Table 6 |
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|
The frequency of adverse events mild to moderate grades from day 1 to day 7 (related or not) after treatment initiation |
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|
AS-SMP 3 days (A) (N = 476) |
AS-SMP 24 hours (B) (N = 458) |
AL 3 days (C) (N = 450) |
P-value |
|
|
|
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|
Vomiting – n (%) |
22 (4.6) |
32 (7.0) |
10 (2.2) |
0.003 |
|
Nausea-n (%) |
15 (3.2) |
19 (4.2) |
14 (3.1) |
0.6 |
|
Headache – n (%) |
5 (1.1) |
10 (2.2) |
7 (1.6) |
0.4 |
|
Weakness – n (%) |
11 (2.3) |
5 (1.1) |
2 (0.4) |
0.04 |
|
Anorexia – n (%) |
16 (3.4) |
11 (2.4) |
17 (3.8) |
0.5 |
|
Dizziness – n (%) |
13 (2.7) |
14 (3.1) |
10 (2.2) |
0.7 |
|
Diarrhea – n (%) |
3 (0.6) |
15 (3.3) |
6 (1.3) |
0.006 |
|
Rash – n (%) |
3 (0.6) |
5 (1.1) |
1 (0.2) |
0.3 |
|
Abdominal pain – n (%) |
21 (4.4) |
21 (4.6) |
17 (3.8) |
0.8 |
|
Others* – n (%) |
15 (3.2) |
10 (2.2) |
12 (2.7) |
0.7 |
|
Total – n (%) |
124 (26.1) |
142 (31.0) |
96 (21.3) |
0.004 |
|
|
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|
Data are no. (%) of participants with the sign or symptom from day 1 to day 7 after treatment * Others are: infections (skin, respiratory, intestinal...) pains... |
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|
Sagara et al. Malaria Journal 2009 8:63 doi:10.1186/1475-2875-8-63 |
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