Table 1 |
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Parasitaemia and anaemia data in primary P. chabaudi AS or CB infections of BALB/c mice. |
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|
CLONE |
Experiment 1 |
Experiment 2 |
Experiment 3 |
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|
AS |
CB |
AS |
CB |
AS |
CB |
|
|
|
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|
AS |
CB |
AS |
CB |
AS |
CB |
|
|
Peak Parasite Number (×109 /ml) (1) |
3.9 ± 0.2 |
4.0 ± 0.5 |
1.5 ± 0.1 |
1.4 ± 0.2 |
2.1 ± 0.2 |
2.6 ± 0.3 |
|
Day of Peak Parasite Number (2) |
10.8 ± 0.2 |
9.2 ± 0.2 |
9.0 ± 0.3 |
9.4 ± 0.4 |
7.0 ± 0.5 |
7.4 ± 0.4 |
|
Parasite Load ((pRBC × 109/ml)days) (1) |
13.1 ± 1.3 |
16.4 ± 2.8 |
5.1 ± 0.6 |
3.1 ± 0.3 |
7.1 ± 0.5 |
6.0 ± 0.4 |
|
Peak % of pRBC (1,3) |
30.1 ± 1.8 |
42.6 ± 0.9 |
23.3 ± 2.8 |
31.8 ± 1.9 |
33.4 ± 2.7 |
43.9 ± 3.6 |
|
Day of peak % of pRBC (1,3) |
10.8 ± 0.2 |
9.2 ± 0.2 |
10.8 ± 0.2 |
10.6 ± 0.4 |
8.4 ± 0.4 |
8.2 ± 0.4 |
|
Maximum RBC loss (×109 /ml) (1,3) |
7.4 ± 0.4 |
9.1 ± 0.5 |
11.5 ± 1.4 |
13.6 ± 0.9 |
9.2 ± 0.4 |
9.4 ± 0.3 |
|
Day of greatest loss in RBC (1) |
11.6 ± 0.2 |
10.2 ± 0.4 |
11.2 ± 0.4 |
11.6 ± 0.5 |
9.6 ± 0.2 |
8.8 ± 0.4 |
|
Maximum Hg drop (mg/ml) (2) |
54.8 ± 12.6 |
152.8 ± 22.8 |
210.4 ± 11.0 |
219.0 ± 9.8 |
230.4 ± 6.5 |
242.1 ± 4.7 |
|
Day of greatest Hg drop (1,3) |
12.0 ± 0.8 |
10.4 ± 0.2 |
12.0 ± 0 |
11.6 ± 0.5 |
9.8 ± 0.4 |
9.0 ± 0.4 |
|
|
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|
The values represent the averages ± SEM from 5 animals 1) Significant difference in magnitude between experiments (P < 0.05) 2) Significant difference in clonal behaviour between experiments (P < 0.05) 3) Significant difference between clones (P < 0.05) |
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|
Lamb and Langhorne Malaria Journal 2008 7:68 doi:10.1186/1475-2875-7-68 |
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