PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria
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* Corresponding author: Sandrine Houzé sandrine.houze@bch.aphp.fr
Malaria Journal 2009, 8:211 doi:10.1186/1475-2875-8-211
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Research
Arsène Ratsimbasoa, Harintsoa Ravony, Jeanne-Aimée Vonimpaisomihanta, Rogelin Raherinjafy, Martial Jahevitra, Rabenja Rapelanoro, Jean Rakotomanga, Denis Malvy, Pascal Millet, Didier Ménard Malaria Journal 2012, 11:85 (25 March 2012) A study of test performance characteristics of rapid malaria diagnostics when used by community health workers. Consistent with past studies, RDTs appear to be accurate in the hands of minimally-trained CHWs and add value for management of fever in among children in remote settings without access to quality-controlled laboratory facilities.
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Louise Marquart, Alice Butterworth, James S McCarthy, Michelle L Gatton Malaria Journal 2012, 11:74 (19 March 2012) The results of the model indicate that good quality RDTs should be able to detect parasites on the first day of symptoms, and that the persistence of the antigen will cause the tests to remain positive for at least seven days after treatment.
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Research
Use of a pLDH-based dipstick in the diagnostic and therapeutic follow-up of malaria patients in Mali Amed Ouattara, Safiatou Doumbo, Renion Saye, Abdoul H Beavogui, Boubacar Traoré, Abdoulaye Djimdé, Amadou Niangaly, Kassoum Kayentao, Mouctar Diallo, Ogobara K Doumbo, Mahamadou A Thera Malaria Journal 2011, 10:345 (24 November 2011) Although several papers have addressed the accuracy of pLDH-based rapid tests, this paper also deals with the important issue of the potential use of RDTs for treatment follow-up.
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