Table 1

A summary of selected features calculated for annotated proteins in Plasmodium falciparum (a total of 5,411 proteins were analysed).

Feature
Occurrence

BLAST vs. PDB hits with at least 25% identity
27%
Hits vs. Pfam with E-value < 1 × 10-15
32%
No Pfam hits
43%
Threading Z score > 3.95
8%
One or more predicted coiled-coil regions
10%
Predicted to be transported out of the RBC (Pexel)
5%
Predicted to contain at least one transmembrane helix
30%
Predicted small molecule binding by SMID
22%
Protein-protein interaction by yeast-two hybrid results
15%
Predicted ≤ 40% disorder or no regular secondary structure
60%
Mean percentage low complexity per sequence
16%

Joubert and Joubert Malaria Journal 2008 7:90   doi:10.1186/1475-2875-7-90

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