Figure 2.

Frequency distribution of the combination pvdhfr/pvdhps haplotypes obtained from 171 isolates collected from Herat province in north-west and Nangarhar province in eastern of Afghanistan. All six haplotypes are indicated as A to F in the Figure. Mutated amino acids are boldfaced. A) I₁₃P₃₃F₅₇S₅₈T₆₁S₁₁₇I₁₇₃/A₃₈₃A₅₅₃ B) I₁₃P₃₃F₅₇S₅₈T₆₁N₁₁₇I₁₇₃/A₃₈₃A₅₅₃ C) I₁₃P₃₃F₅₇S₅₈T₆₁SN₁₁₇I₁₇₃/A₃₈₃A₅₅₃ D) I₁₃P₃₃F₅₇R₅₈T₆₁N₁₁₇I₁₇₃/A₃₈₃A₅₅₃ E) I₁₃P₃₃F₅₇ SR₅₈T₆₁S₁₁₇I₁₇₃/A₃₈₃A₅₅₃ F) I₁₃P₃₃F₅₇R₅₈T₆₁N₁₁₇I₁₇₃/G₃₈₃A₅₅₃.