Assessment of two malaria rapid diagnostic tests in children under five years of age, with follow-up of false-positive pLDH test results, in a hyperendemic falciparum malaria area, Sierra Leone
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* Corresponding author: Sibylle Gerstl sgerstl@aol.com
Malaria Journal 2010, 9:28 doi:10.1186/1475-2875-9-28
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BioMed Central: 3 citations
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Research article
Lisa K Allen, Jennifer M Hatfield, Giselle DeVetten, Jeremy C Ho, Mange Manyama BMC Infectious Diseases 2011, 11:308 (3 November 2011) |
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Research
Deus S Ishengoma, Filbert Francis, Bruno P Mmbando, John PA Lusingu, Pamela Magistrado, Michael Alifrangis, Thor G Theander, Ib C Bygbjerg, Martha M Lemnge Malaria Journal 2011, 10:176 (26 June 2011) This paper examines the sensitivity and specificity of RDT versus microscopy in two different types of study – a longitudinal study of febrile illness and a community cross sectional in Tanzania. The authors show that RDT reduced the number of malaria treatments given, but question the sensitivity of the tests.
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Research
Prozone in malaria rapid diagnostics tests: how many cases are missed? Philippe Gillet, Annelies Scheirlinck, Jocelijn Stokx, Anja De Weggheleire, Hélder S Chaúque, Oreana DJV Canhanga, Benvindo T Tadeu, Carla DD Mosse, Armindo Tiago, Samuel Mabunda, Cathrien Bruggeman, Emmanuel Bottieau, Jan Jacobs Malaria Journal 2011, 10:166 (15 June 2011) A study testing whether the prozone effect has a significant effect on the performance of malaria RDTs in "in the real world". The authors report that four of the six RDTs used in the study with fresh samples showed only a "weak" prozone effect in a minority of the samples, predominantly those with high parasitemia. Two kits produced worrisome prozone effects.
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