Figure 7.

Parasitaemia (A) and survival (B) of control mice (n = 10) and mice administered complete S. mansoni egg extract (SmEA; n = 10) or egg extract from which IPSE/alpha-1 was removed (SmEA ΔIPSE/alpha-1; n = 10), by i.v. injection, on days 7 and 0 before PbA infection and days 3 and 6 post-infection. Control mice were injected with PBS. *Parasitaemia was slightly lower in mice treated with SmEA or SmEA ΔIPSE/alpha-1 compared to control mice, on days 7-10 post-infection (p < 0.05, t-test). **A significant delay to death was seen between control and treated mice (p < 0.05, t-test), but not between the treated groups (p = 0.2, t-test). Shaded areas denote the period of CM susceptibility and death.