Table 3 |
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|
OHCT (nM) inhibits growth of P. falciparum gametocytes* |
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|
OHCT (Stage I and II) |
Chloroquine (Stage I and II) |
OHCT (Stage III and IV) |
Chloroquine (Stage III and IV) |
|
|
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|
(IC50) 22 ± 3.4 |
394 ± 127.0 |
36 ± 9.0 |
944 ± 92.0 |
|
(IC90) 174 ± 5.4 |
1520 ± 27.5 |
226 ± 49.3 |
2109 ± 85.2 |
|
|
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*IC50 and IC90 values (nM) represent the mean ± SE of duplicate experiments, each performed in duplicate (vehicle and 8 concentrations per experiment |
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Mayer et al. Malaria Journal 2009 8:139 doi:10.1186/1475-2875-8-139 |
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