Table 5 |
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|
Haplotype frequencies of the FcγRIIa 131 R/H*, CRP -286 C/T/A, CRP -717 C/T and CRP +1444 T/C |
||||||||||||
|
Mali |
||||||||||||
|
FcγRIIa131R/H CRP-286C/T/A |
CRP-286C/T/A CRP-717C/T |
CRP-286C/T/A CRP+1444T/C |
FcγRIIa131R/H CRP-286C/T/A CRP-717C/T |
CRP-286C/T/A CRP-717C/T CRP+1444T/C |
FcγRIIa131R/H CRP-286C/T/A CRP+1444T/C |
FcγRIIa131R/H CRP-286C/T/A CRP-717C/T CRP+1444T/C |
||||||
|
|
||||||||||||
|
Reference haplotype |
HA |
AC |
AC |
HAC |
ACC |
HAC |
HACC |
|||||
|
|
||||||||||||
|
N |
HA |
RA |
AT |
AC |
HAT |
RAT |
ATC |
HAC |
HATC |
RATC |
||
|
Non-Fulani |
159 |
0.20 |
0.19 |
0.39 |
0.39 |
0.20 |
0.19 |
0.39 |
0.21 |
0.20 |
0.19 |
|
|
Fulani |
164 |
0.09 |
0.09 |
0.18 |
0.18 |
0.09 |
0.09 |
0.18 |
0.7 |
0.09 |
0.09 |
|
|
OR |
2.57 |
2.26 |
2.79 |
2.79 |
2.58 |
2.29 |
2.79 |
3.6 |
2.6 |
2.28 |
||
|
P-value |
0.0001 |
0.0006 |
1 × 10-8 |
1 × 10-8 |
0.0001 |
0.0005 |
1 × 10-8 |
1 × 10-8 |
0.0001 |
0.0004 |
||
|
|
||||||||||||
|
Sudan |
||||||||||||
|
|
||||||||||||
|
N |
HA |
RA |
AT |
AC |
HAT |
RAT |
ATC |
HAT |
RAC |
HATC |
RATC |
|
|
Non-Fulani |
100 |
0.21 |
0.18 |
0.41 |
0.41 |
0.22 |
0.18 |
0.41 |
0.25 |
0.17 |
0.24 |
0.17 |
|
Fulani |
225 |
0.13 |
0.08 |
0.21 |
0.21 |
0.13 |
0.08 |
0.21 |
0.12 |
0.08 |
0.13 |
0.09 |
|
OR |
1.88 |
2.52 |
2.65 |
2.66 |
2.05 |
2.6 |
2.65 |
2.33 |
2.24 |
2.19 |
2.42 |
|
|
P-value |
0.007 |
0.0003 |
0.0001 |
0.0001 |
0.03 |
0.006 |
0.0001 |
0.005 |
0.03 |
0.01 |
0.02 |
|
|
|
||||||||||||
|
* The data for the FcγRIIa 131 R/H from Mali was obtained from Israelsson et al [7], and from Sudan from Nasr et al [30] |
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|
Israelsson et al. Malaria Journal 2009 8:136 doi:10.1186/1475-2875-8-136 |
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