Table 1 |
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|
Target antigen combinations in commercially available RDTs. Adapted from [34]. |
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|
RDT type |
Target antigens |
Possible results |
|
|
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|
I |
HRP2 |
No Pf |
|
Pf |
||
|
Invalid |
||
|
|
||
|
II |
HRP2 |
No malaria |
|
Aldolase (all species) |
Pf or mixed |
|
|
Pv, Po, and/or Pm |
||
|
Invalid |
||
|
|
||
|
III |
HRP2 |
No malaria |
|
pLDH (all species) |
Pf or mixed |
|
|
Pv, Po, and/or Pm |
||
|
Invalid |
||
|
|
||
|
IV |
pLDH (falciparum-specific) |
No malaria |
|
pLDH (all species) |
Pf or mixed |
|
|
Invalid |
||
|
|
||
|
V |
pLDH (falciparum-specific) |
No malaria |
|
pLDH (vivax-specific) |
Pf |
|
|
Pv |
||
|
Pf + Pv |
||
|
Invalid |
||
|
|
||
|
VI |
HRP2 |
No malaria |
|
pLDH (falciparum-specific) |
Pf or mixed |
|
|
pLDH (vivax-specific) |
Pf + Pv, +/- Po and/or Pm |
|
|
Pf +/- Po and/or Pm |
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|
Pv +/- Po and/or Pm |
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|
Po and/or Pm |
||
|
Invalid |
||
|
|
||
|
VII |
Aldolase (all species) |
No malaria |
|
Pf, Pv, Po and/or Pm |
||
|
Invalid |
||
|
|
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|
Perkins and Bell Malaria Journal 2008 7(Suppl 1):S5 doi:10.1186/1475-2875-7-S1-S5 |
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