Table 4

Association between mutations and tandem repeat region type of pvdhfr gene in P. vivax isolates from Afghanistan.

Repeat region type

pvdhfr

pvdhps

Nangarhar

Herat

I13L

P33L

F57I/L

S58R

T61M

S117N/T

I173L

A383G

A553G

n = 86

n = 85

A

I

P

F

S

T

N

I

A

A

2 (2.3%)

-

I

P

F

S

T

S

I

A

A

3 (3.5%)

8 (9.4%)

B

I

P

F

R

T

N

I

A

A

2 (2.3%)

1 (1.2%)

I

P

F

S

T

N

I

A

A

8 (9.3%)

1(1.2%)

I

P

F

S

T

S

I

A

A

61 (71%)

67 (78.8%)

I

P

F

SR

T

S

I

A

A

3 (3.5%)

-

I

P

F

S

T

SN

I

A

A

2 (2.3%)

3 (3.6%)

I

P

F

S

T

N

I

G

A

-

1(1.2%)

C

I

P

F

S

T

S

I

A

A

4 (4.6%)

2 (2.3%)

A/B

I

P

F

S

T

S

I

A

A

-

2 (2.3%)

A/B/C

I

P

F

S

T

SN

I

A

A

1 (1.2%)

-

Zakeri et al. Malaria Journal 2010 9:75   doi:10.1186/1475-2875-9-75