Table 1 |
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Diagnostic performance of fluorescent microscopy (CyScope®) and the lateral-flow reagent strip (Paracheck-Pf®) using light microscopy (double reads) as gold-standard. |
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FLUORESCENT MICROSCOPY V. LIGHT MICROSCOPY |
PARACHECK-PF V. LIGHT MICROSCOPY |
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468 ADULTS AND 836 CHILDREN |
546 ADULTS AND 951 CHILDREN |
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Adults |
Sensitivity (%) |
86.7 (79.3 - 92.2) |
91.9 (85.9 - 95.9) |
|
Specificity (%) |
38.8 (33.6 - 44.1) |
98.1 (96.2 - 99.2) |
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|
PPV (%) |
32.8 (27.7 - 38.3) |
93.9 (88.4 - 97.3) |
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|
NPV (%) |
89.4 (83.4 - 93.8) |
97.3 (95.3 - 98.7) |
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|
|
|
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Children |
Sensitivity (%) |
92.1 (89.6 - 94.1) |
98.4 (97.2 - 99.2) |
|
Specificity (%) |
28.6 (22.8 - 34.9) |
96.2 (93.1 - 98.2) |
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|
PPV (%) |
77.1 (73.9 - 80.2) |
98.5 (97.3 - 99.3) |
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|
NPV (%) |
57.9 (48.3 - 67.1) |
95.8 (92.7 - 97.9) |
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|
|
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Values are expressed in % and brackets indicate CI95; PPV stands for positive predictive value, NPV stands for negative predictive value |
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Sousa-Figueiredo et al. Malaria Journal 2010 9:245 doi:10.1186/1475-2875-9-245 |
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