Figure 4.

Kinetic of immunologic indicators during antimalarial treatment in individuals with severe vivax disease. (A) IFN-gamma/IL-10 ratios and (B) TNF plasma levels were estimated before treatment (at admission to the Hospital) and after seven days of in-hospital care in individuals with severe vivax infection who achieved cure (n = 13). Wilcoxon matched pairs test was performed to calculate the statistical significance. P values are plotted in each graph.