Table 4 |
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|
Accumulation of MP in placenta does not affect IL-12 production by APC upon TLR3 and TLR4 stimulation. |
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|
Monocytes |
MDC |
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|
|
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|
Parameter median (± interquartile) |
stimulus |
MP-Negative |
MP-Positive |
MP-Negative |
MP-Positive |
|
|
|||||
|
IL-12 (% positive cells) |
LPS |
3.55 ± (4.13) |
2.70 ± (3.15) |
3.13 ± (3.72) |
2.13 ± (1.72) |
|
Poly:IC |
2.33 ± (3.37) |
3.99 ± (4.49) |
1.95 ± (4.01) |
2.38 ± (3.09) |
|
|
|
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|
Intracytoplasmic IL-12 production by APC upon TLR3 and TLR4 stimulation was analysed on 43 cord blood samples; 31 from MP-negative women and 12 MP-positive women. All comparisons between MP-negative and MP-positive women were not significant. |
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|
Fievet et al. Malaria Journal 2009 8:251 doi:10.1186/1475-2875-8-251 |
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