Table 4 |
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|
Prevalence of molecular markers associated with P. falciparum resistance to SP in IPTi intervention and non-intervention zone in Kolokani in December 2007 after one year of implementation. |
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|
No IPTi |
IPTi |
OR |
95% CI |
p |
|||
|
|
|||||||
|
Molecular Markers |
n |
Prevalence (95% CI) |
n |
Prevalence (95% CI) |
|||
|
|
|||||||
|
DHPS 437 |
432 |
19.4% (15.1 - 24.6) |
479 |
21.7% (17.4-26.7) |
1.15 |
0.59- 2.24 |
0.68 |
|
|
|||||||
|
DHPS 540 |
428 |
0.9% (0.2-3.1) |
474 |
1.0% (0.3-3.1) |
1.13 |
0.16-7.99 |
0.90 |
|
|
|||||||
|
DHFR 51 |
379 |
56.5% (50.1-62.6) |
402 |
51.0% (44.9-57.1) |
0.80 |
0.52-1.23 |
0.32 |
|
|
|||||||
|
DHFR 59 |
376 |
55.3% (48.9-61.5) |
402 |
51.0% (44.9-57.1) |
0.84 |
0.50-1.40 |
0.51 |
|
|
|||||||
|
DHFR 108 |
375 |
56.8% (50.4-63.0) |
392 |
47.7% (41.5-53.9) |
0.69 |
0.47-1.03 |
0.07 |
|
|
|||||||
|
Triple DHFR mutation (DHFR 51, 59 and 108) |
368 |
44.8% (38.5-51.3) |
384 |
38.5% (32.6-44.8) |
0.77 |
0.50-1.19 |
0.24 |
|
|
|||||||
|
Quadruple mutation (DHFR 51, 59 and 108 + DHPS 437) |
367 |
11.2% (7.6-16.0) |
379 |
11.6% (8.1-16.4) |
1.04 |
0.51-2.12 |
0.90 |
|
|
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|
Dicko et al. Malaria Journal 2010 9:9 doi:10.1186/1475-2875-9-9 |
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