Malaria Journal

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Distribution of knock-down resistance mutations in Anopheles gambiae molecular forms in west and west-central Africa

Federica Santolamazza, Maria Calzetta, Josiane Etang, Elena Barrese, Ibrahima Dia, Adalgisa Caccone, Martin J Donnelly, Vincenzo Petrarca, Frederic Simard, Joao Pinto and Alessandra della Torre*

Malaria Journal 2008, 7:74 doi:10.1186/1475-2875-7-74

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Aging partially restores the efficacy of malaria vector control in insecticide-resistant populations of Anopheles gambiae s.l. from Burkina Faso

Christopher M Jones, Antoine Sanou, Wamdaogo M Guelbeogo, N'Fale Sagnon, Paul C D Johnson, Hilary Ranson Malaria Journal 2012, 11:24 (23 January 2012)

The main finding here is that older mosquitoes are more susceptible to insecticides. This has important implications for understanding the epidemiological impact of resistance in field-based vector control interventions.

Research article   Open Access

Kdr-based insecticide resistance in Anopheles gambiae s.s populations in Cameroon: spread of the L1014F and L1014S mutations

Philippe Nwane, Josiane Etang, Mouhamadou Chouaїbou , Jean Toto, Rémy Mimpfoundi, Frédéric Simard BMC Research Notes 2011, 4:463 (28 October 2011)

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Dynamics of insecticide resistance in malaria vectors in Benin: first evidence of the presence of L1014S kdr mutation in Anopheles gambiae from West Africa

Innocent Djègbè, Olayidé Boussari, Aboubakar Sidick, Thibaud Martin, Hilary Ranson, Fabrice Chandre, Martin Akogbéto, Vincent Corbel Malaria Journal 2011, 10:261 (12 September 2011)

Pyrethroid and DDT resistance is widespread in malaria vector in Benin and both metabolic and target site resistance are implicated. Resistance was not correlated with a change of malaria species and/or molecular forms. The L1014S kdr allele was first identified in wild population of An. gambiae s.s and An. arabiensis hence confirming the expansion of pyrethroid resistance alleles in Africa.

Research   Open Access

Comparative analyses reveal discrepancies among results of commonly used methods for Anopheles gambiae molecular form identification

Federica Santolamazza, Beniamino Caputo, Maria Calzetta, José L Vicente, Emiliano Mancini, Vincenzo Petrarca, João Pinto, Alessandra della Torre Malaria Journal 2011, 10:215 (2 August 2011)

The results reveal that the PCR and PCR-RFLP approaches most commonly utilized to identify A. gambiae M and S forms are not fully interchangeable, as usually assumed. There are operational suggestions on the choice of the most convenient method for large-scale M- and S-form identification.

Research article   Open Access

Large-scale RNAi screen of G protein-coupled receptors involved in larval growth, molting and metamorphosis in the red flour beetle

Hua Bai, Fang Zhu, Kapil Shah, Subba Palli BMC Genomics 2011, 12:388 (1 August 2011)

Epilogue   Open Access

SIT for African malaria vectors: Epilogue

Harold Townson Malaria Journal 2009, 8(Suppl 2):S10 (16 November 2009)

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Trends in DDT and pyrethroid resistance in Anopheles gambiae s.s. populations from urban and agro-industrial settings in southern Cameroon

Philippe Nwane, Josiane Etang, Mouhamadou Chouaibou, Jean Toto, Clément Kerah-Hinzoumbé, Rémy Mimpfoundi, Herman Awono-Ambene, Frédéric Simard BMC Infectious Diseases 2009, 9:163 (30 September 2009)

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Status of insecticide susceptibility in Anopheles gambiae s.l. from malaria surveillance sites in The Gambia

Martha Betson, Musa Jawara, Taiwo Awolola Malaria Journal 2009, 8:187 (5 August 2009)

A survey of resistance to DDT and pyrethroid compounds in mosquito populations from six locations in The Gambia: the strengths of this study are its good average sample sizes per population and the good geographical spread of its collection sites.

Research   Open Access

A randomized, open-label, comparative efficacy trial of artemether-lumefantrine suspension versus artemether-lumefantrine tablets for treatment of uncomplicated Plasmodium falciparum malaria in children in western Kenya

Elizabeth A Juma, Charles O Obonyo, Willis S Akhwale, Bernhards R Ogutu Malaria Journal 2008, 7:262 (22 December 2008)

The limitations of administering hard tablets to young children have motivated this study: the two formulations appear to be comparable

Research   Open Access

Insecticide resistance in Anopheles gambiae from south-western Chad, Central Africa

Clément Kerah-Hinzoumbé, Mallaye Péka, Philippe Nwane, Issa Donan-Gouni, Josiane Etang, Albert Samè-Ekobo, Frédéric Simard Malaria Journal 2008, 7:192 (29 September 2008)

Original data on insecticide resistance in Anopheles gambiae from Chad, as well as information on species and form composition of the A. gambiae complex, which had not been investigated before in the area.

Research   Open Access

Evidence of increasing Leu-Phe knockdown resistance mutation in Anopheles gambiae from Niger following a nationwide long-lasting insecticide-treated nets implementation

Cyrille Czeher, Rabiou Labbo, Ibrahim Arzika, Jean-Bernard Duchemin Malaria Journal 2008, 7:189 (25 September 2008)

The results clearly indicate an increase in kdr frequency in the region over a three-year period, with suggestions that it may be attributable, directly or indirectly, to a large-scale LLIN programme.

Research   Open Access

Anopheles gambiae complex along The Gambia river, with particular reference to the molecular forms of An. gambiae s.s

Beniamino Caputo, Davis Nwakanma, Musa Jawara, Majidah Adiamoh, Ibrahima Dia, Lassana Konate, Vincenzo Petrarca, David J Conway, Alessandra della Torre Malaria Journal 2008, 7:182 (22 September 2008)

Dynamics of members of the Anopheles gambiae complex in relation to spatial or seasonal bio-ecological conditions across The Gambia River, as well as human biting indexes. The relative rates of M/S hybrids in collected samples reflects gene flow between M and S molecular forms in the study areas.