Table 5 |
|||||||||||||
|
Haemoglobin and haematocrit values and changes between Day 0–14, and Day 0–28 (AS&AQ and comparators) |
|||||||||||||
|
Haemoglobin |
N |
Day 0 |
Day 7 |
Paired relative difference |
Paired difference |
t-value |
P-value |
||||||
|
mean |
sd |
Mean |
sd |
% |
lower 95%CI |
upper 95%CI |
mean |
sd |
|||||
|
|
|||||||||||||
|
Ndiaye |
ASAQ |
766 |
10.1 |
2.29 |
9.6 |
2.02 |
-5% |
-3% |
-7% |
-0.50 |
1.24 |
-11.07 |
0.000 |
|
AL |
482 |
9.9 |
2.26 |
9.7 |
1.92 |
-2% |
1% |
-4% |
-0.18 |
1.40 |
-2.89 |
0.004 |
|
|
Epicentre |
AS+AQ |
249 |
10.3 |
1.76 |
9.8 |
1.74 |
-4% |
-1% |
-7% |
-0.42 |
1.19 |
-5.50 |
0.000 |
|
AS+SP |
248 |
10.2 |
1.88 |
9.7 |
1.66 |
-5% |
-2% |
-8% |
-0.51 |
1.20 |
-6.71 |
0.000 |
|
|
|
|||||||||||||
|
Haematocrit |
N |
Day 0 |
Day 7 |
Paired relative difference |
Paired difference |
t-value |
P-value |
||||||
|
mean |
sd |
Mean |
sd |
% |
lower 95%CI |
upper 95%CI |
mean |
sd |
|||||
|
|
|||||||||||||
|
Sirima |
AS+AQ |
136 |
25.5 |
4.93 |
27.4 |
4.57 |
7% |
4% |
10% |
1.87 |
3.75 |
5.83 |
0.000 |
|
ASAQ |
149 |
25.8 |
4.52 |
27.5 |
4.25 |
6% |
4% |
9% |
1.64 |
3.12 |
6.40 |
0.000 |
|
|
|
|||||||||||||
|
Haematocrit |
N |
Day 0 |
Day 14 |
Paired relative difference |
Paired difference |
t-value |
P-value |
||||||
|
mean |
sd |
Mean |
sd |
% |
lower 95%CI |
upper 95%CI |
mean |
sd |
|||||
|
|
|||||||||||||
|
Karema |
AQ+SP |
251 |
31.5 |
5.35 |
34.49 |
3.70 |
9% |
8% |
11% |
2.95 |
4.95 |
9.44 |
0.000 |
|
AS+AQ |
247 |
31.0 |
5.49 |
33.99 |
3.66 |
10% |
8% |
11% |
3.02 |
4.88 |
9.72 |
0.000 |
|
|
DP |
247 |
31.5 |
4.91 |
33.43 |
3.62 |
6% |
4% |
8% |
1.90 |
5.24 |
5.70 |
0.000 |
|
|
|
|||||||||||||
|
Haemoglobin |
N |
Day 0 |
Day 28 |
Paired relative difference |
Paired difference |
t-value |
P-value |
||||||
|
mean |
sd |
mean |
sd |
% |
lower 95%CI |
upper 95%CI |
mean |
sd |
|||||
|
|
|||||||||||||
|
Ndiaye |
ASAQ |
762 |
10.1 |
2.31 |
11.04 |
1.76 |
9% |
7% |
11% |
0.96 |
1.74 |
15.48 |
0.000 |
|
AL |
471 |
9.96 |
2.26 |
10.93 |
1.59 |
10% |
7% |
12% |
0.97 |
1.69 |
12.52 |
0.000 |
|
|
Epicentre |
AS+AQ |
798 |
9.60 |
1.93 |
10.68 |
1.59 |
11% |
9% |
13% |
1.08 |
1.68 |
18.18 |
0.000 |
|
AS+SP |
801 |
9.54 |
1.94 |
10.64 |
1.50 |
12% |
10% |
13% |
1.10 |
1.66 |
18.77 |
0.000 |
|
|
|
|||||||||||||
|
Haematocrit |
N |
Day 0 |
Day 28 |
Paired relative difference |
Paired difference |
t-value |
P-value |
||||||
|
mean |
sd |
mean |
sd |
% |
lower 95%CI |
upper 95%CI |
mean |
Sd |
|||||
|
|
|||||||||||||
|
Sirima |
AS+AQ |
259 |
26.7 |
6.00 |
31.38 |
4.50 |
18% |
16% |
20% |
4.70 |
5.85 |
12.92 |
0.000 |
|
ASAQ |
258 |
26.7 |
5.59 |
31.33 |
5.02 |
17% |
15% |
20% |
4.66 |
5.78 |
12.94 |
0.000 |
|
|
|
|||||||||||||
|
Note. SD: standard deviation; CI: confidence interval |
|||||||||||||
|
Zwang et al. Malaria Journal 2009 8:203 doi:10.1186/1475-2875-8-203 |
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