Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites
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* Corresponding author: Ikeoluwapo O Ajayi ikeajayi2003@yahoo.com
Malaria Journal 2008, 7:6 doi:10.1186/1475-2875-7-6
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BioMed Central: 15 citations
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Research
Hailemariam Lemma, Curt Löfgren, Miguel San Sebastian Malaria Journal 2011, 10:349 (5 December 2011) An interesting study of how artemether-lumefantrine is used in practice in Ethiopia. It highlights that adherence to treatment is a major concern, something that may not be fully appreciated by all practitioners.
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Methodology
Insaf F Khalil, Michael Alifrangis, Camilla Recke, Lotte C Hoegberg, Anita Ronn, Ib C Bygbjerg, Claus Koch Malaria Journal 2011, 10:249 (24 August 2011) Development of an ELISA test which can be used for quality screening of CQ in pharmaceutical formulations and for drug monitoring in situations where CQ remains an effective therapeutic agent.
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Research
Patricia Akweongo, Peter Agyei-Baffour, Morankar Sudhakar, Bertha N Simwaka, Amadou T Konaté, Philip B Adongo, Edmund NL Browne, Ayalew Tegegn, Doreen Ali, Abdoulaye Traoré, Mary Amuyunzu-Nyamongo, Franco Pagnoni, Guy Barnish Malaria Journal 2011, 10:240 (16 August 2011) The concept of community case management of malaria in an urban environment was positive, and caregivers were generally satisfied with the services. Quality of services delivered were similar to those seen in rural CCMm settings. Urban CCMm is feasible, but it struggles against other sources of established healthcare providers. Innovation is required by everyone to make it viable.
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Research article
Kwaku P Asante, Livesy Abokyi, Charles Zandoh, Ruth Owusu, Elizabeth Awini, Abubakari Sulemana, Seeba Amenga-Etego, Robert Adda, Owusu Boahen, Sylvester Segbaya, Emmanuel Mahama, Constance Bart-Plange, Daniel Chandramohan, Seth Owusu-Agyei BMC Public Health 2010, 10:409 (12 July 2010) |
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Research
Barriers to prompt and effective malaria treatment among the poorest population in Kenya Jane Chuma, Vincent Okungu, Catherine Molyneux Malaria Journal 2010, 9:144 (27 May 2010) Evidence suggests that the poorest populations benefit less from malaria control interventions, and are less likely to seek prompt and effective treatment.
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Research
Lucy A Smith, Caroline Jones, Rose O Adjei, Gifty D Antwi, Nana A Afrah, Brian Greenwood, Daniel Chandramohan, Harry Tagbor, Jayne Webster Malaria Journal 2010, 9:18 (14 January 2010) Due to very high and increasing resistance of malaria parasites to SP in Africa there is a need for alternative methods to protect pregnant women from the effects of malaria in pregnancy. This study describes pregnant women’s acceptability of such an alternative method based on intermittent RDT screening followed by treatment of those found positive.
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Review
Coartem®: the journey to the clinic Zulfiqarali G Premji Malaria Journal 2009, 8(Suppl 1):S3 (12 October 2009) |
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Research
Elizeus Rutebemberwa, Xavier Nsabagasani, George Pariyo, Goran Tomson, Stefan Peterson, Karin Kallander Malaria Journal 2009, 8:131 (12 June 2009) A qualitative study from a Ugandan district exploring caretaker’s perceptions and practices towards the management of febrile illness in the community
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Research
Jean Ndiaye, Milijaona Randrianarivelojosia, Issaka Sagara, Philippe Brasseur, Ibrahima Ndiaye, Babacar Faye, Laurence Randrianasolo, Arsène Ratsimbasoa, Doris Forlemu, Vicky Moor, Aminata Traore, Yahia Dicko, Niawanlou Dara, Valérie Lameyre, Mouctar Diallo, Abdoulaye Djimde, Albert Same-Ekobo, Oumar Gaye Malaria Journal 2009, 8:125 (8 June 2009) A carefully-conducted clinical trial presenting a three-armed randomized, non-inferiority, multicentre study of a fixed-dose artesunate-amodiaquine combination either administered once or twice daily compared with standard artemether-lumefantrine treatment during a follow-up duration of 28 days with PCR-corrected cure rates.
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Research
Elizeus Rutebemberwa, George Pariyo, Stefan Peterson, Goran Tomson, Karin Kallander Malaria Journal 2009, 8:45 (14 March 2009) This paper deals with a very relevant topic: how to improve access to health care. The authors provide a good insight for reasons why caretakers may still prefer to take their children to the private sector despite having to pay a fee as oppose to the Governmental hospitals.
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Review
Deployment of ACT antimalarials for treatment of malaria: challenges and opportunities Christopher JM Whitty, Clare Chandler, Evelyn Ansah, Toby Leslie, Sarah G Staedke Malaria Journal 2008, 7(Suppl 1):S7 (11 December 2008) |
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Research article
Helena Hildenwall, Göran Tomson, Judith Kaija, George Pariyo, Stefan Peterson BMC International Health and Human Rights 2008, 8:12 (2 December 2008) Reducing mortality in children suffering from acute febrile illnesses in rural communities in the developing world requires improved training for both caretakers and health professionals together with better resourced primary health care centers.
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Research
Alfred B Tiono, Youssouf Kaboré, Abdoulaye Traoré, Nathalie Convelbo, Franco Pagnoni, Sodiomon B Sirima Malaria Journal 2008, 7:201 (3 October 2008) The study shows that improved delivery of antimalarial treatment at the community level may also decrease the burden on the formal health care system, which is often understaffed and overworked.
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Research
Ikeoluwapo O Ajayi, Edmund N Browne, Fred Bateganya, Denis Yar, Christian Happi, Catherine O Falade, Grace O Gbotosho, Bidemi Yusuf, Samuel Boateng, Kefas Mugittu, Simon Cousens, Miriam Nanyunja, Franco Pagnoni Malaria Journal 2008, 7:190 (27 September 2008) A timely report on an ambitious investigation of parasitological cure rates resulting from use of ACTs within the context of HMM in three African countries. This study helps filling the gaps in evidence needed to guide effective implementation of HMM programmes
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Research
Amy C Sievers, Jenifer Lewey, Placide Musafiri, Molly F Franke, Blaise J Bucyibaruta, Sara N Stulac, Michael L Rich, Corine Karema, Johanna P Daily Malaria Journal 2008, 7:167 (27 August 2008) A paper presenting interesting data on the effectiveness evaluation of the wide-scale implementation of ITNs and community-based malaria treatment.
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