Table 4 |
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|
Risk of Recrudescence due to Low Antibody Levels to Blood Stage Malarial Antigens in Total Population (N = 268) |
|||
|
Parasite Isolate/Antigen |
Odds Ratio* |
95% CI |
P value |
|
|
|
|
|
|
VSA E8B |
0.68 |
0.50-0.94 |
0.02 |
|
VSA A4 |
0.61 |
0.40-0.92 |
0.02 |
|
VSA HCD6 |
0.28 |
0.08-0.96 |
0.04 |
|
|
|
|
|
|
AMA-1 |
1 |
0.58-1.75 |
0.98 |
|
MSP2 type 3D7 |
1.08 |
0.57-2.07 |
0.81 |
|
MSP2 type FC27 |
1.08 |
0.57-2.07 |
0.81 |
|
|
|||
|
* All results of antibodies to Variant Surface Antigens were adjusted for CD4 count on day 0 in a multivariate logistic regression model. Additional risk factors for recrudescence were high parasite density (AOR:2.64; P = 0.04), anemia (AOR:4.67; P = 0.0001) and SP treatment (AOR:7.98; P = 0.001). |
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|
Van Geertruyden et al. Malaria Journal 2009 8:258 doi:10.1186/1475-2875-8-258 |
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