Table 6 |
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|
Chi-square Hardy-Weinberg equilibrium tests for SNP data acquired by sequencing. |
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|
Cambodia |
Tanzania |
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|
|
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|
SNP |
χ2 |
P |
χ2 |
P |
|
|
||||
|
CYP2A6*2 |
N.A. |
N.A. |
||
|
CYP2B6*5 |
10.86 |
< 0.01 |
N.A. |
|
|
CYP2B6*6 |
0.28 |
0.60 |
1.81 |
0.18 |
|
CYP2C8*3 |
N.A. |
N.A. |
||
|
CYP2C9*3 |
2.94 |
0.08 |
N.A. |
|
|
CYP2C9*5 |
N.A. |
0.14 |
0.71 |
|
|
CYP2C19*3 |
N.A. |
N.A. |
||
|
CYP2D6*4 |
N.A. |
15.75 |
< 0.01 |
|
|
CYP2D6*10 (100C>T) |
1.39 |
0.24 |
1.34 |
0.25 |
|
CYP2D6*10 (4180G>C) |
2.01 |
0.16 |
1.24 |
0.27 |
|
CYP2D6*17 (1023C>T) |
N.A. |
0.05 |
0.82 |
|
|
CYP2D6*17 (2850C>T) |
0.24 |
0.62 |
4.94 |
0.03 |
|
CYP3A4*1B |
0.10 |
0.75 |
0.04 |
0.84 |
|
CYP3A5*3 |
0.64 |
0.42 |
0.04 |
0.84 |
|
N.A.T2*5 |
0.10 |
0.75 |
0.01 |
0.92 |
|
N.A.T2*6 |
0.48 |
0.49 |
1.07 |
0.30 |
|
N.A.T2*7 |
0.01 |
0.92 |
0.14 |
0.71 |
|
N.A.T2*14 |
N.A. |
5.02 |
0.03 |
|
|
|
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|
χ2 indicates the result from the Hardy-Weinberg equilibrium test, P the one-tailed P-value, and N.A. that Chi-square could not be calculated because the allele frequency was either 0% or 100%. |
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|
Hodel et al. Malaria Journal 2009 8:285 doi:10.1186/1475-2875-8-285 |
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