How antimalarial drug resistance affects post-treatment prophylaxis
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Correspondence: Nicholas J White nickw@tropmedres.ac
Malaria Journal 2008, 7:9 doi:10.1186/1475-2875-7-9
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Ongoing challenges in the management of malaria Gilbert Kokwaro Malaria Journal 2009, 8(Suppl 1):S2 (12 October 2009) |
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Robin Kobbe, Philipp Klein, Samuel Adjei, Solomon Amemasor, William Thompson, Hanna Heidemann, Maja V Nielsen, Julia Vohwinkel, Benedikt Hogan, Benno Kreuels, Martina Bührlen, Wibke Loag, Daniel Ansong, Jürgen May Malaria Journal 2008, 7:261 (19 December 2008) Numerous trials have demonstrated high efficacy and safety of artemisinin-based combination therapy (ACT) under supervised treatment but looking how these treatments are applied unsupervised are scarce. Unobserved AL and ASAQ treatment showed high adequate clinical and parasitological responses, though AL was inferior in preventing late clinical failures.
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Monitoring and evaluation of malaria in pregnancy – developing a rational basis for control Bernard J Brabin, Marian Warsame, Ulrika Uddenfeldt-Wort, Stephanie Dellicour, Jenny Hill, Sabine Gies Malaria Journal 2008, 7(Suppl 1):S6 (11 December 2008) |
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Jürgen May, Samuel Adjei, Wibke Busch, Julian J Gabor, Saadou Issifou, Robin Kobbe, Benno Kreuels, Bertrand Lell, Norbert G Schwarz, Ohene Adjei, Peter G Kremsner, Martin P Grobusch Malaria Journal 2008, 7:198 (1 October 2008) The observation that the IPTi effect is mainly therapeutic and prophylactic might limit the selection of drugs eligible for IPTi to those that are long-acting. The unique property of SP as an inexpensive, one-dose anti-malaria drug favours SP, provided that it is not used as first line drug for treating malaria in the same area.
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