Table 7

Trends in chloroquine sensitivity profiles during periods of co-administration of antihistamines with chloroquine or use of sub-therapeutic dosage regimen in patients from a private hospital in Ibadan, south-west Nigeria

Year

Frequency of co-administration of antihistamine

Frequency of prescription of Full course regimen

Frequency of sub-therapeutic regimen

Reported chloroquine sensitivity


1983 (N = 289)

74.7%

93.1%

6.9%

100% [19,20]


1985 (N = 298)

80.0%

98.3%

1.7%


1987 (N = 295)

84.4%

96.3%

3.7%

100% [21]


1989 (N = 220)

72.3%

97.3%

2.7%


1992 (N = 258)

67.4%

78.3%

21.7%

85% [22]


1995 (N = 243)

48.6%

72.8%

27.2%


1997 (N = 241)

51.9%

56.4%

43.6%

<40%([3]


Gbotosho et al. Malaria Journal 2009 8:313   doi:10.1186/1475-2875-8-313

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