Table 3

P. berghei oocyst number/mosquito and development stage proportions after a secondary, treated blood meal.

Treatment

Replication

Stage of development*

Total (CI95%)

Examined mosquitoes

s1 (%)

s2 (%)

s3 (%)

control

1

25 (38)

23 (37)

12 (25)

70 (50 - 98)

27

2

15 (33)

12 (31)

13 (36)

54 (42 - 70)

92

NA 50 mg/kg

1

10 (36)

10 (36)

8 (28)

31 (19 - 49)

23

2

30 (42)

21 (33)

11 (25)

82 (68 - 100)

112

AZA 50 mg/kg

1

19 (34)

20 (35)

18 (31)

61 (40 - 93)

27

Secondary blood meals were carried out on mice treated with the indicated products and doses on day 7 after mosquito infection. Oocysts were evaluated on day 3 after the secondary blood meal (day 10 post infection). *s1: immature oocysts, before the formation of sporoblasts (fig. 1A); s2: immature oocysts, with visible sporoblasts and budding sporozoites (fig. 1 B1 - B2); s3: mature oocysts containing fully developed sporozoites (fig. 1C). Geometric means, only positive mosquitoes included.

Lucantoni et al. Malaria Journal 2010 9:66   doi:10.1186/1475-2875-9-66