Figure 2.

Anti-MSP-1p42 antisera prevent the rupture of heterologous and homologous clones, FVO and CAMP/FUP, but not 3D7. Cultures were set up with schizont stage pRBCs in the presence of sera (at 20% v/v) from rabbits immunized with either MSP-1p42(3D7) (FMP1) or MSP-1p42(FVO) (FMP003) emulsified in FA. Sera from rabbits immunized with reduced/alkylated MSP-1p42(R/A)/FA were used as the negative control. Triplicate blood smears were prepared from each culture 6 hrs after invasion was completed. Micrographs of representative parasites were taken at 1000× magnification.