodium vivax in French Guiana Célia Basurko, Christophe Demattei, René Han-Sze, Claire Grenier, Michel Joubert, Mathieu Nacher, Bernard Carme Malaria Journal 2013, 12:90 (11 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The paper deals with a very important subject, which is the relationship between malaria and the environment. The study explores the spatio-temporal dynamics of vivax malaria in the village of Cacao in French Guiana using statistical methods to detect disease clusters.
		Research Two series of new semisynthetic triterpene derivatives: differences in anti-malarial activity, cytotoxicity and mechanism of action Gloria NS da Silva, Nicole RG Maria, Desirée C Schuck, Laura N Cruz, Miriam S de Moraes, Myna Nakabashi, Cedric Graebin, Grace Gosmann, Célia RS Garcia, Simone CB Gnoatto Malaria Journal 2013, 12:89 (9 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Paper describing the synthetic modification of two natural products to form a series of semi-synthetic derivatives with anti-malarial activity in vitro against a chloroquine-sensitive strain of parasite. Potential mechanisms of action, namely alteration of mitochondrion membrane potential and beta-hematin inhibition were investigated.
		Case report Hyperparasitaemic human Plasmodium knowlesi infection with atypical morphology in peninsular Malaysia Wenn-Chyau Lee, Pek-Woon Chin, Yee-Ling Lau, Lit-Chein Chin, Mun-Yik Fong, Chee-Jiek Yap, Raymond Supramaniam, Rohela Mahmud Malaria Journal 2013, 12:88 (6 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A case report which adds supportive information to current descriptions of severe knowlesi malaria, in this case with hyperparasitaemia.
		Research Environmental determinant of malaria cases among travellers Gaëtan Texier, Vanessa Machault, Meili Barragti, Jean-Paul Boutin, Christophe Rogier Malaria Journal 2013, 12:87 (4 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A vey detailed study of environmental influences that may be important in long-term exposure of non-immune visitors to the Ivory Coast. The authors correctly point out that the threat of malaria can be controlled by the compliant use of preventative measures and that this is often done badly.
		Case study Experience and challenges from clinical trials with malaria vaccines in Africa Grace Mwangoka, Bernhards Ogutu, Beverly Msambichaka, Tutu Mzee, Nahya Salim, Shubis Kafuruki, Maxmillian Mpina, Seif Shekalaghe, Marcel Tanner, Salim Abdulla Malaria Journal 2013, 12:86 (4 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The paper provides an important insight from an African research centre about lessons learned after an era of clinical trials experience. It touches upon very important issues such as sustainability of capacity built, among others.
		Research Design, implementation and evaluation of a national campaign to deliver 18 million free long-lasting insecticidal nets to uncovered sleeping spaces in Tanzania Sabine Renggli, Renata Mandike, Karen Kramer, Faith Patrick, Nick J Brown, Peter D McElroy, Wilhelmina Rimisho, Amina Msengwa, Ally Mnzava, Rose Nathan, Romanus Mtung’e, Rita Mgullo, Jane Lweikiza, Christian Lengeler Malaria Journal 2013, 12:85 (4 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Iimpressive accomplishments of Tanzania?s very ambitious universal coverage campaign, which is very timely as many sub-Saharan African countries are now implementing their own universal coverage campaigns.
		Research Characterizing microclimate in urban malaria transmission settings: a case study from Chennai, India Lauren J Cator, Shalu Thomas, Krijn P Paaijmans, Sangamithra Ravishankaran, Johnson A Justin, Manu T Mathai, Andrew F Read, Matthew B Thomas, Alex Eapen Malaria Journal 2013, 12:84 (2 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Environmental temperature is an important driver of malaria transmission dynamics. A pilot study conducted in the Indian city of Chennai in which temperatures were measured at predicted resting and transmission sites to better model a realistic extrinsic incubation period in various microclimates
		Research Spatio-temporal analysis of malaria within a transmission season in Bandiagara, Mali Drissa Coulibaly, Stanislas Rebaudet, Mark Travassos, Youssouf Tolo, Matthew Laurens, Abdoulaye K Kone, Karim Traore, Ando Guindo, Issa Diarra, Amadou Niangaly, Modibo Daou, Ahmadou Dembele, Mody Sissoko, Bourema Kouriba, Nadine Dessay, Jean Gaudart, Renaud Piarroux, Mahamadou A Thera, Christopher V Plowe, Ogobara K Doumbo Malaria Journal 2013, 12:82 (1 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Describes the spatial and temporal variation of Plasmodium falciparum infections in children from a rural population from Mali, based on a longitudinal study on malaria incidence in Bandiagara. The spatial and temporal variation of malaria incidence is mapped and interpolated. Clusters of low incidence are identified.
		Research The effect of an anti-malarial subsidy programme on the quality of service provision of artemisinin-based combination therapy in Kenya: a cluster-randomized, controlled trial Beth P Kangwana, Sarah V Kedenge, Abdisalan M Noor, Victor A Alegana, Andrew J Nyandigisi, Jayesh Pandit, Greg W Fegan, Jim E Todd, Robert W Snow, Catherine A Goodman Malaria Journal 2013, 12:81 (1 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary This important pharmacy survey indicates that there is much to do about training, supervision and follow-up for those dispensing anti-malarials and other drugs in Kenya and elsewhere in Africa.
		Research Diversity of the var gene family of Indonesian Plasmodium falciparum isolates Erma Sulistyaningsih, Loeki E Fitri, Thomas Löscher, Nicole Berens-Riha Malaria Journal 2013, 12:80 (27 February 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A very thorough analysis of DBL sequences derived from P. falciparum samples from Indonesia, in particular the DBLa and DBlb domains of the var genes are studied and related to disease severity and ICAM-1 binding.
		Research A controlled, parallel, cluster-randomized trial of community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso Alfred B Tiono, Alphonse Ouédraogo, Bernhards Ogutu, Amidou Diarra, Sam Coulibaly, Adama Gansané, Sodiomon B Sirima, Gregory O’Neil, Amitava Mukhopadhyay, Kamal Hamed Malaria Journal 2013, 12:79 (27 February 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Study of the impact of RDT-based screening and treatment on seasonal malaria in Burkina Faso.
		Research A dynamic model of some malaria-transmitting anopheline mosquitoes of the Afrotropical region. II. Validation of species distribution and seasonal variations Torleif M Lunde, Meshesha Balkew, Diriba Korecha, Teshome Gebre-Michael, Fekadu Massebo, Asgeir Sorteberg, Bernt Lindtjørn Malaria Journal 2013, 12:78 (25 February 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Validation of a mathematical model described earlier. Overall, the model gives a realistic representation of seasonal and year-to-year variability in mosquito densities and it can accurately predict the distribution of An. gambiae s.s. and An. arabiensis in sub-Saharan Africa. It may be used for seasonal and long-term predictions of changes in the burden of malaria.
		Research Effects of pyrethroid resistance on the cost effectiveness of a mass distribution of long-lasting insecticidal nets: a modelling study Olivier JT Briët, Melissa A Penny, Diggory Hardy, Taiwo S Awolola, Wim Van Bortel, Vincent Corbel, Roch K Dabiré, Josiane Etang, Benjamin G Koudou, Patrick K Tungu, Nakul Chitnis Malaria Journal 2013, 12:77 (25 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The paper shows that standard and combination LLINs are likely to be cost effective against malaria even in areas with strong pyrethroid resistance. There is a strong message to funders and national malaria control programmes not abandon LLINs as the control tool of choice, because of fears that they might no longer be effective due to resistance.
		Research Blood meal sources and entomological inoculation rates of anophelines along a highland altitudinal transect in south-central Ethiopia Abebe Animut, Meshesha Balkew, Teshome Gebre-Michael, Bernt Lindtjørn Malaria Journal 2013, 12:76 (23 February 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A good report on the Anopheles fauna found in three different villages located at three different altitudes ranging from 1,800 meters to 2,200 metres, showing the human/cattle blood meal preference for each species and the sporozoite rate and entomological inoculation rate for the vectors.
		Research Perception of malaria risk in a setting of reduced malaria transmission: a qualitative study in Zanzibar Julie A Bauch, Jessica J Gu, Mwinyi Msellem, Andreas Mårtensson, Abdullah S Ali, Roly Gosling, Kimberly A Baltzell Malaria Journal 2013, 12:75 (22 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A relevant study from Zanzibar, an area where malaria has dropped dramatically in recent years, investigates perceptions of malaria risks among key health staff and villagers in two districts on the islands of Pemba and Unguju.
		Methodology Improved assay to detect Plasmodium falciparum using an uninterrupted, semi-nested PCR and quantitative lateral flow analysis Serge Y Ongagna-Yhombi, Paul Corstjens, Eran Geva, William R Abrams, Cheryl A Barber, Daniel Malamud, Sungano Mharakurwa Malaria Journal 2013, 12:74 (22 February 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary An uninterrupted asymmetric single amplification specific semi-nested PCR assay in comparison with traditional nested PCR. This approach provides a basis for migration of the assay to a point-of-care microfluidic format.
		Research Performance of two rapid diagnostic tests for malaria diagnosis at the China-Myanmar border area Juan Yan, Nana Li, Xu Wei, Peipei Li, Zhenjun Zhao, Lili Wang, Siying Li, Xiaomei Li, Ying Wang, Shuying Li, Zhaoqing Yang, Bin Zheng, Guofa Zhou, Guiyun Yan, Liwang Cui, Yaming Cao, Qi Fan Malaria Journal 2013, 12:73 (22 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Rapid diagnostic tests have become an essential tool in the contemporary malaria control and management programmes in the world. This study aimed to evaluate the performance of two commonly used RDTs for malaria diagnosis in the China-Myanmar border area, compared to microscopy and PCR.
		Research Persistent foci of falciparum malaria among tribes over two decades in Koraput district of Odisha State, India Sudhansu Sahu, Kasinathan Gunasekaran, Perumal Vanamail, Purusothaman Jambulingam Malaria Journal 2013, 12:72 (21 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Results of an epidemiological survey performed in the state of Orissa, in an area where the population of which is predominantly tribal and where malaria is endemic at a relatively high intensity; the prevalence of malaria has increased over the 22 year period.
		Research Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids Marli C Lombard, David D N’Da, Christophe Tran Van Ba, Sharon Wein, Jennifer Norman, Lubbe Wiesner, Henri Vial Malaria Journal 2013, 12:71 (21 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary In vivo testing, using the Plasmodium vinckei mouse model, of synthesized artemisinin-aminoquinoline hybrids. A snapshot pharmacokinetic analysis was carried out on one of the hybrids to get an indication of the pharmacokinetic properties of this class of anti-malarial drugs.
		Research Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials Stephan Duparc, Isabelle Borghini-Fuhrer, Carl J Craft, Sarah Arbe-Barnes, Robert M Miller, Chang-Sik Shin, Lawrence Fleckenstein Malaria Journal 2013, 12:70 (21 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Compilation of efficacy and safety data from pooled analysis of six clinical trials with pyronaridine-artesunate. It offers a valuable comparison with other regimens.
		Research Networking the host immune response in Plasmodium vivax malaria Vitor RR Mendonça, Artur TL Queiroz, Fabrício M Lopes, Bruno B Andrade, Manoel Barral-Netto Malaria Journal 2013, 12:69 (21 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The clinical outcome of an infection is a consequence of the interaction of multiple factors - parasite, environmental and host factors. This study is a network analysis of different clinical presentations of vivax malaria to identify patterns of association between various candidate biomarkers and the clinical outcome.

	All
		Research Dose–response tests and semi-field evaluation of lethal and sub-lethal effects of slow release pyriproxyfen granules (Sumilarv^®0.5G) for the control of the malaria vectors Anopheles gambiae sensu lato Oscar Mbare, Steven W Lindsay, Ulrike Fillinger Malaria Journal 2013, 12:94 (14 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Research has shown that larviciding can be an effective tool for integrated malaria vector control, but the uptake of this intervention has been hampered by the need to re-apply larvicides frequently. There is a need to explore persistent, environmentally friendly larvicides for malaria vector control and the efficacy of a 0.5% pyriproxyfen granule was assessed here for the control of major malaria vectors in sub-Saharan Africa.
		Research Imported malaria in Finland 2003-2011: prospective nationwide data with rechecked background information Heli Siikamäki, Pia Kivelä, Outi Lyytikäinen, Anu Kantele Malaria Journal 2013, 12:93 (14 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A prospective nationwide survey of imported malaria in Finland, where compliance data was double-checked.
		Research Ultrasonographic renal sizes, cortical thickness and volume in Nigerian children with acute falciparum malaria Omolola M Atalabi, Adebola E Orimadegun, Ademola J Adekanmi, Olusegun O Akinyinka Malaria Journal 2013, 12:92 (13 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary An ultrasonographic report of the changes in kidney volume in Nigerian children with complicated and uncomplicated malaria.
		Research Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase Natpasit Chaianantakul, Rachada Sirawaraporn, Worachart Sirawaraporn Malaria Journal 2013, 12:91 (12 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A study comparing the activities of P falciparum DHFR and TS proteins expressed with amino acid deletions from the N-terminal of the junction region of the bifunctional and single proteins in attempts to define the minimum functional area of the junction.
		Research Deforestation, agriculture and farm jobs: a good recipe for Plasmodium vivax in French Guiana Célia Basurko, Christophe Demattei, René Han-Sze, Claire Grenier, Michel Joubert, Mathieu Nacher, Bernard Carme Malaria Journal 2013, 12:90 (11 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The paper deals with a very important subject, which is the relationship between malaria and the environment. The study explores the spatio-temporal dynamics of vivax malaria in the village of Cacao in French Guiana using statistical methods to detect disease clusters.
		Research Two series of new semisynthetic triterpene derivatives: differences in anti-malarial activity, cytotoxicity and mechanism of action Gloria NS da Silva, Nicole RG Maria, Desirée C Schuck, Laura N Cruz, Miriam S de Moraes, Myna Nakabashi, Cedric Graebin, Grace Gosmann, Célia RS Garcia, Simone CB Gnoatto Malaria Journal 2013, 12:89 (9 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Paper describing the synthetic modification of two natural products to form a series of semi-synthetic derivatives with anti-malarial activity in vitro against a chloroquine-sensitive strain of parasite. Potential mechanisms of action, namely alteration of mitochondrion membrane potential and beta-hematin inhibition were investigated.
		Case report Hyperparasitaemic human Plasmodium knowlesi infection with atypical morphology in peninsular Malaysia Wenn-Chyau Lee, Pek-Woon Chin, Yee-Ling Lau, Lit-Chein Chin, Mun-Yik Fong, Chee-Jiek Yap, Raymond Supramaniam, Rohela Mahmud Malaria Journal 2013, 12:88 (6 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A case report which adds supportive information to current descriptions of severe knowlesi malaria, in this case with hyperparasitaemia.
		Research Environmental determinant of malaria cases among travellers Gaëtan Texier, Vanessa Machault, Meili Barragti, Jean-Paul Boutin, Christophe Rogier Malaria Journal 2013, 12:87 (4 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A vey detailed study of environmental influences that may be important in long-term exposure of non-immune visitors to the Ivory Coast. The authors correctly point out that the threat of malaria can be controlled by the compliant use of preventative measures and that this is often done badly.
		Case study Experience and challenges from clinical trials with malaria vaccines in Africa Grace Mwangoka, Bernhards Ogutu, Beverly Msambichaka, Tutu Mzee, Nahya Salim, Shubis Kafuruki, Maxmillian Mpina, Seif Shekalaghe, Marcel Tanner, Salim Abdulla Malaria Journal 2013, 12:86 (4 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The paper provides an important insight from an African research centre about lessons learned after an era of clinical trials experience. It touches upon very important issues such as sustainability of capacity built, among others.
		Research Design, implementation and evaluation of a national campaign to deliver 18 million free long-lasting insecticidal nets to uncovered sleeping spaces in Tanzania Sabine Renggli, Renata Mandike, Karen Kramer, Faith Patrick, Nick J Brown, Peter D McElroy, Wilhelmina Rimisho, Amina Msengwa, Ally Mnzava, Rose Nathan, Romanus Mtung’e, Rita Mgullo, Jane Lweikiza, Christian Lengeler Malaria Journal 2013, 12:85 (4 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Iimpressive accomplishments of Tanzania?s very ambitious universal coverage campaign, which is very timely as many sub-Saharan African countries are now implementing their own universal coverage campaigns.
		Research Characterizing microclimate in urban malaria transmission settings: a case study from Chennai, India Lauren J Cator, Shalu Thomas, Krijn P Paaijmans, Sangamithra Ravishankaran, Johnson A Justin, Manu T Mathai, Andrew F Read, Matthew B Thomas, Alex Eapen Malaria Journal 2013, 12:84 (2 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Environmental temperature is an important driver of malaria transmission dynamics. A pilot study conducted in the Indian city of Chennai in which temperatures were measured at predicted resting and transmission sites to better model a realistic extrinsic incubation period in various microclimates
		Research Spatio-temporal analysis of malaria within a transmission season in Bandiagara, Mali Drissa Coulibaly, Stanislas Rebaudet, Mark Travassos, Youssouf Tolo, Matthew Laurens, Abdoulaye K Kone, Karim Traore, Ando Guindo, Issa Diarra, Amadou Niangaly, Modibo Daou, Ahmadou Dembele, Mody Sissoko, Bourema Kouriba, Nadine Dessay, Jean Gaudart, Renaud Piarroux, Mahamadou A Thera, Christopher V Plowe, Ogobara K Doumbo Malaria Journal 2013, 12:82 (1 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Describes the spatial and temporal variation of Plasmodium falciparum infections in children from a rural population from Mali, based on a longitudinal study on malaria incidence in Bandiagara. The spatial and temporal variation of malaria incidence is mapped and interpolated. Clusters of low incidence are identified.
		Research The effect of an anti-malarial subsidy programme on the quality of service provision of artemisinin-based combination therapy in Kenya: a cluster-randomized, controlled trial Beth P Kangwana, Sarah V Kedenge, Abdisalan M Noor, Victor A Alegana, Andrew J Nyandigisi, Jayesh Pandit, Greg W Fegan, Jim E Todd, Robert W Snow, Catherine A Goodman Malaria Journal 2013, 12:81 (1 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary This important pharmacy survey indicates that there is much to do about training, supervision and follow-up for those dispensing anti-malarials and other drugs in Kenya and elsewhere in Africa.
		Research Diversity of the var gene family of Indonesian Plasmodium falciparum isolates Erma Sulistyaningsih, Loeki E Fitri, Thomas Löscher, Nicole Berens-Riha Malaria Journal 2013, 12:80 (27 February 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A very thorough analysis of DBL sequences derived from P. falciparum samples from Indonesia, in particular the DBLa and DBlb domains of the var genes are studied and related to disease severity and ICAM-1 binding.
		Research A controlled, parallel, cluster-randomized trial of community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso Alfred B Tiono, Alphonse Ouédraogo, Bernhards Ogutu, Amidou Diarra, Sam Coulibaly, Adama Gansané, Sodiomon B Sirima, Gregory O’Neil, Amitava Mukhopadhyay, Kamal Hamed Malaria Journal 2013, 12:79 (27 February 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Study of the impact of RDT-based screening and treatment on seasonal malaria in Burkina Faso.
		Research A dynamic model of some malaria-transmitting anopheline mosquitoes of the Afrotropical region. II. Validation of species distribution and seasonal variations Torleif M Lunde, Meshesha Balkew, Diriba Korecha, Teshome Gebre-Michael, Fekadu Massebo, Asgeir Sorteberg, Bernt Lindtjørn Malaria Journal 2013, 12:78 (25 February 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Validation of a mathematical model described earlier. Overall, the model gives a realistic representation of seasonal and year-to-year variability in mosquito densities and it can accurately predict the distribution of An. gambiae s.s. and An. arabiensis in sub-Saharan Africa. It may be used for seasonal and long-term predictions of changes in the burden of malaria.
		Research Effects of pyrethroid resistance on the cost effectiveness of a mass distribution of long-lasting insecticidal nets: a modelling study Olivier JT Briët, Melissa A Penny, Diggory Hardy, Taiwo S Awolola, Wim Van Bortel, Vincent Corbel, Roch K Dabiré, Josiane Etang, Benjamin G Koudou, Patrick K Tungu, Nakul Chitnis Malaria Journal 2013, 12:77 (25 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The paper shows that standard and combination LLINs are likely to be cost effective against malaria even in areas with strong pyrethroid resistance. There is a strong message to funders and national malaria control programmes not abandon LLINs as the control tool of choice, because of fears that they might no longer be effective due to resistance.
		Research Blood meal sources and entomological inoculation rates of anophelines along a highland altitudinal transect in south-central Ethiopia Abebe Animut, Meshesha Balkew, Teshome Gebre-Michael, Bernt Lindtjørn Malaria Journal 2013, 12:76 (23 February 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A good report on the Anopheles fauna found in three different villages located at three different altitudes ranging from 1,800 meters to 2,200 metres, showing the human/cattle blood meal preference for each species and the sporozoite rate and entomological inoculation rate for the vectors.
		Research Perception of malaria risk in a setting of reduced malaria transmission: a qualitative study in Zanzibar Julie A Bauch, Jessica J Gu, Mwinyi Msellem, Andreas Mårtensson, Abdullah S Ali, Roly Gosling, Kimberly A Baltzell Malaria Journal 2013, 12:75 (22 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A relevant study from Zanzibar, an area where malaria has dropped dramatically in recent years, investigates perceptions of malaria risks among key health staff and villagers in two districts on the islands of Pemba and Unguju.
		Methodology Improved assay to detect Plasmodium falciparum using an uninterrupted, semi-nested PCR and quantitative lateral flow analysis Serge Y Ongagna-Yhombi, Paul Corstjens, Eran Geva, William R Abrams, Cheryl A Barber, Daniel Malamud, Sungano Mharakurwa Malaria Journal 2013, 12:74 (22 February 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary An uninterrupted asymmetric single amplification specific semi-nested PCR assay in comparison with traditional nested PCR. This approach provides a basis for migration of the assay to a point-of-care microfluidic format.
		Research Performance of two rapid diagnostic tests for malaria diagnosis at the China-Myanmar border area Juan Yan, Nana Li, Xu Wei, Peipei Li, Zhenjun Zhao, Lili Wang, Siying Li, Xiaomei Li, Ying Wang, Shuying Li, Zhaoqing Yang, Bin Zheng, Guofa Zhou, Guiyun Yan, Liwang Cui, Yaming Cao, Qi Fan Malaria Journal 2013, 12:73 (22 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Rapid diagnostic tests have become an essential tool in the contemporary malaria control and management programmes in the world. This study aimed to evaluate the performance of two commonly used RDTs for malaria diagnosis in the China-Myanmar border area, compared to microscopy and PCR.
		Research Persistent foci of falciparum malaria among tribes over two decades in Koraput district of Odisha State, India Sudhansu Sahu, Kasinathan Gunasekaran, Perumal Vanamail, Purusothaman Jambulingam Malaria Journal 2013, 12:72 (21 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Results of an epidemiological survey performed in the state of Orissa, in an area where the population of which is predominantly tribal and where malaria is endemic at a relatively high intensity; the prevalence of malaria has increased over the 22 year period.
		Research Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids Marli C Lombard, David D N’Da, Christophe Tran Van Ba, Sharon Wein, Jennifer Norman, Lubbe Wiesner, Henri Vial Malaria Journal 2013, 12:71 (21 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary In vivo testing, using the Plasmodium vinckei mouse model, of synthesized artemisinin-aminoquinoline hybrids. A snapshot pharmacokinetic analysis was carried out on one of the hybrids to get an indication of the pharmacokinetic properties of this class of anti-malarial drugs.
		Research Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials Stephan Duparc, Isabelle Borghini-Fuhrer, Carl J Craft, Sarah Arbe-Barnes, Robert M Miller, Chang-Sik Shin, Lawrence Fleckenstein Malaria Journal 2013, 12:70 (21 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Compilation of efficacy and safety data from pooled analysis of six clinical trials with pyronaridine-artesunate. It offers a valuable comparison with other regimens.
		Research Networking the host immune response in Plasmodium vivax malaria Vitor RR Mendonça, Artur TL Queiroz, Fabrício M Lopes, Bruno B Andrade, Manoel Barral-Netto Malaria Journal 2013, 12:69 (21 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The clinical outcome of an infection is a consequence of the interaction of multiple factors - parasite, environmental and host factors. This study is a network analysis of different clinical presentations of vivax malaria to identify patterns of association between various candidate biomarkers and the clinical outcome.