Table 1 |
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|
Clinical characteristics of the study participants |
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| CATEGORY |
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|
|
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| CHARACTERISTIC |
HC |
MM |
CMS |
CMNS |
|
|
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| Total number of subjects |
25 |
48 |
48 |
12 |
| Adults (≥ 18 yr) |
20 |
33 |
32 |
7 |
| Children (< 18 yr) |
5 |
15 |
16 |
5 |
| No of males |
18 |
28 |
34 |
6 |
| No of females |
7 |
20 |
14 |
6 |
| Median age (yr) |
22 ± 14 |
19 ± 14 |
25 ± 19 |
20 ± 16 |
| Mean Glasgow Coma Score |
14 |
14 |
6.7 ± 2.3 |
5.08 ± 2.2 |
| Seizures |
0 |
0 |
16 |
8 |
| Geomean parasitaemia (pRBC/mm3) |
0 |
1594 ± 426.6 |
4166 ± 650.9 |
1336 ± 386.2 |
| Geomean haemoglobin (g/dL) |
10.1 ± 0.40 |
9.17 ± 0.38 |
7.94 ± 0.37 |
6.82 ± 0.73 |
| Tribal population |
4 |
4 |
12 |
4 |
| Non-tribal population |
21 |
44 |
36 |
8 |
| Renal failure |
0 |
0 |
7 |
2 |
| Geomean duration of admission (days) |
N/A |
3.5 |
6.4 |
1.8 |
|
|
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|
Clinical study characteristics of the study participants in Jabalpur, India. HC – healthy controls, MM – mild malaria, CMS – cerebral malaria survivors, CMNS – cerebral malaria non-survivors. Relevant clinical data and information (such as duration of coma and seizures) were recorded for each patient from physician's records. Venous blood samples from children (2 – 5 ml) and adults (10 ml) were collected soon after enrolment into the study at the hospital from HC, MM, CMS, and CMNS groups prior to commencement of anti-malarial treatment or transfusions. Plasma was separated after centrifugation in Becton-Dickinson cell preparation tubes and aliquoted and frozen at -80°C for long-term storage. |
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|
Jain et al. Malaria Journal 2008 7:83 doi:10.1186/1475-2875-7-83 |
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