Table 7 |
||||||||||
|
Estimated diagnostic accuracy of RDT for malaria - attributable fever during the low and high transmission seasons |
||||||||||
|
Age |
Febrile |
Malaria-attributable |
Not malaria-attributable |
SE |
SP |
PPV |
NPV |
|||
|
(years) |
N |
TP (a) |
FN (b) |
FP (c) |
TN (d) |
|
|
|
|
|
|
|
||||||||||
|
Low transmission (dry) season |
||||||||||
|
< 1 |
143 |
4.4 |
0.2 |
35.9 |
102.4 |
95 |
74 |
11 |
99.8 |
|
|
1 - 4 |
299 |
8.8 |
0.5 |
88.2 |
201.5 |
94 |
70 |
9 |
99.7 |
|
|
5 - 14 |
130 |
4.0 |
0.3 |
39.9 |
85.7 |
93 |
68 |
9 |
99.7 |
|
|
15+ |
280 |
2.5 |
0.3 |
46.2 |
230.9 |
89 |
83 |
5 |
99.9 |
|
|
|
||||||||||
|
All |
852 |
19.8 |
1.3 |
210.3 |
620.6 |
94 |
75 |
9 |
99.8 |
|
|
|
||||||||||
|
High transmission (rainy) season |
||||||||||
|
< 1 |
159 |
113.6 |
3.3 |
25.5 |
16.7 |
97 |
40 |
82 |
84 |
|
|
1 - 4 |
504 |
293.2 |
7.7 |
130.2 |
72.9 |
97 |
36 |
69 |
90 |
|
|
5 - 14 |
275 |
113.4 |
4.0 |
99.6 |
58.1 |
97 |
37 |
53 |
94 |
|
|
15+ |
379 |
45.7 |
1.4 |
74.4 |
257.4 |
97 |
78 |
38 |
99.4 |
|
|
|
||||||||||
|
All |
1317 |
565.8 |
16.4 |
329.7 |
405.1 |
97 |
55 |
63 |
96 |
|
|
|
||||||||||
|
N: number of febrile patients in each age-parasite density combination. TP, FN, FP, TN: expected number of true positives, false negatives, false positives and true negatives of the RDT for clinical malaria diagnosis among the N febrile cases in each age-parasite density combination. Estimates obtained from N, AF and Prob RDT + (see methods). Numbers presented are rounded to 1 decimal place; actual calculations based on a better numerical precision. SE, SP, PPV, NPV: estimated sensitivity, specificity, positive predictive value, negative predictive value of RDT for clinical malaria. |
||||||||||
|
Bisoffi et al. Malaria Journal 2010 9:192 doi:10.1186/1475-2875-9-192 |
||||||||||
