Table 3 |
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|
Comparison of sero-conversion rates derived from RDT and from filter paper blood-spots |
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|
RDT |
Filter paper |
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|
|
|
|||||||
|
Seroconversion rate (95% CI) |
Seroconversion rate (95% CI) |
|||||||
|
|
||||||||
|
Korogwe |
MSP-11–19 |
0.042 |
(0.039 |
0.046) |
0.040 |
(0.037 |
0.044) |
|
|
AMA-1 |
0.129 |
(0.117 |
0.143) |
0.127 |
(0.116 |
0.140) |
||
|
Same |
MSP-11–19 |
previous |
0.018 |
(0.014 |
0.022) |
0.019 |
(0.016 |
0.022) |
|
current |
0.011 |
(0.007 |
0.016) |
0.011 |
(0.007 |
0.016) |
||
|
AMA-1 |
previous |
0.049 |
(0.040 |
0.060) |
0.068 |
(0.058 |
0.080) |
|
|
current |
0.017 |
(0.011 |
0.024) |
0.010 |
(0.006 |
0.016) |
||
|
|
||||||||
|
Age sero-prevalence data were used to fit a catalytic conversion model [2] for data from RDT and filter paper for each combination of study area and antigen. As prevalence plots from Same indicated a recent drop in infection intensity, both previous and current estimates of sero-conversion rate are presented. |
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|
Williams et al. Malaria Journal 2009 8:168 doi:10.1186/1475-2875-8-168 |
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