Research
Efficacy of non-artemisinin- and artemisinin-based combination therapies for uncomplicated falciparum malaria in Cameroon
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* Corresponding author: Leonardo K Basco lkbasco@yahoo.fr
1 Unité de Recherche 77 Paludologie Afro-tropicale, Institut de Recherche pour le Développement (IRD) and Laboratoire de Recherche sur le Paludisme, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), BP 288, Yaoundé, Cameroon
2 Université de Yaoundé I, Ecole Nationale Supérieure Polytechnique, Département de Mathématiques et Sciences Physiques, BP 8390, Yaoundé, Cameroon
3 Université Paris Descartes, Laboratoire de Mathématiques Appliquées Paris 5 (MAP5), Unité Mixte de Recherche 8145, Centre National de la Recherche Scientifique, 45 rue des Saints Pères, 75006 Paris, France
4 Centre de Formation et de Recherche en Médecine et Santé Tropicale, Faculté de Médecine, 13916 Marseille, France
Malaria Journal 2010, 9:56 doi:10.1186/1475-2875-9-56
Published: 19 February 2010Additional files
Additional file 1:
Table S1: Pre-treatment clinical and laboratory characteristics of enrolled children who completed the 14-day or 28-day follow-up. 1 Patients were followed-up for 14 days in studies conducted in 2003 and for 28 days in studies performed in 2005-2007. Patients assigned to artesunate-mefloquine group were followed for 42 days. AQ, amodiaquine; SP, sulphadoxine-pyrimethamine; AS, artesunate; MQ, mefloquine; AM, artemether; LM, lumefantrine; CD, chlorproguanil-dapsone; DH, dihydroartemisinin; PP, piperaquine. 2 Number of patients enrolled (number of patients analyzed, with complete 14- [in 2003] or 28-day [in 2005-2007] follow-up, in parentheses). 3 The numbers of children aged > 60 months old (and/or adults for Maroua) are 18/57 in Garoua 2003 AQ, 16/58 in Garoua 2003 SP, 27/58 in Garoua 2003 AQ-SP, and 18/64 (28.1%) in Maroua (none at other study sites). Garoua and Maroua are situated in northern Cameroon where malaria transmission is seasonal. 4 The following number of patients had > 200,000 asexual parasites/μL of blood: 2 (1 in AQ group and 1 in SP group) in Yaoundé 2003; 5 (2 in AQ group and 3 in SP group) in Bertoua 2003; 3 (2 in AQ group and 1 in AQ-SP group) in Garoua 2003; 10 (5 in AQ group, 4 in AS-AQ group, and 1 in AS-SP group) in Yaoundé 2005; 1 in Maroua; 4 (2 in AQ-SP group, 2 in AS-MQ group) in Yaoundé 2006a; 5 (4 in AS-AQ group, and 1 in AM-LM group) in Yaoundé 2006b; 7 (5 in AS-SP group and 2 in AS-CD group) in Yaoundé 2007a; and 11 (5 in DH-PP group and 6 in AS-AQ group) in Yaoundé 2007b.
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