Table 2 |
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|
Characterization of the patients with severe vivax malaria. |
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|
Clinical presentation at admission |
P. vivax diagnosis |
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|
|
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|
Patient No. |
Gender |
Age (y) |
Major manifestation |
Secondary manifestation |
Nested PCR |
Microscopy |
Outcome |
|
|
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|
1 |
M |
15 |
Oliguria |
Hypotension, splenomegaly |
+ |
+ |
Recovered |
|
2 |
M |
17 |
Respiratory failure |
Hypotension |
+ |
+ |
Recovered |
|
3 |
F |
9 |
Respiratory failure |
Hypotension |
+ |
+ |
Died |
|
4 |
M |
21 |
Severe anaemia |
Hypotension, splenomegaly |
+ |
+ |
Recovered |
|
5 |
M |
22 |
Severe anaemia |
Hypotension |
+ |
+ |
Recovered |
|
6 |
M |
32 |
Anuric renal failure |
Hypotension, splenomegaly |
+ |
+ |
Died |
|
7 |
F |
41 |
Respiratory failure |
Hypotension, Jaundice |
+ |
+ |
Died |
|
8 |
F |
15 |
Severe anaemia |
Splenomegaly |
+ |
+ |
Recovered |
|
9 |
M |
15 |
Anuric renal failure |
Hypotension, Jaundice |
+ |
+ |
Died |
|
10 |
M |
17 |
Severe anaemia |
Splenomegaly |
+ |
+ |
Recovered |
|
11 |
F |
13 |
Jaundice |
Splenomegaly |
+ |
+ |
Recovered |
|
12 |
F |
26 |
Jaundice |
Hypotension |
+ |
+ |
Recovered |
|
13 |
M |
32 |
Respiratory failure |
Hypotension |
+ |
+ |
Recovered |
|
14 |
F |
27 |
Seizure |
Jaundice |
+ |
+ |
Recovered |
|
15 |
M |
42 |
Oliguria |
Hypotension |
+ |
+ |
Recovered |
|
16 |
F |
38 |
Jaundice |
Hypotension |
+ |
+ |
Recovered |
|
17 |
F |
54 |
Respiratory failure |
Hypotension |
+ |
+ |
Died |
|
18 |
M |
24 |
Severe anaemia |
Hypotension |
+ |
+ |
Recovered |
|
19 |
M |
22 |
Respiratory failure |
Jaundice |
+ |
+ |
Died |
|
|
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|
Data regarding major and secondary manifestations were obtained from medical records and/or through the clinical exam at the hospital admission. Oliguria was defined as estimated urinary output less than 400 mL/24 h and anuric renal failure as urinary output below 100 mL/24 h. Severe anaemia was defined as haemoglobin levels below 7 g/dL and jaundice by clinical exam and bilirubin levels above 2.0. Hypotension was defined as the presence of related symptoms with blood pressure below 100 × 40 mmHg. Respiratory failure was defined as tachypnea, shortness of breath, mental confusion clinical signs of hypoxaemia (central and/or peripheral cyanosis). |
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|
Andrade et al. Malaria Journal 2010 9:13 doi:10.1186/1475-2875-9-13 |
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