Research
Analysis of innate defences against Plasmodium falciparum in immunodeficient mice
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* Corresponding author: Pierre Druilhe druilhe@pasteur.fr
- † Equal contributors
1 Laboratoire de Parasitologie Bio-Médicale, Institut Pasteur, 28, rue du Dr Roux, 75015 Paris, France
2 Current Address; James Mitchell Laboratory, Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA, USA
3 Department of Molecular Cell Biology, VU University Medical Center, 1007 MB Amsterdam, the Netherlands
Malaria Journal 2010, 9:197 doi:10.1186/1475-2875-9-197
Published: 9 July 2010Additional files
Additional file 1:
Comparison of the effects of three anti-PMN monoclonal antibodies. (A) Peripheral blood parasitaemia in 3 different NOD/SCID mice treated either with NIMP-R14 (plain circle, dotted line), RB6-8C5 (open circle) or 1A8 (black square) monoclonal antibody at 10 mg/kg. Black arrows represent injection of HuRBC + clo-clip and one of the three anti-PMN antibodies. (B) Peritoneal blood parasitaemia obtained in the NOD/SCID mice treated with different anti-PMN. (C) Percentages of CD11b+ Ly-6G+ PMN in mouse peripheral blood following repeated administration of the anti-PMN monoclonal antibodies.
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