Table 1 |
||||||
|
The availability of some key features in malaria web resources relevant to drug target and lead identification. |
||||||
|
Discovery |
PlasmoDB |
PlasmoMap |
MDT |
TDR |
PlasmoID |
|
|
|
||||||
|
Orthology |
✓ |
✓ |
✗ |
✗ |
✓ |
✗ |
|
Functional Annotation |
✓ |
✓ |
✗ |
✓ |
✓ |
✓ |
|
Metabolism |
✓ |
✓ |
✗ |
✗ |
✓ |
✗ |
|
Structure |
✓ |
✓ |
✗ |
✓ |
✓ |
✗ |
|
Protein Interactions |
✓ |
✓ |
✓ |
✗ |
✗ |
✓ |
|
Druggability |
✗ |
✗ |
✗ |
✗ |
✓ |
✗ |
|
Ligand Interactions |
✓ |
✗ |
✗ |
✗ |
✓ |
✗ |
|
Host/pathogen |
✓ |
✗ |
✗ |
✗ |
✗ |
✗ |
|
Expression |
✗* |
✓ |
✗ |
✗ |
✓ |
✗ |
|
Chemo-informatics |
✓ |
✗ |
✗ |
✗ |
✗ |
✗ |
|
Literature |
✗* |
✓ |
✗ |
✓ |
✓ |
✗ |
|
|
||||||
|
* In development |
||||||
|
Joubert et al. Malaria Journal 2009 8:178 doi:10.1186/1475-2875-8-178 |
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