Table 1 |
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The panel of modified MSP119 antigens |
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Amino acid substitutions in the primary sequence |
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|
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|
Position(s) |
Wildtype residue |
Variant residue |
|
|
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|
Single amino acid |
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|
|
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|
6 |
Gln |
Ile |
|
|
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|
14 |
Gln |
Arg |
|
|
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|
32 |
Leu |
Arg |
|
|
||
|
33 |
Asn |
Ile |
|
|
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|
40 |
Lys |
Ile |
|
|
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|
Multiple amino acids |
||
|
|
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|
12+28 |
Cys+Cys |
Ile+Trp |
|
|
||
|
34+39 |
Tyr+Asp |
Ser+Thr |
|
|
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|
43+48 |
Glu+Thr |
Leu+Lys |
|
|
||
|
15+27+31+43 |
Asn+Glu+Leu+Glu |
Arg+Tyr+Arg+Leu |
|
|
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|
27+31+34+43 |
Glu+Leu+Tyr+Glu |
Tyr+Arg+Ser+Leu |
|
|
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|
Position in the sequence is numbered from the N-terminus of MSP119 |
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|
Okafor et al. Malaria Journal 2009 8:263 doi:10.1186/1475-2875-8-263 |
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