|
Parasitaemias of Plasmodium berghei ANKA-infected C57BL/6 mice, as % of parasitized red blood cell. |
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| Number of sporozoites per mouse |
Day of infection |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
10 |
14 |
19 |
|
|
|
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| Control |
50,000 |
Number of mice |
9 |
9 |
9 |
9 |
9 |
2 |
2 |
2 |
2 |
2 |
| ob/+ |
Mean parasitaemia |
0.000 |
0.011 |
0.221 |
1.61 |
3.01 |
2.83 |
3.42 |
7.37 |
32.4 |
39.9 |
|
| Standard deviation |
-- |
0.006 |
0.109 |
0.29 |
1.07 |
1.38 |
0.44 |
3.09 |
21.2 |
7.8 |
||
| Obese |
50,000 |
Number of mice |
5 |
5 |
5 |
5 |
5 |
5 |
5 |
5 |
5 |
5 |
| ob/ob |
Mean parasitaemia |
0.000 |
0.014 |
0.110 |
1.57 |
3.34 |
3.83 |
4.81 |
4.83 |
11.2 |
18.3 |
|
| Standard deviation |
-- |
0.009 |
0.113 |
0.40 |
0.40 |
0.94 |
1.35 |
1.16 |
6.07 |
5.78 |
||
| Obese |
100,000 |
Number of mice |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
| ob/ob |
Mean parasitaemia |
0.000 |
0.027 |
0.321 |
1.96 |
3.94 |
4.61 |
3.81 |
4.16 |
10.8 |
23.9 |
|
| Standard deviation |
-- |
0.025 |
0.155 |
0.51 |
0.96 |
0.85 |
1.35 |
0.28 |
6.12 |
5.11 |
||
|
Results of the first experimental series of infection, comparing the doses of injected sporozoites. | ||||||||||||
Robert et al. Malaria Journal 2008 7:81 doi:10.1186/1475-2875-7-81 |
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