Table 2 |
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|
The number of targets suggested for further study using experimental structural elucidation techniques in each priority category (PC, ranked 1 – 6) after the relevant elimination step. |
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| Priority Class (PC) |
PDB E-value range |
Nr of proteins |
Tm + disorder |
CC+LC+SP |
a |
b |
|
|
||||||
| PC1 |
No PDB matches |
139 |
11 |
8 |
1 |
7 |
| PC2 |
E-value > 10 |
174 |
15 |
11 |
3 |
8 |
| PC3 |
10 >= E-value > 5 |
352 |
34 |
31 |
9 |
22 |
| PC4 |
5 >= E-value > 3 |
332 |
35 |
19 |
5 |
14 |
| PC5 |
3 >= E-value > 1 |
810 |
88 |
51 |
12 |
39 |
| PC6 |
1 >= E-value > 0.5 |
529 |
60 |
58 |
10 |
48 |
|
|
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|
Tm+disorder refers to the amount of proteins in each group after the transmembrane and disorder filtering step. CC+LC+SP refers to the proteins in each group after coiled-coils, low complexity and signal peptide filtering step. Group a indicates proteins containing a Pfam functional domain. Group b indicates proteins without a Pfam functional domain. |
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|
Joubert and Joubert Malaria Journal 2008 7:90 doi:10.1186/1475-2875-7-90 |
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