Table 3

Comparison of sero-conversion rates derived from RDT and from filter paper blood-spots

RDT

Filter paper



Seroconversion rate

(95% CI)

Seroconversion rate

(95% CI)


Korogwe

MSP-11–19

0.042

(0.039

0.046)

0.040

(0.037

0.044)

AMA-1

0.129

(0.117

0.143)

0.127

(0.116

0.140)

Same

MSP-11–19

previous

0.018

(0.014

0.022)

0.019

(0.016

0.022)

current

0.011

(0.007

0.016)

0.011

(0.007

0.016)

AMA-1

previous

0.049

(0.040

0.060)

0.068

(0.058

0.080)

current

0.017

(0.011

0.024)

0.010

(0.006

0.016)


Age sero-prevalence data were used to fit a catalytic conversion model [2] for data from RDT and filter paper for each combination of study area and antigen. As prevalence plots from Same indicated a recent drop in infection intensity, both previous and current estimates of sero-conversion rate are presented.

Williams et al. Malaria Journal 2009 8:168   doi:10.1186/1475-2875-8-168

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