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Resolution: standard / high Figure 1.
A: Thoracic CT scan. Multiple confluent ground glass-infiltrates in both lungs due to Aspergillus fumigatus. B and C: Bronchoscopic findings. B: Sharply circumscribed lesion of the carina tracheae of the upper left lobe, extending
into the upper lobe bronchus. C: Extensive necrosis of the bronchial wall extending into the periphery up to segment
2 of the upper right lobe. D-G: Histological findings of the transbronchial biopsy. D: Overview of the biopsy specimen, HE stain, primary magnification × 5. The black
box indicates the area shown in E, primary magnification × 20: PAS staining showing extensive invasive growth of hyphae
into the bronchial wall (black arrows). F: Mycelia of Aspergillus fumigatus with dichotomy branching (black arrows) with inflammatory infiltrates and necrosis
(white arrows), PAS stain, primary magnification × 10. G: Extensive fungal growth with partially septated hyphae (black arrows), PAS stain,
primary magnification × 20.
Eckerle et al. Malaria Journal 2009 8:167 doi:10.1186/1475-2875-8-167 |